Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280491577> ?p ?o ?g. }
- W4280491577 endingPage "715" @default.
- W4280491577 startingPage "715" @default.
- W4280491577 abstract "As bulk chemicals, diols have wide applications in many fields, such as clothing, biofuels, food, surfactant and cosmetics. The traditional chemical synthesis of diols consumes numerous non-renewable energy resources and leads to environmental pollution. Green biosynthesis has emerged as an alternative method to produce diols. Escherichia coli as an ideal microbial factory has been engineered to biosynthesize diols from carbon sources. Here, we comprehensively summarized the biosynthetic pathways of diols from renewable biomass in E. coli and discussed the metabolic-engineering strategies that could enhance the production of diols, including the optimization of biosynthetic pathways, improvement of cofactor supplementation, and reprogramming of the metabolic network. We then investigated the dynamic regulation by multiple control modules to balance the growth and production, so as to direct carbon sources for diol production. Finally, we proposed the challenges in the diol-biosynthesis process and suggested some potential methods to improve the diol-producing ability of the host." @default.
- W4280491577 created "2022-05-22" @default.
- W4280491577 creator A5015933906 @default.
- W4280491577 creator A5024956998 @default.
- W4280491577 creator A5032619855 @default.
- W4280491577 creator A5072246677 @default.
- W4280491577 creator A5081848302 @default.
- W4280491577 date "2022-05-18" @default.
- W4280491577 modified "2023-10-01" @default.
- W4280491577 title "Metabolic Engineering and Regulation of Diol Biosynthesis from Renewable Biomass in Escherichia coli" @default.
- W4280491577 cites W1517043483 @default.
- W4280491577 cites W1904781305 @default.
- W4280491577 cites W1940390557 @default.
- W4280491577 cites W1963779083 @default.
- W4280491577 cites W1967084994 @default.
- W4280491577 cites W1969337918 @default.
- W4280491577 cites W1975471254 @default.
- W4280491577 cites W1976609472 @default.
- W4280491577 cites W1979482176 @default.
- W4280491577 cites W1985859680 @default.
- W4280491577 cites W1990812533 @default.
- W4280491577 cites W1992618877 @default.
- W4280491577 cites W2009570624 @default.
- W4280491577 cites W2010402977 @default.
- W4280491577 cites W2011694692 @default.
- W4280491577 cites W2027780118 @default.
- W4280491577 cites W2036877803 @default.
- W4280491577 cites W2040819411 @default.
- W4280491577 cites W2072862994 @default.
- W4280491577 cites W2075751235 @default.
- W4280491577 cites W2081799587 @default.
- W4280491577 cites W2085328978 @default.
- W4280491577 cites W2087940274 @default.
- W4280491577 cites W2094807715 @default.
- W4280491577 cites W2095574303 @default.
- W4280491577 cites W2099586831 @default.
- W4280491577 cites W2115833799 @default.
- W4280491577 cites W2132931524 @default.
- W4280491577 cites W2140878537 @default.
- W4280491577 cites W2148238625 @default.
- W4280491577 cites W2152572010 @default.
- W4280491577 cites W2152970441 @default.
- W4280491577 cites W2153668144 @default.
- W4280491577 cites W2160076612 @default.
- W4280491577 cites W2161486045 @default.
- W4280491577 cites W2161782059 @default.
- W4280491577 cites W2165612309 @default.
- W4280491577 cites W2170311423 @default.
- W4280491577 cites W2196670136 @default.
- W4280491577 cites W2212575086 @default.
- W4280491577 cites W2214411608 @default.
- W4280491577 cites W2228099278 @default.
- W4280491577 cites W2254993872 @default.
- W4280491577 cites W2257973474 @default.
- W4280491577 cites W2263951705 @default.
- W4280491577 cites W2291326678 @default.
- W4280491577 cites W2314052350 @default.
- W4280491577 cites W2319211710 @default.
- W4280491577 cites W2333332623 @default.
- W4280491577 cites W2344431831 @default.
- W4280491577 cites W2547212295 @default.
- W4280491577 cites W2588978634 @default.
- W4280491577 cites W2614803065 @default.
- W4280491577 cites W2618525505 @default.
- W4280491577 cites W265103218 @default.
- W4280491577 cites W2750827051 @default.
- W4280491577 cites W2765127462 @default.
- W4280491577 cites W2786189709 @default.
- W4280491577 cites W2790192196 @default.
- W4280491577 cites W2795654653 @default.
- W4280491577 cites W2799446833 @default.
- W4280491577 cites W2806493503 @default.
- W4280491577 cites W2808945488 @default.
- W4280491577 cites W2883863908 @default.
- W4280491577 cites W2889233581 @default.
- W4280491577 cites W2900330809 @default.
- W4280491577 cites W2903185930 @default.
- W4280491577 cites W2912036672 @default.
- W4280491577 cites W2913683772 @default.
- W4280491577 cites W2968439292 @default.
- W4280491577 cites W2976976639 @default.
- W4280491577 cites W3006061824 @default.
- W4280491577 cites W3011438738 @default.
- W4280491577 cites W3015486656 @default.
- W4280491577 cites W3027058118 @default.
- W4280491577 cites W3045553628 @default.
- W4280491577 cites W3083242595 @default.
- W4280491577 cites W3084782289 @default.
- W4280491577 cites W3089916935 @default.
- W4280491577 cites W3091986997 @default.
- W4280491577 cites W3097223481 @default.
- W4280491577 cites W3123639106 @default.
- W4280491577 cites W3125306687 @default.
- W4280491577 cites W3129270947 @default.
- W4280491577 cites W3134483012 @default.
- W4280491577 cites W3136410702 @default.
- W4280491577 cites W3139020078 @default.
- W4280491577 cites W3169536917 @default.