Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280493733> ?p ?o ?g. }
- W4280493733 abstract "Abstract Osteoarthritis (OA) is one of the most common musculoskeletal degenerative diseases and contributes to heavy socioeconomic burden. Current pharmacological and conventional non-pharmacological therapies aim at relieving the symptoms like pain and disability rather than modifying the underlying disease. Surgical treatment and ultimately joint replacement arthroplasty are indicated in advanced stages of OA. Since the underlying mechanisms of OA onset and progression have not been fully elucidated yet, the development of novel therapeutics to prevent, halt, or reverse the disease is laborious. Recently, small molecules of herbal origin have been reported to show potent anti-inflammatory, anti-catabolic, and anabolic effects, implying their potential for treatment of OA. Herein, the molecular mechanisms of these small molecules, their effect on physiological or pathological signaling pathways, the advancement of the extraction methods, and their potential clinical translation based on in vitro and in vivo evidence are comprehensively reviewed." @default.
- W4280493733 created "2022-05-22" @default.
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- W4280493733 creator A5075240056 @default.
- W4280493733 date "2022-05-11" @default.
- W4280493733 modified "2023-10-05" @default.
- W4280493733 title "Small molecules of herbal origin for osteoarthritis treatment: in vitro and in vivo evidence" @default.
- W4280493733 cites W1779082924 @default.
- W4280493733 cites W1830008011 @default.
- W4280493733 cites W1969098410 @default.
- W4280493733 cites W1974328595 @default.
- W4280493733 cites W1975695280 @default.
- W4280493733 cites W1976382352 @default.
- W4280493733 cites W1977091634 @default.
- W4280493733 cites W1998305047 @default.
- W4280493733 cites W1999963870 @default.
- W4280493733 cites W2001932041 @default.
- W4280493733 cites W2002165245 @default.
- W4280493733 cites W2014140858 @default.
- W4280493733 cites W2014311475 @default.
- W4280493733 cites W2016158020 @default.
- W4280493733 cites W2017869529 @default.
- W4280493733 cites W2021917597 @default.
- W4280493733 cites W2029361033 @default.
- W4280493733 cites W2031565825 @default.
- W4280493733 cites W2036491373 @default.
- W4280493733 cites W2036752543 @default.
- W4280493733 cites W2037258027 @default.
- W4280493733 cites W2042845877 @default.
- W4280493733 cites W2042913647 @default.
- W4280493733 cites W2043125425 @default.
- W4280493733 cites W2052232504 @default.
- W4280493733 cites W2061410906 @default.
- W4280493733 cites W2086847144 @default.
- W4280493733 cites W2086916208 @default.
- W4280493733 cites W2094725156 @default.
- W4280493733 cites W2095835247 @default.
- W4280493733 cites W2098082628 @default.
- W4280493733 cites W2103495251 @default.
- W4280493733 cites W2105565758 @default.
- W4280493733 cites W2105907195 @default.
- W4280493733 cites W2106291803 @default.
- W4280493733 cites W2106582491 @default.
- W4280493733 cites W2107660351 @default.
- W4280493733 cites W2108308287 @default.
- W4280493733 cites W2108344016 @default.
- W4280493733 cites W2109118586 @default.
- W4280493733 cites W2114795867 @default.
- W4280493733 cites W2117327528 @default.
- W4280493733 cites W2122044177 @default.
- W4280493733 cites W2132612143 @default.
- W4280493733 cites W2133915381 @default.
- W4280493733 cites W2134705682 @default.
- W4280493733 cites W2135122709 @default.
- W4280493733 cites W2137203336 @default.
- W4280493733 cites W2137854259 @default.
- W4280493733 cites W2140513563 @default.
- W4280493733 cites W2147148117 @default.
- W4280493733 cites W2147921405 @default.
- W4280493733 cites W2151620005 @default.
- W4280493733 cites W2161736885 @default.
- W4280493733 cites W2164403708 @default.
- W4280493733 cites W2166846320 @default.
- W4280493733 cites W2191037725 @default.
- W4280493733 cites W2212499052 @default.
- W4280493733 cites W2274971583 @default.
- W4280493733 cites W2286663861 @default.
- W4280493733 cites W2404598608 @default.
- W4280493733 cites W2406503880 @default.
- W4280493733 cites W2414302576 @default.
- W4280493733 cites W2473668993 @default.
- W4280493733 cites W2507683743 @default.
- W4280493733 cites W2512095388 @default.
- W4280493733 cites W2518546450 @default.
- W4280493733 cites W2521335702 @default.
- W4280493733 cites W2546218191 @default.
- W4280493733 cites W2584503597 @default.
- W4280493733 cites W2587859089 @default.
- W4280493733 cites W2589583989 @default.
- W4280493733 cites W2593978377 @default.
- W4280493733 cites W2600568230 @default.
- W4280493733 cites W2668593039 @default.
- W4280493733 cites W2732010539 @default.
- W4280493733 cites W2734661554 @default.
- W4280493733 cites W2735527928 @default.
- W4280493733 cites W2737711400 @default.
- W4280493733 cites W2744732753 @default.
- W4280493733 cites W2750655256 @default.
- W4280493733 cites W2751884637 @default.
- W4280493733 cites W2762632609 @default.
- W4280493733 cites W2771382973 @default.