FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280565532> ?p ?o ?g. }

• W4280565532 abstract "Abstract Diapause is one of the most important traits that have sustained insects to thrive. Insects can prospectively arrest their development and increase environmental stress-resistance by entering diapause. The photoperiod is the signal that indicates insects the proper timing to enter diapause. Circadian clock genes are shown to be involved in photoperiodic diapause induction in various insect species. The silkworm, Bombyx mori , enters diapause at the embryonic stage. In bivoltine strains, diapause determination is affected by embryonic temperature and photoperiodic conditions during embryonic and larval stages. Two independent studies showed that knocking out the core clock gene, period , perturb photoperiodic diapause induction. However, whether the circadian clock as whole or individual clock genes are responsible for the photoperiodic diapause induction remains unknown. In this study, using CRISPR/Cas9 we knocked out negative ( period and timeless ) and positive elements ( Clock and cycle ) in p50T, a bivoltine strain which exhibits photoperiodic diapause induction during both embryonic and larval stages. The temporal expression patterns of clock genes changed in each core clock gene knockout strain, suggesting disruption of normal feedback loops produced by circadian clock genes. Furthermore, photoperiodic diapause induction during both embryonic and larval stages was lost in all knockout strains. Our results indicate the involvement of circadian clock in photoperiodic diapause induction in B. mori . Highlights We established knockout Bombyx mori strains of four core clock genes The temporal expression patterns of clock genes changed in knockout strains Photoperiodic diapause induction was not observed in any knockout strains Graphical abstract" @default.
• W4280565532 created "2022-05-22" @default.
• W4280565532 creator A5007789584 @default.
• W4280565532 creator A5062020149 @default.
• W4280565532 date "2022-05-16" @default.
• W4280565532 modified "2023-10-15" @default.
• W4280565532 title "Knockouts of positive and negative elements of the circadian clock disrupt photoperiodic diapause induction in the silkworm, <i>Bombyx mori</i>" @default.
• W4280565532 cites W1481999684 @default.
• W4280565532 cites W1504564486 @default.
• W4280565532 cites W1825981987 @default.
• W4280565532 cites W1892228382 @default.
• W4280565532 cites W1968755313 @default.
• W4280565532 cites W1970549334 @default.
• W4280565532 cites W1978811776 @default.
• W4280565532 cites W1990354445 @default.
• W4280565532 cites W1995023912 @default.
• W4280565532 cites W2007743240 @default.
• W4280565532 cites W2009815448 @default.
• W4280565532 cites W2022987439 @default.
• W4280565532 cites W2025885587 @default.
• W4280565532 cites W2037118780 @default.
• W4280565532 cites W2047514674 @default.
• W4280565532 cites W2059186228 @default.
• W4280565532 cites W2063825124 @default.
• W4280565532 cites W2065793682 @default.
• W4280565532 cites W2068349936 @default.
• W4280565532 cites W2071738414 @default.
• W4280565532 cites W2081266461 @default.
• W4280565532 cites W2086960330 @default.
• W4280565532 cites W2092882299 @default.
• W4280565532 cites W2092934538 @default.
• W4280565532 cites W2095514153 @default.
• W4280565532 cites W2107320846 @default.
• W4280565532 cites W2114427883 @default.
• W4280565532 cites W2115839035 @default.
• W4280565532 cites W2123634741 @default.
• W4280565532 cites W2136127196 @default.
• W4280565532 cites W2138665253 @default.
• W4280565532 cites W2145782793 @default.
• W4280565532 cites W2146656260 @default.
• W4280565532 cites W2146991617 @default.
• W4280565532 cites W2147739177 @default.
• W4280565532 cites W2151305846 @default.
• W4280565532 cites W2154076545 @default.
• W4280565532 cites W2157490739 @default.
• W4280565532 cites W2161858704 @default.
• W4280565532 cites W2168288068 @default.
• W4280565532 cites W2243540852 @default.
• W4280565532 cites W2516006289 @default.
• W4280565532 cites W26113315 @default.
• W4280565532 cites W2886401172 @default.
• W4280565532 cites W2916114485 @default.
• W4280565532 cites W2926099279 @default.
• W4280565532 cites W2951214599 @default.
• W4280565532 cites W2991515832 @default.
• W4280565532 cites W3030251826 @default.
• W4280565532 cites W3080500186 @default.
• W4280565532 cites W3114618450 @default.
• W4280565532 cites W3180314031 @default.
• W4280565532 cites W3198449435 @default.
• W4280565532 cites W4235561975 @default.
• W4280565532 cites W61547824 @default.
• W4280565532 doi "https://doi.org/10.1101/2022.05.16.492110" @default.
• W4280565532 hasPublicationYear "2022" @default.
• W4280565532 type Work @default.
• W4280565532 citedByCount "0" @default.
• W4280565532 crossrefType "posted-content" @default.
• W4280565532 hasAuthorship W4280565532A5007789584 @default.
• W4280565532 hasAuthorship W4280565532A5062020149 @default.
• W4280565532 hasBestOaLocation W42805655321 @default.
• W4280565532 hasConcept C104317684 @default.
• W4280565532 hasConcept C121332964 @default.
• W4280565532 hasConcept C121446783 @default.
• W4280565532 hasConcept C133805834 @default.
• W4280565532 hasConcept C134018914 @default.
• W4280565532 hasConcept C144543706 @default.
• W4280565532 hasConcept C173758957 @default.
• W4280565532 hasConcept C182704531 @default.
• W4280565532 hasConcept C184738001 @default.
• W4280565532 hasConcept C24890656 @default.
• W4280565532 hasConcept C2778332815 @default.
• W4280565532 hasConcept C2778487026 @default.
• W4280565532 hasConcept C2781291010 @default.
• W4280565532 hasConcept C38606739 @default.
• W4280565532 hasConcept C54355233 @default.
• W4280565532 hasConcept C55969652 @default.
• W4280565532 hasConcept C59822182 @default.
• W4280565532 hasConcept C86670359 @default.
• W4280565532 hasConcept C86803240 @default.
• W4280565532 hasConcept C95444343 @default.
• W4280565532 hasConceptScore W4280565532C104317684 @default.
• W4280565532 hasConceptScore W4280565532C121332964 @default.
• W4280565532 hasConceptScore W4280565532C121446783 @default.
• W4280565532 hasConceptScore W4280565532C133805834 @default.
• W4280565532 hasConceptScore W4280565532C134018914 @default.
• W4280565532 hasConceptScore W4280565532C144543706 @default.
• W4280565532 hasConceptScore W4280565532C173758957 @default.
• W4280565532 hasConceptScore W4280565532C182704531 @default.
• W4280565532 hasConceptScore W4280565532C184738001 @default.
• W4280565532 hasConceptScore W4280565532C24890656 @default.

• next