Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280491809> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4280491809 endingPage "1269" @default.
- W4280491809 startingPage "1262" @default.
- W4280491809 abstract "Acne vulgaris (AV) is an inflammatory skin disease of the pilosebaceous unit. S100A8 and S100A9 (the light subunits of calprotectin) gene polymorphisms have been known to be associated with inflammatory disorder. Until now, no study investigated calprotectin gene polymorphism in acne patients.This study was designed to investigate calprotectin serum levels and gene polymorphism (rs3806232) in acne vulgaris patients and to correlate them with different clinical aspects of them.This case-control study included 50 patients having variable degrees of acne vulgaris (AV) severity, in addition to a control group of 26 age- and gender-matched seemingly healthy volunteers.Acne vulgaris patients had considerably greater (P < 0.001) mean serum calprotectin levels than the control group (3.86 ± 2.58 pg/ml vs. 0.29 ± 0.14). AA genotype of calprotectin S100 A8 (rs3806232) was significantly predominant over AG or GG genotypes in patients compared to the controls, and the A allele was significantly (P < 0.001) predominant in patients (80%), while A and G alleles were equally distributed in controls; also, there was a significantly higher serum calprotectin level in calprotectin AA genotype than in AG or GG (P < 0.001) in acne vulgaris patients.The serum levels of calprotectin were considerably greater in AV patients than in controls. AA genotype and A allele of the S100 A8 gene were significantly higher in patients, which was associated with significantly higher calprotectin serum levels. Thus, calprotectin, both gene and serum level, might participate in disease pathogenesis, which needs further studies." @default.
- W4280491809 created "2022-05-22" @default.
- W4280491809 creator A5011686508 @default.
- W4280491809 creator A5022934495 @default.
- W4280491809 creator A5052828551 @default.
- W4280491809 creator A5071478014 @default.
- W4280491809 date "2022-05-17" @default.
- W4280491809 modified "2023-10-02" @default.
- W4280491809 title "Study of calprotectin gene polymorphism and serum level in acne vulgaris patients" @default.
- W4280491809 cites W151656921 @default.
- W4280491809 cites W1751974138 @default.
- W4280491809 cites W1924525065 @default.
- W4280491809 cites W1950981769 @default.
- W4280491809 cites W1971883262 @default.
- W4280491809 cites W2062152303 @default.
- W4280491809 cites W2074489676 @default.
- W4280491809 cites W2099998572 @default.
- W4280491809 cites W2112590416 @default.
- W4280491809 cites W2582724478 @default.
- W4280491809 cites W2586603260 @default.
- W4280491809 cites W2888686197 @default.
- W4280491809 cites W2927407089 @default.
- W4280491809 cites W3038067995 @default.
- W4280491809 cites W3187057677 @default.
- W4280491809 doi "https://doi.org/10.1111/ijd.16268" @default.
- W4280491809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35579306" @default.
- W4280491809 hasPublicationYear "2022" @default.
- W4280491809 type Work @default.
- W4280491809 citedByCount "1" @default.
- W4280491809 countsByYear W42804918092023 @default.
- W4280491809 crossrefType "journal-article" @default.
- W4280491809 hasAuthorship W4280491809A5011686508 @default.
- W4280491809 hasAuthorship W4280491809A5022934495 @default.
- W4280491809 hasAuthorship W4280491809A5052828551 @default.
- W4280491809 hasAuthorship W4280491809A5071478014 @default.
- W4280491809 hasConcept C104317684 @default.
- W4280491809 hasConcept C126322002 @default.
- W4280491809 hasConcept C135763542 @default.
- W4280491809 hasConcept C149737253 @default.
- W4280491809 hasConcept C16005928 @default.
- W4280491809 hasConcept C180754005 @default.
- W4280491809 hasConcept C203014093 @default.
- W4280491809 hasConcept C2776307749 @default.
- W4280491809 hasConcept C2776914184 @default.
- W4280491809 hasConcept C2777673923 @default.
- W4280491809 hasConcept C2778260677 @default.
- W4280491809 hasConcept C2778292693 @default.
- W4280491809 hasConcept C2778557267 @default.
- W4280491809 hasConcept C2779134260 @default.
- W4280491809 hasConcept C2780942790 @default.
- W4280491809 hasConcept C37463918 @default.
- W4280491809 hasConcept C54355233 @default.
- W4280491809 hasConcept C71924100 @default.
- W4280491809 hasConcept C76252995 @default.
- W4280491809 hasConcept C86803240 @default.
- W4280491809 hasConcept C90924648 @default.
- W4280491809 hasConceptScore W4280491809C104317684 @default.
- W4280491809 hasConceptScore W4280491809C126322002 @default.
- W4280491809 hasConceptScore W4280491809C135763542 @default.
- W4280491809 hasConceptScore W4280491809C149737253 @default.
- W4280491809 hasConceptScore W4280491809C16005928 @default.
- W4280491809 hasConceptScore W4280491809C180754005 @default.
- W4280491809 hasConceptScore W4280491809C203014093 @default.
- W4280491809 hasConceptScore W4280491809C2776307749 @default.
- W4280491809 hasConceptScore W4280491809C2776914184 @default.
- W4280491809 hasConceptScore W4280491809C2777673923 @default.
- W4280491809 hasConceptScore W4280491809C2778260677 @default.
- W4280491809 hasConceptScore W4280491809C2778292693 @default.
- W4280491809 hasConceptScore W4280491809C2778557267 @default.
- W4280491809 hasConceptScore W4280491809C2779134260 @default.
- W4280491809 hasConceptScore W4280491809C2780942790 @default.
- W4280491809 hasConceptScore W4280491809C37463918 @default.
- W4280491809 hasConceptScore W4280491809C54355233 @default.
- W4280491809 hasConceptScore W4280491809C71924100 @default.
- W4280491809 hasConceptScore W4280491809C76252995 @default.
- W4280491809 hasConceptScore W4280491809C86803240 @default.
- W4280491809 hasConceptScore W4280491809C90924648 @default.
- W4280491809 hasIssue "10" @default.
- W4280491809 hasLocation W42804918091 @default.
- W4280491809 hasLocation W42804918092 @default.
- W4280491809 hasOpenAccess W4280491809 @default.
- W4280491809 hasPrimaryLocation W42804918091 @default.
- W4280491809 hasRelatedWork W1975509404 @default.
- W4280491809 hasRelatedWork W1993917509 @default.
- W4280491809 hasRelatedWork W2020364677 @default.
- W4280491809 hasRelatedWork W2183846840 @default.
- W4280491809 hasRelatedWork W2357736479 @default.
- W4280491809 hasRelatedWork W2362188934 @default.
- W4280491809 hasRelatedWork W2378768101 @default.
- W4280491809 hasRelatedWork W2386446805 @default.
- W4280491809 hasRelatedWork W2394303093 @default.
- W4280491809 hasRelatedWork W2957163721 @default.
- W4280491809 hasVolume "61" @default.
- W4280491809 isParatext "false" @default.
- W4280491809 isRetracted "false" @default.
- W4280491809 workType "article" @default.