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- W4280492338 abstract "• Paraneoplastic myelopathy (PM) only accounts for 6.5% of the total PNS, most commonly caused by lung and breast carcinoma, while thyroid carcinoma is an extremely rare cause. • Here we report a case of isolated myelopathy caused by papillary thyroid carcinoma. • The patient's symptoms alleviated obviously one month after right thyroid lobe and lymph node excision only with mild gait disturbance left, he fully recovered at follow-up one year after surgery. • Clinicians must be alert to the possibility of PM for the insidious onset of the rare isolated myelopathy followed by thyroid carcinoma. • It should be combined with other related auxiliary examinations to make up for the false negative rate of paraneoplastic autoantibodies in order to treat malignant tumors in a timely and effective manner. A young Chinese male suffered from progressive gait disturbance and ataxia for five years. Symmetric longitudinally extensive hyperintensity on T2WI involving C5-T7 segments was found by Spinal MRI. Thyroid ultrasound indicated that he had multiple parenchymal nodules in the right lobe with calcification in the larger ones (TI-RADS: 4b). The puncture of the right thyroid lobe indicated classic papillary carcinoma with capsule invasion and vascular lymph node infiltration. His symptoms alleviated obviously one month after right thyroid lobe and lymph node excision only with mild gait disturbance left. The patient fully recovered at follow-up one year after surgery." @default.
- W4280492338 created "2022-05-22" @default.
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- W4280492338 date "2022-09-01" @default.
- W4280492338 modified "2023-09-26" @default.
- W4280492338 title "A patient of isolated myelopathy secondary to papillary thyroid carcinoma with excellent response to surgical resection" @default.
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- W4280492338 doi "https://doi.org/10.1016/j.inat.2022.101586" @default.
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