Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280493362> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4280493362 endingPage "020" @default.
- W4280493362 startingPage "006" @default.
- W4280493362 abstract "Crohn's disease is a chronic syndrome of the gastrointestinal tract that produces idiopathic inflammation. Approximately half of the patients develop abscesses and/or fistulas throughout their history that are located, mainly, in the perianal region. Current treatments are based on individualized plans that generally use combined pharmacology for symptomatic relief based on glucocorticoids, immunosuppressants or immunomodulators, antibiotics, anti-inflammatories, probiotics, and antibodies, or surgical therapies such as intestinal resections or ostomizations (colostomy and ileostomy) that tend to cause notable side effects in a considerable percentage of patients and a significant decrease in their quality of life. Perianal fistulas consist of abnormal tracts, inflammatory tunnels, or chronic tracts of granular tissue that connect two surfaces lined with epithelium, have an external hole in the skin that borders the anus, and an internal hole located inside it around the anal canal, rectus and sphincters. Treatment is a complex process that requires a multidisciplinary approach and the combination of several treatments. In the short term, the goal is to drain abscesses, reduce inflammatory and infectious processes, guard the fistulous tract with seton or lax lines, facilitate patency, and hinder new formations. In the long term, a total cure and the avoidance of complications that require surgery or the creation of intestinal stomas are pursued. For this reason, new effective remedies with fewer adverse effects continue to be investigated, one of the most promising being the use of mesenchymal stem cells for the regeneration and cure of perianal fistulas and the remission of symptoms. The present bibliographic review delves into this new therapy and analyzes the current state of the situation regarding its efficacy and safety." @default.
- W4280493362 created "2022-05-22" @default.
- W4280493362 creator A5008979789 @default.
- W4280493362 creator A5029758699 @default.
- W4280493362 creator A5040985383 @default.
- W4280493362 creator A5043905538 @default.
- W4280493362 creator A5069352291 @default.
- W4280493362 date "2022-05-04" @default.
- W4280493362 modified "2023-10-14" @default.
- W4280493362 title "Treatment of perianal fistulae in crohn's disease with mesenchymal stem cells" @default.
- W4280493362 cites W1852715977 @default.
- W4280493362 cites W2508710172 @default.
- W4280493362 cites W2602119493 @default.
- W4280493362 cites W2746710261 @default.
- W4280493362 cites W2749814893 @default.
- W4280493362 cites W2751308524 @default.
- W4280493362 cites W2771835295 @default.
- W4280493362 cites W2779701523 @default.
- W4280493362 cites W2780607073 @default.
- W4280493362 cites W2790210118 @default.
- W4280493362 cites W2805320230 @default.
- W4280493362 cites W2908724033 @default.
- W4280493362 cites W2912374965 @default.
- W4280493362 cites W2915776629 @default.
- W4280493362 cites W2925850961 @default.
- W4280493362 cites W2940880454 @default.
- W4280493362 cites W2943025875 @default.
- W4280493362 cites W2943914150 @default.
- W4280493362 cites W2951537203 @default.
- W4280493362 cites W2953590424 @default.
- W4280493362 cites W2963679336 @default.
- W4280493362 cites W2966904752 @default.
- W4280493362 cites W3003053688 @default.
- W4280493362 cites W3023626526 @default.
- W4280493362 cites W3038519325 @default.
- W4280493362 cites W3094857686 @default.
- W4280493362 cites W3120301604 @default.
- W4280493362 cites W3138150943 @default.
- W4280493362 doi "https://doi.org/10.29328/journal.acgh.1001033" @default.
- W4280493362 hasPublicationYear "2022" @default.
- W4280493362 type Work @default.
- W4280493362 citedByCount "0" @default.
- W4280493362 crossrefType "journal-article" @default.
- W4280493362 hasAuthorship W4280493362A5008979789 @default.
- W4280493362 hasAuthorship W4280493362A5029758699 @default.
- W4280493362 hasAuthorship W4280493362A5040985383 @default.
- W4280493362 hasAuthorship W4280493362A5043905538 @default.
- W4280493362 hasAuthorship W4280493362A5069352291 @default.
- W4280493362 hasBestOaLocation W42804933621 @default.
- W4280493362 hasConcept C126322002 @default.
- W4280493362 hasConcept C141071460 @default.
- W4280493362 hasConcept C142724271 @default.
- W4280493362 hasConcept C16005928 @default.
- W4280493362 hasConcept C197934379 @default.
- W4280493362 hasConcept C198826908 @default.
- W4280493362 hasConcept C2778766689 @default.
- W4280493362 hasConcept C2779134260 @default.
- W4280493362 hasConcept C2779280984 @default.
- W4280493362 hasConcept C2779973185 @default.
- W4280493362 hasConcept C71924100 @default.
- W4280493362 hasConceptScore W4280493362C126322002 @default.
- W4280493362 hasConceptScore W4280493362C141071460 @default.
- W4280493362 hasConceptScore W4280493362C142724271 @default.
- W4280493362 hasConceptScore W4280493362C16005928 @default.
- W4280493362 hasConceptScore W4280493362C197934379 @default.
- W4280493362 hasConceptScore W4280493362C198826908 @default.
- W4280493362 hasConceptScore W4280493362C2778766689 @default.
- W4280493362 hasConceptScore W4280493362C2779134260 @default.
- W4280493362 hasConceptScore W4280493362C2779280984 @default.
- W4280493362 hasConceptScore W4280493362C2779973185 @default.
- W4280493362 hasConceptScore W4280493362C71924100 @default.
- W4280493362 hasIssue "1" @default.
- W4280493362 hasLocation W42804933621 @default.
- W4280493362 hasOpenAccess W4280493362 @default.
- W4280493362 hasPrimaryLocation W42804933621 @default.
- W4280493362 hasRelatedWork W1164793 @default.
- W4280493362 hasRelatedWork W1320415 @default.
- W4280493362 hasRelatedWork W13579090 @default.
- W4280493362 hasRelatedWork W1618377 @default.
- W4280493362 hasRelatedWork W16629 @default.
- W4280493362 hasRelatedWork W1720004 @default.
- W4280493362 hasRelatedWork W3330043 @default.
- W4280493362 hasRelatedWork W4811995 @default.
- W4280493362 hasRelatedWork W4818676 @default.
- W4280493362 hasRelatedWork W975629 @default.
- W4280493362 hasVolume "6" @default.
- W4280493362 isParatext "false" @default.
- W4280493362 isRetracted "false" @default.
- W4280493362 workType "article" @default.