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• W4280542658 abstract "BackgroundOutcomes of patients with hypertrophic cardiomyopathy (HCM) following transcatheter aortic valve replacement (TAVR) remain largely unknown. This study sought to assess the clinical characteristics and outcomes of HCM patients following TAVR.MethodsWe queried the National Inpatient Sample from 2014 to 2018 for TAVR hospitalizations with and without HCM, creating a propensity-matched (PSM) cohort to compare outcomes.Results207,880 patients that underwent TAVR during the study period, 810 (0.38%) had coexisting HCM. In the unmatched population, TAVR patients with HCM compared to those without HCM, were more likely to be females, had a higher prevalence of heart failure, obesity, cancer, and history of pacemaker/implantable cardioverter defibrillation, and were more likely to have non-elective and weekend admissions (P for all <0.05). TAVR patients without HCM had higher prevalence of coronary artery disease, prior percutaneous coronary intervention, prior coronary artery bypass grafting, and peripheral arterial disease compared to their counterparts (P for all <0.05).In the propensity matched cohort, TAVR patients with HCM had significantly higher incidence of in-hospital mortality, acute kidney injury/hemodialysis, bleeding complications, vascular complications, permanent pacemaker requirement, aortic dissection, cardiogenic shock, and mechanical ventilation requirement (Table 1).ConclusionsDisclosuresR. Vyas Nothing to disclose. S. Nazir Nothing to disclose. K. Ahuja Nothing to disclose. A. M. Minhas Nothing to disclose. A. M. Elzanaty Nothing to disclose. T. Mir Nothing to disclose. M. Sheikh Nothing to disclose. BackgroundOutcomes of patients with hypertrophic cardiomyopathy (HCM) following transcatheter aortic valve replacement (TAVR) remain largely unknown. This study sought to assess the clinical characteristics and outcomes of HCM patients following TAVR. Outcomes of patients with hypertrophic cardiomyopathy (HCM) following transcatheter aortic valve replacement (TAVR) remain largely unknown. This study sought to assess the clinical characteristics and outcomes of HCM patients following TAVR. MethodsWe queried the National Inpatient Sample from 2014 to 2018 for TAVR hospitalizations with and without HCM, creating a propensity-matched (PSM) cohort to compare outcomes. We queried the National Inpatient Sample from 2014 to 2018 for TAVR hospitalizations with and without HCM, creating a propensity-matched (PSM) cohort to compare outcomes. Results207,880 patients that underwent TAVR during the study period, 810 (0.38%) had coexisting HCM. In the unmatched population, TAVR patients with HCM compared to those without HCM, were more likely to be females, had a higher prevalence of heart failure, obesity, cancer, and history of pacemaker/implantable cardioverter defibrillation, and were more likely to have non-elective and weekend admissions (P for all <0.05). TAVR patients without HCM had higher prevalence of coronary artery disease, prior percutaneous coronary intervention, prior coronary artery bypass grafting, and peripheral arterial disease compared to their counterparts (P for all <0.05).In the propensity matched cohort, TAVR patients with HCM had significantly higher incidence of in-hospital mortality, acute kidney injury/hemodialysis, bleeding complications, vascular complications, permanent pacemaker requirement, aortic dissection, cardiogenic shock, and mechanical ventilation requirement (Table 1). 207,880 patients that underwent TAVR during the study period, 810 (0.38%) had coexisting HCM. In the unmatched population, TAVR patients with HCM compared to those without HCM, were more likely to be females, had a higher prevalence of heart failure, obesity, cancer, and history of pacemaker/implantable cardioverter defibrillation, and were more likely to have non-elective and weekend admissions (P for all <0.05). TAVR patients without HCM had higher prevalence of coronary artery disease, prior percutaneous coronary intervention, prior coronary artery bypass grafting, and peripheral arterial disease compared to their counterparts (P for all <0.05). In the propensity matched cohort, TAVR patients with HCM had significantly higher incidence of in-hospital mortality, acute kidney injury/hemodialysis, bleeding complications, vascular complications, permanent pacemaker requirement, aortic dissection, cardiogenic shock, and mechanical ventilation requirement (Table 1). Conclusions DisclosuresR. Vyas Nothing to disclose. S. Nazir Nothing to disclose. K. Ahuja Nothing to disclose. A. M. Minhas Nothing to disclose. A. M. Elzanaty Nothing to disclose. T. Mir Nothing to disclose. M. Sheikh Nothing to disclose. R. Vyas Nothing to disclose. S. Nazir Nothing to disclose. K. Ahuja Nothing to disclose. A. M. Minhas Nothing to disclose. A. M. Elzanaty Nothing to disclose. T. Mir Nothing to disclose. M. Sheikh Nothing to disclose." @default.
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• W4280542658 date "2022-05-01" @default.
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• W4280542658 title "C-54 | Endovascular Transcatheter Aortic Valve Replacement Outcomes in Hypertrophic Cardiomyopathy: Insights from the National Inpatient Sample (2014-2018)" @default.
• W4280542658 doi "https://doi.org/10.1016/j.jscai.2022.100206" @default.
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