Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280496506> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4280496506 abstract "Abstract Suppressing actions is essential for flexible behavior. Multiple neural circuits involved in behavioral inhibition converge upon a key basal ganglia output nucleus, the substantia nigra pars reticulata (SNr). To examine how changes in basal ganglia output contribute to self-restraint, we recorded SNr neurons during a proactive behavioral inhibition task. Rats responded to Go! cues with rapid leftward or rightward movements, but also prepared to cancel one of these movement directions on trials when a Stop! cue might occur. This action restraint – visible as direction-selective slowing of reaction times – altered both rates and patterns of SNr spiking. Overall firing rate was elevated before the Go! cue, and this effect was driven by a subpopulation of direction-selective SNr neurons. In neural state space, this corresponded to a shift away from the restrained movement. SNr neurons also showed more variable inter-spike-intervals during proactive inhibition. This corresponded to more variable state-space trajectories, which may slow reaction times via reduced preparation to move. These findings open new perspectives on how basal ganglia dynamics contribute to movement preparation and cognitive control." @default.
- W4280496506 created "2022-05-22" @default.
- W4280496506 creator A5050466159 @default.
- W4280496506 creator A5071330461 @default.
- W4280496506 date "2022-04-25" @default.
- W4280496506 modified "2023-09-28" @default.
- W4280496506 title "Altered basal ganglia output during self-restraint" @default.
- W4280496506 cites W1589858513 @default.
- W4280496506 cites W1802152092 @default.
- W4280496506 cites W1882131888 @default.
- W4280496506 cites W1905563481 @default.
- W4280496506 cites W1977279821 @default.
- W4280496506 cites W1995185032 @default.
- W4280496506 cites W2001405298 @default.
- W4280496506 cites W2002783050 @default.
- W4280496506 cites W2008098183 @default.
- W4280496506 cites W2018822471 @default.
- W4280496506 cites W2021656654 @default.
- W4280496506 cites W2028116697 @default.
- W4280496506 cites W2032337192 @default.
- W4280496506 cites W2033513858 @default.
- W4280496506 cites W2040499723 @default.
- W4280496506 cites W2042420303 @default.
- W4280496506 cites W2045839462 @default.
- W4280496506 cites W2047683418 @default.
- W4280496506 cites W2048592764 @default.
- W4280496506 cites W2058551164 @default.
- W4280496506 cites W2059107223 @default.
- W4280496506 cites W2059570857 @default.
- W4280496506 cites W2069166530 @default.
- W4280496506 cites W2073395235 @default.
- W4280496506 cites W2093533434 @default.
- W4280496506 cites W2101464959 @default.
- W4280496506 cites W2105031232 @default.
- W4280496506 cites W2105380935 @default.
- W4280496506 cites W2116257195 @default.
- W4280496506 cites W2127313070 @default.
- W4280496506 cites W2139290928 @default.
- W4280496506 cites W2148002450 @default.
- W4280496506 cites W2151316609 @default.
- W4280496506 cites W2170907775 @default.
- W4280496506 cites W2236405376 @default.
- W4280496506 cites W2256669593 @default.
- W4280496506 cites W2471479325 @default.
- W4280496506 cites W2519792407 @default.
- W4280496506 cites W2580936964 @default.
- W4280496506 cites W2756375591 @default.
- W4280496506 cites W2920749554 @default.
- W4280496506 cites W2998938656 @default.
- W4280496506 cites W3033095862 @default.
- W4280496506 cites W3083432548 @default.
- W4280496506 cites W3132931913 @default.
- W4280496506 cites W3216326524 @default.
- W4280496506 doi "https://doi.org/10.1101/2022.04.23.489276" @default.
- W4280496506 hasPublicationYear "2022" @default.
- W4280496506 type Work @default.
- W4280496506 citedByCount "0" @default.
- W4280496506 crossrefType "posted-content" @default.
- W4280496506 hasAuthorship W4280496506A5050466159 @default.
- W4280496506 hasAuthorship W4280496506A5071330461 @default.
- W4280496506 hasBestOaLocation W42804965061 @default.
- W4280496506 hasConcept C137183658 @default.
- W4280496506 hasConcept C15744967 @default.
- W4280496506 hasConcept C169760540 @default.
- W4280496506 hasConcept C2778187257 @default.
- W4280496506 hasConcept C2780938664 @default.
- W4280496506 hasConcept C513476851 @default.
- W4280496506 hasConcept C529278444 @default.
- W4280496506 hasConceptScore W4280496506C137183658 @default.
- W4280496506 hasConceptScore W4280496506C15744967 @default.
- W4280496506 hasConceptScore W4280496506C169760540 @default.
- W4280496506 hasConceptScore W4280496506C2778187257 @default.
- W4280496506 hasConceptScore W4280496506C2780938664 @default.
- W4280496506 hasConceptScore W4280496506C513476851 @default.
- W4280496506 hasConceptScore W4280496506C529278444 @default.
- W4280496506 hasLocation W42804965061 @default.
- W4280496506 hasLocation W42804965062 @default.
- W4280496506 hasOpenAccess W4280496506 @default.
- W4280496506 hasPrimaryLocation W42804965061 @default.
- W4280496506 hasRelatedWork W173243203 @default.
- W4280496506 hasRelatedWork W1971855637 @default.
- W4280496506 hasRelatedWork W1974778249 @default.
- W4280496506 hasRelatedWork W1979689261 @default.
- W4280496506 hasRelatedWork W2001586906 @default.
- W4280496506 hasRelatedWork W2119475064 @default.
- W4280496506 hasRelatedWork W2585455344 @default.
- W4280496506 hasRelatedWork W2979518698 @default.
- W4280496506 hasRelatedWork W3107889278 @default.
- W4280496506 hasRelatedWork W4312341647 @default.
- W4280496506 isParatext "false" @default.
- W4280496506 isRetracted "false" @default.
- W4280496506 workType "article" @default.