Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280522076> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4280522076 endingPage "112473" @default.
- W4280522076 startingPage "112473" @default.
- W4280522076 abstract "Copper-based photosensitizer nanoparticle has high potential clinic translation potency for its extensive physiological effects such as anti-cancer progression, anti-bacteria and accelerate tissue regeneration. However, copper excess or improper coordination can induce toxicity or reduce drug efficacy. To get proper copper-photosensitizer complex nanoparticle, a portion of chlorin e6 covalently conjugated with low molecular weight fish collagen fragments-collage tripeptides (CTPs), and Cu2+ subsequently triggers CTP-Ce6 conjugates assemble to Cu(II) based CTP-Ce6 nanosphere(CCeC-Ns). CCeC-Ns are 10-20 nm nanoparticles. CCeC-Ns quenched Ce6 fluorescence in aqueous solution and improved longer wavelength light absorbance. It exhibited dramatically higher cellular uptake rates and much more anticancer potency than those of free Ce6 under 660 nm irradiation without obvious dark toxicity in vitro. CCeC-Ns have longer retention time and higher penetrating rate than free Ce6 in tumor spheroid model. CCeC-Ns displayed extremely higher anti-bacterial potency than free Ce6 and sustainable efficacy. It provides a more potent and safer nanodrug for cancer and infection treatment and an idea for highly efficient metal-photosensitizers complexes design." @default.
- W4280522076 created "2022-05-22" @default.
- W4280522076 creator A5024433963 @default.
- W4280522076 creator A5044170328 @default.
- W4280522076 creator A5054418515 @default.
- W4280522076 creator A5086418698 @default.
- W4280522076 date "2022-07-01" @default.
- W4280522076 modified "2023-10-06" @default.
- W4280522076 title "Copper(II) based low molecular weight collagen fragments-chlorin e6 nanoparticles synergize anti-cancer and anti-bacteria photodynamic therapy" @default.
- W4280522076 cites W1966315709 @default.
- W4280522076 cites W2025424398 @default.
- W4280522076 cites W2071311986 @default.
- W4280522076 cites W2162153596 @default.
- W4280522076 cites W2321809554 @default.
- W4280522076 cites W2331216842 @default.
- W4280522076 cites W2793401247 @default.
- W4280522076 cites W2887202105 @default.
- W4280522076 cites W2909900419 @default.
- W4280522076 cites W2948231961 @default.
- W4280522076 cites W2954301652 @default.
- W4280522076 cites W2961164135 @default.
- W4280522076 cites W3017263212 @default.
- W4280522076 cites W3022716923 @default.
- W4280522076 cites W3033124744 @default.
- W4280522076 cites W3049411042 @default.
- W4280522076 cites W3082953595 @default.
- W4280522076 cites W3089289366 @default.
- W4280522076 cites W3151594924 @default.
- W4280522076 cites W3169940439 @default.
- W4280522076 cites W3207351371 @default.
- W4280522076 cites W3212636683 @default.
- W4280522076 cites W3215484928 @default.
- W4280522076 doi "https://doi.org/10.1016/j.jphotobiol.2022.112473" @default.
- W4280522076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35633609" @default.
- W4280522076 hasPublicationYear "2022" @default.
- W4280522076 type Work @default.
- W4280522076 citedByCount "3" @default.
- W4280522076 countsByYear W42805220762023 @default.
- W4280522076 crossrefType "journal-article" @default.
- W4280522076 hasAuthorship W4280522076A5024433963 @default.
- W4280522076 hasAuthorship W4280522076A5044170328 @default.
- W4280522076 hasAuthorship W4280522076A5054418515 @default.
- W4280522076 hasAuthorship W4280522076A5086418698 @default.
- W4280522076 hasConcept C12554922 @default.
- W4280522076 hasConcept C155672457 @default.
- W4280522076 hasConcept C171250308 @default.
- W4280522076 hasConcept C178790620 @default.
- W4280522076 hasConcept C185592680 @default.
- W4280522076 hasConcept C192562407 @default.
- W4280522076 hasConcept C202751555 @default.
- W4280522076 hasConcept C2778178086 @default.
- W4280522076 hasConcept C2781323092 @default.
- W4280522076 hasConcept C2781469039 @default.
- W4280522076 hasConcept C43617362 @default.
- W4280522076 hasConcept C544778455 @default.
- W4280522076 hasConcept C55493867 @default.
- W4280522076 hasConcept C57992300 @default.
- W4280522076 hasConcept C75473681 @default.
- W4280522076 hasConcept C86803240 @default.
- W4280522076 hasConcept C98015330 @default.
- W4280522076 hasConceptScore W4280522076C12554922 @default.
- W4280522076 hasConceptScore W4280522076C155672457 @default.
- W4280522076 hasConceptScore W4280522076C171250308 @default.
- W4280522076 hasConceptScore W4280522076C178790620 @default.
- W4280522076 hasConceptScore W4280522076C185592680 @default.
- W4280522076 hasConceptScore W4280522076C192562407 @default.
- W4280522076 hasConceptScore W4280522076C202751555 @default.
- W4280522076 hasConceptScore W4280522076C2778178086 @default.
- W4280522076 hasConceptScore W4280522076C2781323092 @default.
- W4280522076 hasConceptScore W4280522076C2781469039 @default.
- W4280522076 hasConceptScore W4280522076C43617362 @default.
- W4280522076 hasConceptScore W4280522076C544778455 @default.
- W4280522076 hasConceptScore W4280522076C55493867 @default.
- W4280522076 hasConceptScore W4280522076C57992300 @default.
- W4280522076 hasConceptScore W4280522076C75473681 @default.
- W4280522076 hasConceptScore W4280522076C86803240 @default.
- W4280522076 hasConceptScore W4280522076C98015330 @default.
- W4280522076 hasLocation W42805220761 @default.
- W4280522076 hasLocation W42805220762 @default.
- W4280522076 hasOpenAccess W4280522076 @default.
- W4280522076 hasPrimaryLocation W42805220761 @default.
- W4280522076 hasRelatedWork W2016578238 @default.
- W4280522076 hasRelatedWork W2140210736 @default.
- W4280522076 hasRelatedWork W2525054539 @default.
- W4280522076 hasRelatedWork W2529906967 @default.
- W4280522076 hasRelatedWork W2761343214 @default.
- W4280522076 hasRelatedWork W2791057600 @default.
- W4280522076 hasRelatedWork W2963416893 @default.
- W4280522076 hasRelatedWork W4225316135 @default.
- W4280522076 hasRelatedWork W4313260010 @default.
- W4280522076 hasRelatedWork W4379795636 @default.
- W4280522076 hasVolume "232" @default.
- W4280522076 isParatext "false" @default.
- W4280522076 isRetracted "false" @default.
- W4280522076 workType "article" @default.