Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280496835> ?p ?o ?g. }
- W4280496835 endingPage "110835" @default.
- W4280496835 startingPage "110835" @default.
- W4280496835 abstract "Caloric restriction is a robust intervention to increase lifespan. Giving less food (calorie restriction [CR]) or allowing free access to a diluted diet with indigestible components (calorie dilution [CD]) are two methods to impose restriction. CD does not generate the same lifespan effect as CR. We compare responses of C57BL/6 mice with equivalent levels of CR and CD. The two groups have different responses in fat loss, circulating hormones, and metabolic rate. CR mice are hungrier, as assessed by behavioral assays. Although gene expression of Npy, Agrp, and Pomc do not differ between CR and CD groups, CR mice had a distinctive hypothalamic gene-expression profile with many genes related to starvation upregulated relative to CD. While both result in lower calorie intake, CR and CD are not equivalent procedures. Increased hunger under CR supports the hypothesis that hunger signaling is a key process mediating the benefits of CR." @default.
- W4280496835 created "2022-05-22" @default.
- W4280496835 creator A5022065302 @default.
- W4280496835 creator A5027475930 @default.
- W4280496835 creator A5051265138 @default.
- W4280496835 creator A5052024256 @default.
- W4280496835 creator A5056178986 @default.
- W4280496835 creator A5075827151 @default.
- W4280496835 creator A5077901649 @default.
- W4280496835 creator A5085888597 @default.
- W4280496835 date "2022-05-01" @default.
- W4280496835 modified "2023-10-03" @default.
- W4280496835 title "Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression" @default.
- W4280496835 cites W1491201523 @default.
- W4280496835 cites W1502228276 @default.
- W4280496835 cites W1557400022 @default.
- W4280496835 cites W1901983160 @default.
- W4280496835 cites W1965780343 @default.
- W4280496835 cites W1975198322 @default.
- W4280496835 cites W1984151407 @default.
- W4280496835 cites W1995384855 @default.
- W4280496835 cites W1996888905 @default.
- W4280496835 cites W1998660601 @default.
- W4280496835 cites W1998781513 @default.
- W4280496835 cites W1998973957 @default.
- W4280496835 cites W2014689033 @default.
- W4280496835 cites W2015084556 @default.
- W4280496835 cites W2016797892 @default.
- W4280496835 cites W2018508671 @default.
- W4280496835 cites W2027867105 @default.
- W4280496835 cites W2042438674 @default.
- W4280496835 cites W2043738446 @default.
- W4280496835 cites W2051945197 @default.
- W4280496835 cites W2053949211 @default.
- W4280496835 cites W2060629038 @default.
- W4280496835 cites W2063109626 @default.
- W4280496835 cites W2064053635 @default.
- W4280496835 cites W2064958921 @default.
- W4280496835 cites W2081290867 @default.
- W4280496835 cites W2087882709 @default.
- W4280496835 cites W2104438296 @default.
- W4280496835 cites W2112733614 @default.
- W4280496835 cites W2114104545 @default.
- W4280496835 cites W2117879192 @default.
- W4280496835 cites W2119441851 @default.
- W4280496835 cites W2131193972 @default.
- W4280496835 cites W2134191062 @default.
- W4280496835 cites W2136317611 @default.
- W4280496835 cites W2138207763 @default.
- W4280496835 cites W2142228799 @default.
- W4280496835 cites W2146148855 @default.
- W4280496835 cites W2148622539 @default.
- W4280496835 cites W2149403100 @default.
- W4280496835 cites W2155408559 @default.
- W4280496835 cites W2155892659 @default.
- W4280496835 cites W2166492500 @default.
- W4280496835 cites W2167222546 @default.
- W4280496835 cites W2170011943 @default.
- W4280496835 cites W2259671936 @default.
- W4280496835 cites W2296240596 @default.
- W4280496835 cites W2297798471 @default.
- W4280496835 cites W2310628435 @default.
- W4280496835 cites W2340324006 @default.
- W4280496835 cites W2399712251 @default.
- W4280496835 cites W2414259291 @default.
- W4280496835 cites W2421296032 @default.
- W4280496835 cites W2577597748 @default.
- W4280496835 cites W2587786087 @default.
- W4280496835 cites W2787946920 @default.
- W4280496835 cites W2795818534 @default.
- W4280496835 cites W2918397108 @default.
- W4280496835 cites W2932956381 @default.
- W4280496835 cites W2964849163 @default.
- W4280496835 cites W3006923990 @default.
- W4280496835 cites W3009892799 @default.
- W4280496835 cites W3023202069 @default.
- W4280496835 cites W3041584383 @default.
- W4280496835 cites W3087214315 @default.
- W4280496835 cites W3193007653 @default.
- W4280496835 cites W3205401845 @default.
- W4280496835 cites W4211127285 @default.
- W4280496835 doi "https://doi.org/10.1016/j.celrep.2022.110835" @default.
- W4280496835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35584669" @default.
- W4280496835 hasPublicationYear "2022" @default.
- W4280496835 type Work @default.
- W4280496835 citedByCount "6" @default.
- W4280496835 countsByYear W42804968352022 @default.
- W4280496835 countsByYear W42804968352023 @default.
- W4280496835 crossrefType "journal-article" @default.
- W4280496835 hasAuthorship W4280496835A5022065302 @default.
- W4280496835 hasAuthorship W4280496835A5027475930 @default.
- W4280496835 hasAuthorship W4280496835A5051265138 @default.
- W4280496835 hasAuthorship W4280496835A5052024256 @default.
- W4280496835 hasAuthorship W4280496835A5056178986 @default.
- W4280496835 hasAuthorship W4280496835A5075827151 @default.
- W4280496835 hasAuthorship W4280496835A5077901649 @default.
- W4280496835 hasAuthorship W4280496835A5085888597 @default.
- W4280496835 hasBestOaLocation W42804968351 @default.