FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280521716> ?p ?o ?g. }

• W4280521716 abstract "Introduction Migraine and sleep share a complex and unclear relationship. Poor sleep may trigger migraine attacks; migraine, in turn, is frequently associated with sleep disorders. Few previous studies used questionnaires to assess sleep changes in patients who were treated with migraine-preventive medications (MPMs). More extensive polysomnography (PSG)-based studies for this purpose were not available. Objective To investigate possible sleep changes in patients with migraine treated with erenumab, using validated sleep questionnaires and home-PSG. Methods This observational, prospective, open-label pilot study was conducted at the Clinical Neurology Unit Headache Center of Udine University Hospital from 2020 to 2021. Patients were treated with erenumab as monotherapy or add-on treatment for migraine prevention. Sleep changes were evaluated with questionnaires and polysomnographic recordings at baseline, after 3 and 12 months of treatment. Erenumab efficacy and safety in migraine prophylaxis were also investigated. Results Twenty-nine patients completed 3 months of follow-up, whereas 15 patients completed 12 months. We found a weak trend of improvement in daytime somnolence after 3 months of treatment, with stronger results after 12 months (median Epworth Sleepiness Scale (ESS) score from 6.0 to 4.0, p = 0.015); a significant improvement in subjective sleep quality (median Pittsburgh Sleep Quality Index (PSQI) total score from 7 to 5; p = 0.001) was also observed. Home-PSG showed a significant increase in objective sleep efficiency (SE), both after 3 (from 88.1 to 91.0, p = 0.006) and 12 months (from 87.1 to 91.0, p = 0.006) of treatment. In addition, our data confirmed erenumab effectiveness and safety in migraine prevention. Conclusion Our study demonstrated an improvement in both subjective and objective sleep quality in patients treated with a migraine-preventive therapy. Erenumab, in particular, does not cross the blood-brain barrier (BBB), thus a direct effect on sleep is unlikely. Future studies are needed to better understand the mutual influence between migraine and sleep disorders." @default.
• W4280521716 created "2022-05-22" @default.
• W4280521716 creator A5005044418 @default.
• W4280521716 creator A5019911787 @default.
• W4280521716 creator A5030062010 @default.
• W4280521716 creator A5033368093 @default.
• W4280521716 creator A5040134654 @default.
• W4280521716 creator A5070093677 @default.
• W4280521716 creator A5091778912 @default.
• W4280521716 date "2022-05-13" @default.
• W4280521716 modified "2023-09-26" @default.
• W4280521716 title "Erenumab Impact on Sleep Assessed With Questionnaires and Home-Polysomnography in Patients With Migraine: The ERESON Study" @default.
• W4280521716 cites W1802284765 @default.
• W4280521716 cites W1824447908 @default.
• W4280521716 cites W1937674079 @default.
• W4280521716 cites W197066864 @default.
• W4280521716 cites W1975230079 @default.
• W4280521716 cites W1980575238 @default.
• W4280521716 cites W1986735808 @default.
• W4280521716 cites W1994966400 @default.
• W4280521716 cites W2002293846 @default.
• W4280521716 cites W2006472378 @default.
• W4280521716 cites W2013622850 @default.
• W4280521716 cites W2017537770 @default.
• W4280521716 cites W2023073151 @default.
• W4280521716 cites W2036308543 @default.
• W4280521716 cites W204766049 @default.
• W4280521716 cites W2049326326 @default.
• W4280521716 cites W2052341728 @default.
• W4280521716 cites W2066528902 @default.
• W4280521716 cites W2066799036 @default.
• W4280521716 cites W2073160193 @default.
• W4280521716 cites W2078619082 @default.
• W4280521716 cites W2084151466 @default.
• W4280521716 cites W2105059392 @default.
• W4280521716 cites W2116410539 @default.
• W4280521716 cites W2129181629 @default.
• W4280521716 cites W2151487996 @default.
• W4280521716 cites W2152418723 @default.
• W4280521716 cites W2155291849 @default.
• W4280521716 cites W2167183660 @default.
• W4280521716 cites W2183799972 @default.
• W4280521716 cites W2273601764 @default.
• W4280521716 cites W2473786944 @default.
• W4280521716 cites W2496174529 @default.
• W4280521716 cites W2556984422 @default.
• W4280521716 cites W2626067817 @default.
• W4280521716 cites W2742914855 @default.
• W4280521716 cites W2755886318 @default.
• W4280521716 cites W2760901533 @default.
• W4280521716 cites W2794469711 @default.
• W4280521716 cites W2801085490 @default.
• W4280521716 cites W2801232260 @default.
• W4280521716 cites W2885081480 @default.
• W4280521716 cites W2887418188 @default.
• W4280521716 cites W2897136351 @default.
• W4280521716 cites W2910809224 @default.
• W4280521716 cites W2922174162 @default.
• W4280521716 cites W2948005364 @default.
• W4280521716 cites W2994185727 @default.
• W4280521716 cites W2997725658 @default.
• W4280521716 cites W3013178006 @default.
• W4280521716 cites W3015052705 @default.
• W4280521716 cites W3033647323 @default.
• W4280521716 cites W3096801904 @default.
• W4280521716 cites W3120635632 @default.
• W4280521716 cites W3128399541 @default.
• W4280521716 cites W3164805530 @default.
• W4280521716 cites W3201466718 @default.
• W4280521716 cites W3203896952 @default.
• W4280521716 cites W4244823958 @default.
• W4280521716 cites W4254908862 @default.
• W4280521716 cites W649176274 @default.
• W4280521716 doi "https://doi.org/10.3389/fneur.2022.869677" @default.
• W4280521716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35645951" @default.
• W4280521716 hasPublicationYear "2022" @default.
• W4280521716 type Work @default.
• W4280521716 citedByCount "2" @default.
• W4280521716 countsByYear W42805217162022 @default.
• W4280521716 countsByYear W42805217162023 @default.
• W4280521716 crossrefType "journal-article" @default.
• W4280521716 hasAuthorship W4280521716A5005044418 @default.
• W4280521716 hasAuthorship W4280521716A5019911787 @default.
• W4280521716 hasAuthorship W4280521716A5030062010 @default.
• W4280521716 hasAuthorship W4280521716A5033368093 @default.
• W4280521716 hasAuthorship W4280521716A5040134654 @default.
• W4280521716 hasAuthorship W4280521716A5070093677 @default.
• W4280521716 hasAuthorship W4280521716A5091778912 @default.
• W4280521716 hasBestOaLocation W42805217161 @default.
• W4280521716 hasConcept C111919701 @default.
• W4280521716 hasConcept C118552586 @default.
• W4280521716 hasConcept C126322002 @default.
• W4280521716 hasConcept C1513209611 @default.
• W4280521716 hasConcept C16568411 @default.
• W4280521716 hasConcept C1862650 @default.
• W4280521716 hasConcept C197934379 @default.
• W4280521716 hasConcept C2775841894 @default.
• W4280521716 hasConcept C2776245837 @default.
• W4280521716 hasConcept C2778205975 @default.
• W4280521716 hasConcept C2778541695 @default.

• next