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• W4280497981 abstract "New tetrahydropyrazino[2,3-c]quinolin-5(6H)-ones were prepared from 3-chloroquinoline-2,4(1H,3H)-diones and ethylene diamine. In their reaction with HNCO, an unprecedented molecular rearrangement produced new types of hydantoin derivatives. All prepared compounds were characterized on the basis of their 1H, 13C, and 15N NMR and ESI mass spectra and some were authenticated by X-ray analysis of single crystalline material. A proposed mechanism for rearrangement is discussed in this essay. The CDK and ABL inhibition activity as well as in vitro cytotoxicity of the prepared compounds was also tested." @default.
• W4280497981 created "2022-05-22" @default.
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• W4280497981 date "2022-05-13" @default.
• W4280497981 modified "2023-10-06" @default.
• W4280497981 title "Molecular Rearrangement of Pyrazino[2,3-c]quinolin-5(6H)-ones during Their Reaction with Isocyanic Acid" @default.
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• W4280497981 doi "https://doi.org/10.3390/ijms23105481" @default.
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