Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280494704> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4280494704 abstract "This article revisits the hypothesis, proposed in 2002, that the successful development of oocytes and preimplantation mammalian embryos is associated with a metabolism which is quiet rather than active, within limits which had yet to be defined. A distinction was drawn between Functional Quietness, Loss of quietness in response to stress and Inter-individual differences in embryo metabolism and here we document applications of the hypothesis to other areas of reproductive biology. In order to encompass the requirement for limits and replace the simple distinction between quiet and active, evidence is presented which led to a re-working of the hypothesis by proposing the existence of an optimal range of metabolic activity, termed a Goldilocks zone, within which oocytes and embryos with maximum developmental potential will be located. General and specific mechanisms which may underlie the Goldilocks phenomenon are proposed and the added value that may be derived by expressing data on individual embryos as distributions rather than mean values is emphasised especially in the context of the response of early embryos to stress and to the concept of the Developmental Origins of Health and Disease. The article concludes with a cautionary note that being quietly efficient may not always ensure optimal embryo survival." @default.
- W4280494704 created "2022-05-22" @default.
- W4280494704 creator A5003101926 @default.
- W4280494704 creator A5040923705 @default.
- W4280494704 creator A5057703824 @default.
- W4280494704 date "2022-05-11" @default.
- W4280494704 modified "2023-10-06" @default.
- W4280494704 title "The Quiet Embryo Hypothesis: 20 years on" @default.
- W4280494704 cites W1969640830 @default.
- W4280494704 cites W1982788342 @default.
- W4280494704 cites W1988759347 @default.
- W4280494704 cites W2011359538 @default.
- W4280494704 cites W2014468242 @default.
- W4280494704 cites W2024815822 @default.
- W4280494704 cites W2031202642 @default.
- W4280494704 cites W2035010201 @default.
- W4280494704 cites W2040232631 @default.
- W4280494704 cites W2050545911 @default.
- W4280494704 cites W2065346340 @default.
- W4280494704 cites W2069548177 @default.
- W4280494704 cites W2074682657 @default.
- W4280494704 cites W2098610574 @default.
- W4280494704 cites W2104856513 @default.
- W4280494704 cites W2108531322 @default.
- W4280494704 cites W2111075937 @default.
- W4280494704 cites W2115523693 @default.
- W4280494704 cites W2116306018 @default.
- W4280494704 cites W2116574982 @default.
- W4280494704 cites W2117371378 @default.
- W4280494704 cites W2123704932 @default.
- W4280494704 cites W2130852301 @default.
- W4280494704 cites W2138560227 @default.
- W4280494704 cites W2143881564 @default.
- W4280494704 cites W2148734614 @default.
- W4280494704 cites W2150825979 @default.
- W4280494704 cites W2159467731 @default.
- W4280494704 cites W2160819114 @default.
- W4280494704 cites W2164030497 @default.
- W4280494704 cites W2493731915 @default.
- W4280494704 cites W2583597065 @default.
- W4280494704 cites W2902740934 @default.
- W4280494704 cites W2989746383 @default.
- W4280494704 cites W3081466492 @default.
- W4280494704 cites W590240299 @default.
- W4280494704 doi "https://doi.org/10.3389/fphys.2022.899485" @default.
- W4280494704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35634152" @default.
- W4280494704 hasPublicationYear "2022" @default.
- W4280494704 type Work @default.
- W4280494704 citedByCount "9" @default.
- W4280494704 countsByYear W42804947042022 @default.
- W4280494704 countsByYear W42804947042023 @default.
- W4280494704 crossrefType "journal-article" @default.
- W4280494704 hasAuthorship W4280494704A5003101926 @default.
- W4280494704 hasAuthorship W4280494704A5040923705 @default.
- W4280494704 hasAuthorship W4280494704A5057703824 @default.
- W4280494704 hasBestOaLocation W42804947041 @default.
- W4280494704 hasConcept C121332964 @default.
- W4280494704 hasConcept C151730666 @default.
- W4280494704 hasConcept C177321328 @default.
- W4280494704 hasConcept C196843134 @default.
- W4280494704 hasConcept C2777185736 @default.
- W4280494704 hasConcept C2779343474 @default.
- W4280494704 hasConcept C54355233 @default.
- W4280494704 hasConcept C62520636 @default.
- W4280494704 hasConcept C78458016 @default.
- W4280494704 hasConcept C86803240 @default.
- W4280494704 hasConcept C87355193 @default.
- W4280494704 hasConceptScore W4280494704C121332964 @default.
- W4280494704 hasConceptScore W4280494704C151730666 @default.
- W4280494704 hasConceptScore W4280494704C177321328 @default.
- W4280494704 hasConceptScore W4280494704C196843134 @default.
- W4280494704 hasConceptScore W4280494704C2777185736 @default.
- W4280494704 hasConceptScore W4280494704C2779343474 @default.
- W4280494704 hasConceptScore W4280494704C54355233 @default.
- W4280494704 hasConceptScore W4280494704C62520636 @default.
- W4280494704 hasConceptScore W4280494704C78458016 @default.
- W4280494704 hasConceptScore W4280494704C86803240 @default.
- W4280494704 hasConceptScore W4280494704C87355193 @default.
- W4280494704 hasLocation W42804947041 @default.
- W4280494704 hasLocation W42804947042 @default.
- W4280494704 hasLocation W42804947043 @default.
- W4280494704 hasOpenAccess W4280494704 @default.
- W4280494704 hasPrimaryLocation W42804947041 @default.
- W4280494704 hasRelatedWork W2071213291 @default.
- W4280494704 hasRelatedWork W2075370846 @default.
- W4280494704 hasRelatedWork W2140941076 @default.
- W4280494704 hasRelatedWork W2464035138 @default.
- W4280494704 hasRelatedWork W3092476706 @default.
- W4280494704 hasRelatedWork W3172994143 @default.
- W4280494704 hasRelatedWork W4247168545 @default.
- W4280494704 hasRelatedWork W4256501598 @default.
- W4280494704 hasRelatedWork W4291139288 @default.
- W4280494704 hasRelatedWork W851382200 @default.
- W4280494704 hasVolume "13" @default.
- W4280494704 isParatext "false" @default.
- W4280494704 isRetracted "false" @default.
- W4280494704 workType "article" @default.