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- W4280496892 endingPage "2052" @default.
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- W4280496892 abstract "Abstract The additive‐free 1,3‐dipolar cycloaddition reaction of isatin‐derived azomethine ylides with α‐cyano‐α,β‐unsaturated compounds was developed, which enabled diversity‐oriented synthesis of a series of novel and structurally complex 3,3′‐pyrrolidinyl‐spirooxindoles derivatives containing four contiguous and two quaternary stereogenic centers in high yields (up to 92%) and excellent diastereoselectivities (up to >25:1 dr). The reaction displays switchable regioselectivity depending on the steric effect of the substrates. magnified image" @default.
- W4280496892 created "2022-05-22" @default.
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- W4280496892 date "2022-05-20" @default.
- W4280496892 modified "2023-10-02" @default.
- W4280496892 title "Substrate‐Controlled Regioselectivity Switch in a Three‐Component 1,3‐Dipolar Cycloaddition Reaction to Access 3,3′‐Pyrrolidinyl‐Spirooxindoles Derivatives" @default.
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- W4280496892 doi "https://doi.org/10.1002/adsc.202200269" @default.
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