Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280538049> ?p ?o ?g. }
- W4280538049 endingPage "7" @default.
- W4280538049 startingPage "1" @default.
- W4280538049 abstract "For the treatment and maintenance of postprandial blood glucose increases (i.e., diabetes mellitus), alpha (α)-amylase is a well-known therapeutic target. In this paper, we report an initial exploration of the work, i.e., in vitro alpha-amylase activity of the hydroalcoholic polyherbal extract of the selected plants. After drying, the plant material is ground individually, and at least 100 gm of the crude powder is prepared from each plant. 100 gm of each plant was combined, and a total of 500 gm of the crude powder (Ichnocarpus frutescens (100 gm) + Ficus dalhousie (100 gm) + Crateva magna (100 gm) + Alpinia galangal (100 gm) + Swertia chirata (100 gm)) was prepared to carry out the extraction. This obtained extract was subjected to preliminary phytochemical screening and in vitro alpha-amylase activity. At 16 mg/mL, acarbose displayed 78.40 ± 0.36% inhibition, whereas the extract exhibited 72.96 ± 0.70% inhibition, which is significantly comparable. The IC50 value of acarbose was 12.9 ± 1.12, whereas the extract exhibited 13.31 ± 1.12 mg/mL. The extract possesses numerous classes of chemicals such as alkaloids, glycosides, tannins, polyphenols, and terpenoids, which can contribute to the antidiabetic activity through alpha-amylase inhibition. This was an initial exploration of the work as a proof of concept for the development of polyherbal tea bag formulation for the treatment of diabetes. In the future, we are aiming to investigate the effectiveness of polyherbal tea bags in the treatment of diabetes using more in vitro and in vivo models. From the present investigation, we have concluded that this extract can be used for the treatment of diabetes." @default.
- W4280538049 created "2022-05-22" @default.
- W4280538049 creator A5016975298 @default.
- W4280538049 creator A5024563169 @default.
- W4280538049 creator A5044436618 @default.
- W4280538049 creator A5064102297 @default.
- W4280538049 creator A5064830000 @default.
- W4280538049 creator A5073155778 @default.
- W4280538049 creator A5079255688 @default.
- W4280538049 date "2022-05-12" @default.
- W4280538049 modified "2023-10-09" @default.
- W4280538049 title "In Vitro Alpha-Amylase Enzyme Assay of Hydroalcoholic Polyherbal Extract: Proof of Concept for the Development of Polyherbal Teabag Formulation for the Treatment of Diabetes" @default.
- W4280538049 cites W1536473883 @default.
- W4280538049 cites W1957284966 @default.
- W4280538049 cites W1967918346 @default.
- W4280538049 cites W2014067193 @default.
- W4280538049 cites W2040267509 @default.
- W4280538049 cites W2088674505 @default.
- W4280538049 cites W2098070958 @default.
- W4280538049 cites W2103828712 @default.
- W4280538049 cites W2140415161 @default.
- W4280538049 cites W2141769080 @default.
- W4280538049 cites W2186410522 @default.
- W4280538049 cites W2237756326 @default.
- W4280538049 cites W2312567112 @default.
- W4280538049 cites W2316639146 @default.
- W4280538049 cites W2408041907 @default.
- W4280538049 cites W2492009434 @default.
- W4280538049 cites W2500484056 @default.
- W4280538049 cites W2584810457 @default.
- W4280538049 cites W2595181394 @default.
- W4280538049 cites W2767779979 @default.
- W4280538049 cites W2884104807 @default.
- W4280538049 cites W2904928870 @default.
- W4280538049 cites W2911575024 @default.
- W4280538049 cites W2953824205 @default.
- W4280538049 cites W2966343995 @default.
- W4280538049 cites W3015091012 @default.
- W4280538049 cites W3016777921 @default.
- W4280538049 cites W3025785052 @default.
- W4280538049 cites W3027228426 @default.
- W4280538049 cites W3035860986 @default.
- W4280538049 cites W3037395110 @default.
- W4280538049 cites W3072840641 @default.
- W4280538049 cites W3086000585 @default.
- W4280538049 cites W3092167072 @default.
- W4280538049 cites W3092548783 @default.
- W4280538049 cites W3097563363 @default.
- W4280538049 cites W3138244110 @default.
- W4280538049 cites W3158401447 @default.
- W4280538049 cites W3210217353 @default.
- W4280538049 cites W3215552247 @default.
- W4280538049 cites W4200488867 @default.
- W4280538049 cites W4205718468 @default.
- W4280538049 cites W4220726416 @default.
- W4280538049 cites W4221026502 @default.
- W4280538049 cites W4223430321 @default.
- W4280538049 cites W4224004439 @default.
- W4280538049 cites W4239053538 @default.
- W4280538049 cites W4252015923 @default.
- W4280538049 doi "https://doi.org/10.1155/2022/1577957" @default.
- W4280538049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35600963" @default.
- W4280538049 hasPublicationYear "2022" @default.
- W4280538049 type Work @default.
- W4280538049 citedByCount "10" @default.
- W4280538049 countsByYear W42805380492022 @default.
- W4280538049 countsByYear W42805380492023 @default.
- W4280538049 crossrefType "journal-article" @default.
- W4280538049 hasAuthorship W4280538049A5016975298 @default.
- W4280538049 hasAuthorship W4280538049A5024563169 @default.
- W4280538049 hasAuthorship W4280538049A5044436618 @default.
- W4280538049 hasAuthorship W4280538049A5064102297 @default.
- W4280538049 hasAuthorship W4280538049A5064830000 @default.
- W4280538049 hasAuthorship W4280538049A5073155778 @default.
- W4280538049 hasAuthorship W4280538049A5079255688 @default.
- W4280538049 hasBestOaLocation W42805380491 @default.
- W4280538049 hasConcept C134018914 @default.
- W4280538049 hasConcept C142724271 @default.
- W4280538049 hasConcept C144027150 @default.
- W4280538049 hasConcept C150903083 @default.
- W4280538049 hasConcept C170835558 @default.
- W4280538049 hasConcept C173959671 @default.
- W4280538049 hasConcept C181199279 @default.
- W4280538049 hasConcept C185592680 @default.
- W4280538049 hasConcept C194671627 @default.
- W4280538049 hasConcept C195475562 @default.
- W4280538049 hasConcept C202751555 @default.
- W4280538049 hasConcept C204787440 @default.
- W4280538049 hasConcept C206103511 @default.
- W4280538049 hasConcept C207001950 @default.
- W4280538049 hasConcept C2776617576 @default.
- W4280538049 hasConcept C2777832050 @default.
- W4280538049 hasConcept C2778004101 @default.
- W4280538049 hasConcept C2778199505 @default.
- W4280538049 hasConcept C2778284287 @default.
- W4280538049 hasConcept C2779158651 @default.
- W4280538049 hasConcept C2779969877 @default.
- W4280538049 hasConcept C55493867 @default.