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- W4280551406 abstract "Abstract Addressing the prevalence of tick-borne disease requires robust chemical options as an integral component of Integrative Vector Management (IVM) program. Spatial repellency is a novel concept in tick bite prevention. To date, there is no standard for the evaluation of spatial repellency against ticks, despite the speculated value of volatilized chemicals in control systems. This study reports a novel vertical climb assay that was specifically created for the quantitative evaluation of spatial repellency in ticks. Controlled release devices (CRDs) were used to control the dispersion of multiple Active Ingredients (AIs) transfluthrin, metofluthrin, nootkatone, and DEET against adult females of three medically important tick species: Dermacentor variabilis, Amblyomma americanum , and Ixodes scapulari s. Results of our study indicate significant associations between AI exposure and changing in tick climbing behavior when compared controls in the absence of the AI, from several perspectives, including changes in tick movement velocity, displacement, detachment, and rate of successful vertical climbing. Metofluthrin and transfluthrin caused strong reductions in host seeking activities against D. variabilis and A. americanum , while both demonstrated slightly weaker effects against I. scapularis . Further work is planned to evaluate spatial repellency in ticks in more natural environments and assess their potential in future tick control programs." @default.
- W4280551406 created "2022-05-22" @default.
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- W4280551406 date "2022-05-17" @default.
- W4280551406 modified "2023-10-16" @default.
- W4280551406 title "A new paradigm for personal protection against ticks: efficacy of spatial repellents to reduce host seeking activities in three major tick species of medical importance" @default.
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- W4280551406 doi "https://doi.org/10.1101/2022.05.17.492268" @default.
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