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- W4280520131 abstract "<b><i>Background:</i></b> The combination of acute myocardial infarction (AMI) and atrial fibrillation (AF) is still a thorny problem in the clinic. At present, there are few reports on the role of soluble suppression of tumorigenicity 2 (sST2) in AF after AMI. This study was to explore the predictive value of sST2 in patients with AMI for new-onset AF. <b><i>Methods:</i></b> This is a single-center retrospective clinical observation study. We continuously included AMI patients from September 2019 to November 2021. The concentration of sST2 in blood samples was determined. During admission, a suspicious heart rhythm was recorded by electrocardiogram (ECG) monitoring, and new-onset AF was confirmed by immediate body surface ECG. <b><i>Results:</i></b> After multiple factors were included, age, right coronary artery, high-sensitivity C-reactive protein, left ventricular ejection fraction, and sST2 were still risk factors for new-onset AF. The area under curve value of age and sST2 was more than 0.7, which showed good diagnostic value. For reevaluation, the sST2 was added to the clinical new-onset AF prediction model. It was found that the integrated discrimination improvement and net reclassification index in the model were improved significantly. <b><i>Conclusion:</i></b> sST2 is an independent predictor of new-onset AF in patients with AMI and can improve the accuracy of the AF risk model." @default.
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- W4280520131 date "2022-01-01" @default.
- W4280520131 modified "2023-10-16" @default.
- W4280520131 title "Association of Soluble Suppression of Tumorigenicity 2 with New-Onset Atrial Fibrillation in Acute Myocardial Infarction" @default.
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- W4280520131 doi "https://doi.org/10.1159/000524765" @default.
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