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- W4280502143 abstract "The proposed pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) mainly includes ischemia and neuroinflammation mechanisms. Protein encoded by Proteoglycan 2 (PRG2) mRNA is involved in the immune process related to eosinophils, also being found in the placenta and peripheral blood of pregnant women. We evaluated the correlation between PRG2 and NPSLE for the first time and found that PRG2 protein was overexpressed in the serum of patients with NPSLE and correlated with the SLE disease activity index (SLEDAI) subset scores of psychosis. Moreover, we investigated the correlation between hippocampal PRG2 level and hippocampally dependent learning and memory ability in MRL/lpr mice, and discovered that the number of PRG2+GFAP+ astrocytes in the cortex and hypothalamus and the number of PRG2+IBA-1+ microglia in the hippocampus and cortex significantly increased in the MRL/lpr mice. These data provided a reference for the follow-up exploration of the role of PRG2 in SLE or other diseases." @default.
- W4280502143 created "2022-05-22" @default.
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- W4280502143 date "2022-06-01" @default.
- W4280502143 modified "2023-09-27" @default.
- W4280502143 title "The correlation between proteoglycan 2 and neuropsychiatric systemic lupus erythematosus" @default.
- W4280502143 cites W1543172895 @default.
- W4280502143 cites W1546923829 @default.
- W4280502143 cites W1582175554 @default.
- W4280502143 cites W1600697457 @default.
- W4280502143 cites W1671018864 @default.
- W4280502143 cites W1840906208 @default.
- W4280502143 cites W1958714009 @default.
- W4280502143 cites W1958716837 @default.
- W4280502143 cites W1973798645 @default.
- W4280502143 cites W1979283544 @default.
- W4280502143 cites W1982765876 @default.
- W4280502143 cites W1988353820 @default.
- W4280502143 cites W1989335453 @default.
- W4280502143 cites W1994580609 @default.
- W4280502143 cites W1995262615 @default.
- W4280502143 cites W1996353737 @default.
- W4280502143 cites W2039809246 @default.
- W4280502143 cites W2042285548 @default.
- W4280502143 cites W2042847262 @default.
- W4280502143 cites W2044761411 @default.
- W4280502143 cites W2047829740 @default.
- W4280502143 cites W2049426078 @default.
- W4280502143 cites W2060688692 @default.
- W4280502143 cites W2060730281 @default.
- W4280502143 cites W2061184447 @default.
- W4280502143 cites W2063925508 @default.
- W4280502143 cites W2064974599 @default.
- W4280502143 cites W2079279399 @default.
- W4280502143 cites W2087953568 @default.
- W4280502143 cites W2093548393 @default.
- W4280502143 cites W2093934913 @default.
- W4280502143 cites W2096604601 @default.
- W4280502143 cites W2101035994 @default.
- W4280502143 cites W2124550177 @default.
- W4280502143 cites W2128551987 @default.
- W4280502143 cites W2136239275 @default.
- W4280502143 cites W2140942460 @default.
- W4280502143 cites W2156054974 @default.
- W4280502143 cites W2156309972 @default.
- W4280502143 cites W2162909320 @default.
- W4280502143 cites W2164877789 @default.
- W4280502143 cites W2176745654 @default.
- W4280502143 cites W2306426915 @default.
- W4280502143 cites W2343541505 @default.
- W4280502143 cites W2344929719 @default.
- W4280502143 cites W2561536790 @default.
- W4280502143 cites W2582494666 @default.
- W4280502143 cites W2597563735 @default.
- W4280502143 cites W2597677763 @default.
- W4280502143 cites W2737015514 @default.
- W4280502143 cites W2751610678 @default.
- W4280502143 cites W2758521966 @default.
- W4280502143 cites W2766936425 @default.
- W4280502143 cites W2808655956 @default.
- W4280502143 cites W2894160329 @default.
- W4280502143 cites W2909620196 @default.
- W4280502143 cites W2968019161 @default.
- W4280502143 cites W2969002020 @default.
- W4280502143 cites W2972747213 @default.
- W4280502143 cites W2975555531 @default.
- W4280502143 cites W2979936029 @default.
- W4280502143 cites W2991129226 @default.
- W4280502143 cites W3001760694 @default.
- W4280502143 cites W3006502728 @default.
- W4280502143 cites W3008105794 @default.
- W4280502143 cites W3010621761 @default.
- W4280502143 cites W3022636047 @default.
- W4280502143 cites W3032927662 @default.
- W4280502143 cites W3044145717 @default.
- W4280502143 cites W3096116308 @default.
- W4280502143 cites W3096819689 @default.
- W4280502143 cites W3100496000 @default.
- W4280502143 cites W3110711499 @default.
- W4280502143 cites W3111116682 @default.
- W4280502143 cites W3134023604 @default.
- W4280502143 cites W3163002440 @default.
- W4280502143 cites W3164292949 @default.
- W4280502143 cites W3189089025 @default.
- W4280502143 cites W3196415230 @default.
- W4280502143 cites W4211021876 @default.
- W4280502143 cites W4361798048 @default.
- W4280502143 doi "https://doi.org/10.1016/j.clim.2022.109042" @default.
- W4280502143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35568106" @default.
- W4280502143 hasPublicationYear "2022" @default.