FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280496614> ?p ?o ?g. }

• W4280496614 endingPage "100093" @default.
• W4280496614 startingPage "100093" @default.
• W4280496614 abstract "To evaluate changes in cortical thickness and right posterior insula (r-pIns) gamma-aminobutyric acid (GABA) concentrations in veterans with fibromyalgia treated with auricular percutaneous electric nerve field stimulation (PENFS). This was a randomized, controlled, open label investigation conducted in a government hospital. Twenty-one veterans with fibromyalgia were randomized to receive either standard therapy (ST; i.e., 4 weekly visits with a pain practitioner) or ST with auricular PENFS (ST + PENFS). Neuroimaging data was collected at baseline (i.e. before the first treatment session) and again within 2 weeks post-treatment.​ Clinical pain and physical function were also assessed at these timepoints. Single-voxel magnetic resonance spectroscopy was carried out in r-pIns to assess changes in r-pIns GABA concentrations and high-resolution T1-weighted images were collected to assess changes in regional gray matter volume using cortical thickness. Both the ST + PENFS and ST groups reported a decrease in pain with treatment. Volumetric: Cortical thickness significantly decreased in the left middle posterior cingulate (p = 0.018) and increased in the left cuneus (p = 0.014) following ST + PENFS treatment. These findings were significant following FDR correction for multiple comparisons. ST group right hemisphere insula cortical thickness increased post-treatment and was significantly (p = 0.02) inversely correlated with pain scores. ST + PENFS group right hemisphere posterior dorsal cingulate size significantly (p = 0.044) positively correlated with pain scores. GABA: There were no significant correlations with GABA, though a trend was noted towards increased GABA following treatment in both groups (p = 0.083) using a linear mixed effects model. Results suggest a novel effect of PENFS reflected by differential volumetric changes compared to ST. The changes in GABA that occur in both groups are more likely related to ST. Insular GABA and cortical thickness in key regions of interest may be developed as potential biomarkers for evaluating chronic pain pathology and treatment outcomes." @default.
• W4280496614 created "2022-05-22" @default.
• W4280496614 creator A5005337452 @default.
• W4280496614 creator A5007089860 @default.
• W4280496614 creator A5011260334 @default.
• W4280496614 creator A5026641838 @default.
• W4280496614 creator A5029251642 @default.
• W4280496614 creator A5031538608 @default.
• W4280496614 creator A5034311774 @default.
• W4280496614 creator A5035118592 @default.
• W4280496614 creator A5040714412 @default.
• W4280496614 creator A5057767458 @default.
• W4280496614 creator A5059688748 @default.
• W4280496614 creator A5059772146 @default.
• W4280496614 creator A5081665529 @default.
• W4280496614 date "2022-08-01" @default.
• W4280496614 modified "2023-10-15" @default.
• W4280496614 title "Percutaneous electric nerve field stimulation alters cortical thickness in a pilot study of veterans with fibromyalgia" @default.
• W4280496614 cites W1541582222 @default.
• W4280496614 cites W1881181639 @default.
• W4280496614 cites W1901260206 @default.
• W4280496614 cites W1957708244 @default.
• W4280496614 cites W1978379118 @default.
• W4280496614 cites W1997117942 @default.
• W4280496614 cites W2005282068 @default.
• W4280496614 cites W2007791604 @default.
• W4280496614 cites W2008133587 @default.
• W4280496614 cites W2060518203 @default.
• W4280496614 cites W2159431069 @default.
• W4280496614 cites W2160820922 @default.
• W4280496614 cites W2162289116 @default.
• W4280496614 cites W2254889102 @default.
• W4280496614 cites W2411898078 @default.
• W4280496614 cites W2417467881 @default.
• W4280496614 cites W2563529338 @default.
• W4280496614 cites W2609172362 @default.
• W4280496614 cites W2732410600 @default.
• W4280496614 cites W2765328875 @default.
• W4280496614 cites W2787093256 @default.
• W4280496614 cites W2789545474 @default.
• W4280496614 cites W2803277235 @default.
• W4280496614 cites W2888150073 @default.
• W4280496614 cites W2978689864 @default.
• W4280496614 cites W3011639403 @default.
• W4280496614 cites W3015863628 @default.
• W4280496614 cites W3106341933 @default.
• W4280496614 cites W3127778122 @default.
• W4280496614 cites W3197014581 @default.
• W4280496614 doi "https://doi.org/10.1016/j.ynpai.2022.100093" @default.
• W4280496614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35733704" @default.
• W4280496614 hasPublicationYear "2022" @default.
• W4280496614 type Work @default.
• W4280496614 citedByCount "3" @default.
• W4280496614 countsByYear W42804966142023 @default.
• W4280496614 crossrefType "journal-article" @default.
• W4280496614 hasAuthorship W4280496614A5005337452 @default.
• W4280496614 hasAuthorship W4280496614A5007089860 @default.
• W4280496614 hasAuthorship W4280496614A5011260334 @default.
• W4280496614 hasAuthorship W4280496614A5026641838 @default.
• W4280496614 hasAuthorship W4280496614A5029251642 @default.
• W4280496614 hasAuthorship W4280496614A5031538608 @default.
• W4280496614 hasAuthorship W4280496614A5034311774 @default.
• W4280496614 hasAuthorship W4280496614A5035118592 @default.
• W4280496614 hasAuthorship W4280496614A5040714412 @default.
• W4280496614 hasAuthorship W4280496614A5057767458 @default.
• W4280496614 hasAuthorship W4280496614A5059688748 @default.
• W4280496614 hasAuthorship W4280496614A5059772146 @default.
• W4280496614 hasAuthorship W4280496614A5081665529 @default.
• W4280496614 hasBestOaLocation W42804966141 @default.
• W4280496614 hasConcept C104996578 @default.
• W4280496614 hasConcept C126322002 @default.
• W4280496614 hasConcept C126838900 @default.
• W4280496614 hasConcept C143409427 @default.
• W4280496614 hasConcept C15744967 @default.
• W4280496614 hasConcept C169760540 @default.
• W4280496614 hasConcept C2777831278 @default.
• W4280496614 hasConcept C2779226451 @default.
• W4280496614 hasConcept C2780608534 @default.
• W4280496614 hasConcept C2781441883 @default.
• W4280496614 hasConcept C42219234 @default.
• W4280496614 hasConcept C71924100 @default.
• W4280496614 hasConceptScore W4280496614C104996578 @default.
• W4280496614 hasConceptScore W4280496614C126322002 @default.
• W4280496614 hasConceptScore W4280496614C126838900 @default.
• W4280496614 hasConceptScore W4280496614C143409427 @default.
• W4280496614 hasConceptScore W4280496614C15744967 @default.
• W4280496614 hasConceptScore W4280496614C169760540 @default.
• W4280496614 hasConceptScore W4280496614C2777831278 @default.
• W4280496614 hasConceptScore W4280496614C2779226451 @default.
• W4280496614 hasConceptScore W4280496614C2780608534 @default.
• W4280496614 hasConceptScore W4280496614C2781441883 @default.
• W4280496614 hasConceptScore W4280496614C42219234 @default.
• W4280496614 hasConceptScore W4280496614C71924100 @default.
• W4280496614 hasFunder F4320332403 @default.
• W4280496614 hasLocation W42804966141 @default.
• W4280496614 hasLocation W42804966142 @default.
• W4280496614 hasLocation W42804966143 @default.
• W4280496614 hasLocation W42804966144 @default.

• next