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• W4280492570 abstract "Sensory systems need to process signals in a highly dynamic way to efficiently respond to variations in the animal’s environment. For instance, several studies showed that the visual system is subject to neuroplasticity since the neurons’ firing changes according to stimulus properties. This dynamic information processing might be supported by a network reorganization. Since antidepressants influence neurotransmission, they can be used to explore synaptic plasticity sustaining cortical map reorganization. To this goal, we investigated in the primary visual cortex (V1 of mouse and cat), the impact of ketamine on neuroplasticity through changes in neuronal orientation selectivity and the functional connectivity between V1 cells, using cross correlation analyses. We found that ketamine affects cortical orientation selectivity and alters the functional connectivity within an assembly. These data clearly highlight the role of the antidepressant drugs in inducing or modeling short-term plasticity in V1 which suggests that cortical processing is optimized and adapted to the properties of the stimulus." @default.
• W4280492570 created "2022-05-22" @default.
• W4280492570 creator A5005403665 @default.
• W4280492570 creator A5020437674 @default.
• W4280492570 creator A5022413086 @default.
• W4280492570 date "2022-09-14" @default.
• W4280492570 modified "2023-10-01" @default.
• W4280492570 title "Cortical Plasticity under Ketamine: From Synapse to Map" @default.
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