FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280508788> ?p ?o ?g. }

• W4280508788 abstract "Primates have evolved a variety of feeding habits and intestinal physiological structure. Gut microbiome act as metabolic organs in many biological processes and play a vital role in adaptation to dietary niches. Gut microbiome also convert primary bile acids (BAs) to secondary. BAs profile and gut microbiome are together influenced by diets and play a significant role in nutrient absorption. The regulation between gut microbiome and BAs metabolism is bidirectional although the relationship in primates consuming diverse diets is still unclear. Here, we investigated gut microbiome structures, fecal BAs profile, and their relationship in primates preferring three distinct diets. We found that gut microbiome communities are well differentiated among dietary groups. Folivorous primates had higher Firmicutes abundance and lower Prevotella to Bacaeroides ratios, possibly related to fiber consumption. Frugivorous primates are colonized predominantly by Prevotella and Bacteroides, pointing to an increased adaptation to high-sugar and simple carbohydrate diets. Likewise, BA profiles differ according to diet in a manner predictable from the known effects of BAs on metabolism. Folivorous primates have high conjugated bile acid levels and low unconjugated to conjugated BA ratios, consistent with their fiber-rich leaf-eating diet. Much of the differentiation in secondary and unconjugated BAs is associated with microbiome composition shifts and individual bile acid concentrations are correlated with the abundance of distinct bacterial taxonomic groups. Omnivores have higher concentrations of secondary BAs, mainly lithocholic acid (LCA). These levels are significantly positively correlated with the presence of Clostrida species, showing that the digestion requirements of omnivores are different from plant-eating primates. In conclusion, gut microbiome and BAs can respond to changes in diet and are associated with nutrient component consumption in each diet primate group. Our study is the first to demonstrate BA profile differentiation among primates preferring diverse diets. BAs thus appear to work with gut microbiome to help primates adapt to their diet." @default.
• W4280508788 created "2022-05-22" @default.
• W4280508788 creator A5000010862 @default.
• W4280508788 creator A5005426960 @default.
• W4280508788 creator A5021384155 @default.
• W4280508788 creator A5024541563 @default.
• W4280508788 creator A5027369269 @default.
• W4280508788 creator A5052675433 @default.
• W4280508788 creator A5084120665 @default.
• W4280508788 creator A5088579118 @default.
• W4280508788 date "2022-05-11" @default.
• W4280508788 modified "2023-10-01" @default.
• W4280508788 title "The Relationship Between Gut Microbiome and Bile Acids in Primates With Diverse Diets" @default.
• W4280508788 cites W1522859009 @default.
• W4280508788 cites W1974616640 @default.
• W4280508788 cites W2027048436 @default.
• W4280508788 cites W2045204781 @default.
• W4280508788 cites W2049169935 @default.
• W4280508788 cites W2053312881 @default.
• W4280508788 cites W2061558768 @default.
• W4280508788 cites W2062551369 @default.
• W4280508788 cites W2066507296 @default.
• W4280508788 cites W2079166934 @default.
• W4280508788 cites W2084669296 @default.
• W4280508788 cites W2093095120 @default.
• W4280508788 cites W2097136349 @default.
• W4280508788 cites W2103878237 @default.
• W4280508788 cites W2104891233 @default.
• W4280508788 cites W2110175600 @default.
• W4280508788 cites W2110256992 @default.
• W4280508788 cites W2113679889 @default.
• W4280508788 cites W2123561714 @default.
• W4280508788 cites W2129362189 @default.
• W4280508788 cites W2131271579 @default.
• W4280508788 cites W2134897177 @default.
• W4280508788 cites W2154311481 @default.
• W4280508788 cites W2155929342 @default.
• W4280508788 cites W2162904770 @default.
• W4280508788 cites W2167062509 @default.
• W4280508788 cites W2170551349 @default.
• W4280508788 cites W2292760617 @default.
• W4280508788 cites W2428595929 @default.
• W4280508788 cites W2559045472 @default.
• W4280508788 cites W2616825195 @default.
• W4280508788 cites W2620275008 @default.
• W4280508788 cites W2765207178 @default.
• W4280508788 cites W2765565527 @default.
• W4280508788 cites W2800508649 @default.
• W4280508788 cites W2806610369 @default.
• W4280508788 cites W2896446765 @default.
• W4280508788 cites W2903267537 @default.
• W4280508788 cites W2915404637 @default.
• W4280508788 cites W2920716817 @default.
• W4280508788 cites W2921460411 @default.
• W4280508788 cites W2924978408 @default.
• W4280508788 cites W2937762618 @default.
• W4280508788 cites W2941278429 @default.
• W4280508788 cites W2945309425 @default.
• W4280508788 cites W2949260349 @default.
• W4280508788 cites W2955286056 @default.
• W4280508788 cites W2963132797 @default.
• W4280508788 cites W2965321915 @default.
• W4280508788 cites W2970178875 @default.
• W4280508788 cites W2972775825 @default.
• W4280508788 cites W2976354416 @default.
• W4280508788 cites W2979675761 @default.
• W4280508788 cites W2993955438 @default.
• W4280508788 cites W2995308611 @default.
• W4280508788 cites W3006266099 @default.
• W4280508788 cites W3014528243 @default.
• W4280508788 cites W3042688774 @default.
• W4280508788 cites W3092880929 @default.
• W4280508788 cites W3124213695 @default.
• W4280508788 cites W3133909759 @default.
• W4280508788 cites W3136914940 @default.
• W4280508788 cites W3184541229 @default.
• W4280508788 cites W3198649369 @default.
• W4280508788 cites W3205971043 @default.
• W4280508788 cites W4221131751 @default.
• W4280508788 doi "https://doi.org/10.3389/fmicb.2022.899102" @default.
• W4280508788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35633689" @default.
• W4280508788 hasPublicationYear "2022" @default.
• W4280508788 type Work @default.
• W4280508788 citedByCount "3" @default.
• W4280508788 countsByYear W42805087882023 @default.
• W4280508788 crossrefType "journal-article" @default.
• W4280508788 hasAuthorship W4280508788A5000010862 @default.
• W4280508788 hasAuthorship W4280508788A5005426960 @default.
• W4280508788 hasAuthorship W4280508788A5021384155 @default.
• W4280508788 hasAuthorship W4280508788A5024541563 @default.
• W4280508788 hasAuthorship W4280508788A5027369269 @default.
• W4280508788 hasAuthorship W4280508788A5052675433 @default.
• W4280508788 hasAuthorship W4280508788A5084120665 @default.
• W4280508788 hasAuthorship W4280508788A5088579118 @default.
• W4280508788 hasBestOaLocation W42805087881 @default.
• W4280508788 hasConcept C104317684 @default.
• W4280508788 hasConcept C11796040 @default.
• W4280508788 hasConcept C132050396 @default.
• W4280508788 hasConcept C139807058 @default.
• W4280508788 hasConcept C143121216 @default.

• next