FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280522425> ?p ?o ?g. }

• W4280522425 abstract "Abstract Relatives of individuals with schizophrenia have a higher risk of developing the illness compared to the general population. Thus, youth at familial high risk (FHR) offer a unique opportunity to identify neuroimaging-based endophenotypes of psychosis. Previous studies have identified lower amygdalo-hippocampal volume in FHR, as well as lower verbal memory and emotion recognition. However, whether these phenotypes increase the risk of transition to psychosis remains unclear. To determine if individuals who develop psychosis have abnormal neurodevelopmental trajectories of the amygdala and hippocampus, we investigated longitudinal changes of these structures in a unique cohort of 82 youth FHR and 56 healthy controls during a 3-year period. Ten individuals from the FHR group converted to psychosis. Longitudinal changes were compared using linear mixed-effects models. Group differences in verbal memory and emotion recognition performance at baseline were also analyzed. Surface-based morphometry measures revealed variation in amygdalar shape (concave shape of the right dorsomedial region) in those who converted to psychosis. Significantly lower emotion recognition performance at baseline was observed in converters. Percent trial-to-trial transfer on the verbal learning task was also significantly impaired in FHR, independently of the conversion status. Our results identify abnormal shape development trajectories in the dorsomedial amygdala and lower emotion recognition abilities as phenotypes of transition to psychosis. Our findings illustrate potential markers for early identification of psychosis, aiding prevention efforts in youth at risk of schizophrenia." @default.
• W4280522425 created "2022-05-22" @default.
• W4280522425 creator A5000706062 @default.
• W4280522425 creator A5016285763 @default.
• W4280522425 creator A5029578541 @default.
• W4280522425 creator A5045429640 @default.
• W4280522425 creator A5081706478 @default.
• W4280522425 date "2022-05-13" @default.
• W4280522425 modified "2023-10-17" @default.
• W4280522425 title "Altered amygdala shape trajectories and emotion recognition in youth at familial high risk of schizophrenia who develop psychosis" @default.
• W4280522425 cites W126950029 @default.
• W4280522425 cites W1876943069 @default.
• W4280522425 cites W1891773028 @default.
• W4280522425 cites W1955614066 @default.
• W4280522425 cites W1965146482 @default.
• W4280522425 cites W1966460145 @default.
• W4280522425 cites W1970006557 @default.
• W4280522425 cites W1970864734 @default.
• W4280522425 cites W1980548663 @default.
• W4280522425 cites W1983302342 @default.
• W4280522425 cites W1984173612 @default.
• W4280522425 cites W1994357726 @default.
• W4280522425 cites W2001696757 @default.
• W4280522425 cites W2008022914 @default.
• W4280522425 cites W2011481459 @default.
• W4280522425 cites W2012155259 @default.
• W4280522425 cites W2012289576 @default.
• W4280522425 cites W2017830745 @default.
• W4280522425 cites W2019416640 @default.
• W4280522425 cites W2024862721 @default.
• W4280522425 cites W2025945605 @default.
• W4280522425 cites W2034618400 @default.
• W4280522425 cites W2045310622 @default.
• W4280522425 cites W2053218327 @default.
• W4280522425 cites W2058233450 @default.
• W4280522425 cites W2059707257 @default.
• W4280522425 cites W2061996488 @default.
• W4280522425 cites W2070368610 @default.
• W4280522425 cites W2077115170 @default.
• W4280522425 cites W2085230397 @default.
• W4280522425 cites W2086826657 @default.
• W4280522425 cites W2089846607 @default.
• W4280522425 cites W2090902898 @default.
• W4280522425 cites W2098491858 @default.
• W4280522425 cites W2100728134 @default.
• W4280522425 cites W2104637120 @default.
• W4280522425 cites W2105527159 @default.
• W4280522425 cites W2112718139 @default.
• W4280522425 cites W2116532199 @default.
• W4280522425 cites W2127679160 @default.
• W4280522425 cites W2138270985 @default.
• W4280522425 cites W2150746895 @default.
• W4280522425 cites W2151295206 @default.
• W4280522425 cites W2156548928 @default.
• W4280522425 cites W2157964157 @default.
• W4280522425 cites W2161913873 @default.
• W4280522425 cites W2162950935 @default.
• W4280522425 cites W2165160891 @default.
• W4280522425 cites W2166739899 @default.
• W4280522425 cites W2170058394 @default.
• W4280522425 cites W2274252588 @default.
• W4280522425 cites W2278262299 @default.
• W4280522425 cites W2317568490 @default.
• W4280522425 cites W2518662868 @default.
• W4280522425 cites W2596331123 @default.
• W4280522425 cites W2609110050 @default.
• W4280522425 cites W2734560670 @default.
• W4280522425 cites W2743412037 @default.
• W4280522425 cites W2773029757 @default.
• W4280522425 cites W2970012504 @default.
• W4280522425 cites W331389127 @default.
• W4280522425 cites W4242640394 @default.
• W4280522425 cites W4248905700 @default.
• W4280522425 cites W4379191485 @default.
• W4280522425 doi "https://doi.org/10.1038/s41398-022-01957-3" @default.
• W4280522425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35562339" @default.
• W4280522425 hasPublicationYear "2022" @default.
• W4280522425 type Work @default.
• W4280522425 citedByCount "3" @default.
• W4280522425 countsByYear W42805224252022 @default.
• W4280522425 countsByYear W42805224252023 @default.
• W4280522425 crossrefType "journal-article" @default.
• W4280522425 hasAuthorship W4280522425A5000706062 @default.
• W4280522425 hasAuthorship W4280522425A5016285763 @default.
• W4280522425 hasAuthorship W4280522425A5029578541 @default.
• W4280522425 hasAuthorship W4280522425A5045429640 @default.
• W4280522425 hasAuthorship W4280522425A5081706478 @default.
• W4280522425 hasBestOaLocation W42805224251 @default.
• W4280522425 hasConcept C105641010 @default.
• W4280522425 hasConcept C118552586 @default.
• W4280522425 hasConcept C15744967 @default.
• W4280522425 hasConcept C169760540 @default.
• W4280522425 hasConcept C169900460 @default.
• W4280522425 hasConcept C187869287 @default.
• W4280522425 hasConcept C21963081 @default.
• W4280522425 hasConcept C2776412080 @default.
• W4280522425 hasConcept C2777727901 @default.
• W4280522425 hasConcept C2779144063 @default.
• W4280522425 hasConcept C2779727114 @default.
• W4280522425 hasConcept C2780292510 @default.

• next