FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280518465> ?p ?o ?g. }

• W4280518465 abstract "Abstract The use of stable isotope tracers and mass spectrometry (MS) is the gold standard method for the analysis of fatty acids (FAs) metabolism. Yet current state-of-the-art tools provide limited and difficult to interpret information about FA biosynthetic routes. Here we present FAMetA, an R-package and a web-based application ( www.fameta.es ) that use 13 C mass-isotopologue profiles to estimate FA import, de novo lipogenesis, elongation, and desaturation in a user-friendly platform. The FAMetA workflow covers all the functionalities needed for MS data analyses. To illustrate its utility, different in vitro and in vivo experimental settings are used in which FA metabolism is modified. Thanks to the comprehensive characterisation of FA biosynthesis and the easy-to-interpret graphical representations compared to previous tools, FAMetA discloses unnoticed insights into how cells reprogramme their FA metabolism and, when combined with FASN, SCD1 and FADS2 inhibitors, it enables the straightforward identification of new FAs by the metabolic reconstruction of their synthesis route." @default.
• W4280518465 created "2022-05-22" @default.
• W4280518465 creator A5008290108 @default.
• W4280518465 creator A5050185043 @default.
• W4280518465 creator A5069744255 @default.
• W4280518465 creator A5083933505 @default.
• W4280518465 creator A5084368873 @default.
• W4280518465 date "2022-05-11" @default.
• W4280518465 modified "2023-10-14" @default.
• W4280518465 title "FAMetA: a mass isotopologue-based tool for the comprehensive analysis of fatty acid metabolism" @default.
• W4280518465 cites W1553155385 @default.
• W4280518465 cites W1577451703 @default.
• W4280518465 cites W1631264919 @default.
• W4280518465 cites W1862881433 @default.
• W4280518465 cites W1876867591 @default.
• W4280518465 cites W1965671023 @default.
• W4280518465 cites W1980206386 @default.
• W4280518465 cites W1980244201 @default.
• W4280518465 cites W1985380245 @default.
• W4280518465 cites W1985399572 @default.
• W4280518465 cites W1997085730 @default.
• W4280518465 cites W2012216316 @default.
• W4280518465 cites W2013033098 @default.
• W4280518465 cites W2014323212 @default.
• W4280518465 cites W2015012139 @default.
• W4280518465 cites W2045530900 @default.
• W4280518465 cites W2081465448 @default.
• W4280518465 cites W2116516144 @default.
• W4280518465 cites W2126711569 @default.
• W4280518465 cites W2137386173 @default.
• W4280518465 cites W2168347591 @default.
• W4280518465 cites W2170888045 @default.
• W4280518465 cites W2173687180 @default.
• W4280518465 cites W2174983526 @default.
• W4280518465 cites W2281483562 @default.
• W4280518465 cites W2560396365 @default.
• W4280518465 cites W2610435987 @default.
• W4280518465 cites W2754309346 @default.
• W4280518465 cites W2796927648 @default.
• W4280518465 cites W2810629608 @default.
• W4280518465 cites W2902607424 @default.
• W4280518465 cites W2902859004 @default.
• W4280518465 cites W2913095286 @default.
• W4280518465 cites W2936706033 @default.
• W4280518465 cites W2945039203 @default.
• W4280518465 cites W2952632749 @default.
• W4280518465 cites W2971788324 @default.
• W4280518465 cites W3022743377 @default.
• W4280518465 cites W3023443595 @default.
• W4280518465 cites W3036373725 @default.
• W4280518465 cites W3127764969 @default.
• W4280518465 cites W3129132895 @default.
• W4280518465 cites W3151637556 @default.
• W4280518465 cites W3157598024 @default.
• W4280518465 cites W3170001590 @default.
• W4280518465 cites W3184325305 @default.
• W4280518465 cites W3197143861 @default.
• W4280518465 cites W4205283001 @default.
• W4280518465 cites W4214630651 @default.
• W4280518465 doi "https://doi.org/10.1101/2022.05.11.491462" @default.
• W4280518465 hasPublicationYear "2022" @default.
• W4280518465 type Work @default.
• W4280518465 citedByCount "0" @default.
• W4280518465 crossrefType "posted-content" @default.
• W4280518465 hasAuthorship W4280518465A5008290108 @default.
• W4280518465 hasAuthorship W4280518465A5050185043 @default.
• W4280518465 hasAuthorship W4280518465A5069744255 @default.
• W4280518465 hasAuthorship W4280518465A5083933505 @default.
• W4280518465 hasAuthorship W4280518465A5084368873 @default.
• W4280518465 hasBestOaLocation W42805184651 @default.
• W4280518465 hasConcept C13934619 @default.
• W4280518465 hasConcept C141359234 @default.
• W4280518465 hasConcept C162356407 @default.
• W4280518465 hasConcept C177212765 @default.
• W4280518465 hasConcept C178790620 @default.
• W4280518465 hasConcept C185592680 @default.
• W4280518465 hasConcept C2776991927 @default.
• W4280518465 hasConcept C32909587 @default.
• W4280518465 hasConcept C41008148 @default.
• W4280518465 hasConcept C43617362 @default.
• W4280518465 hasConcept C543025807 @default.
• W4280518465 hasConcept C55493867 @default.
• W4280518465 hasConcept C62231903 @default.
• W4280518465 hasConcept C70721500 @default.
• W4280518465 hasConcept C77088390 @default.
• W4280518465 hasConcept C86803240 @default.
• W4280518465 hasConceptScore W4280518465C13934619 @default.
• W4280518465 hasConceptScore W4280518465C141359234 @default.
• W4280518465 hasConceptScore W4280518465C162356407 @default.
• W4280518465 hasConceptScore W4280518465C177212765 @default.
• W4280518465 hasConceptScore W4280518465C178790620 @default.
• W4280518465 hasConceptScore W4280518465C185592680 @default.
• W4280518465 hasConceptScore W4280518465C2776991927 @default.
• W4280518465 hasConceptScore W4280518465C32909587 @default.
• W4280518465 hasConceptScore W4280518465C41008148 @default.
• W4280518465 hasConceptScore W4280518465C43617362 @default.
• W4280518465 hasConceptScore W4280518465C543025807 @default.
• W4280518465 hasConceptScore W4280518465C55493867 @default.
• W4280518465 hasConceptScore W4280518465C62231903 @default.
• W4280518465 hasConceptScore W4280518465C70721500 @default.

• next