FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280581579> ?p ?o ?g. }

• W4280581579 endingPage "401" @default.
• W4280581579 startingPage "395" @default.
• W4280581579 abstract "The development of hepatocarcinogenesis after a sustained virological response (SVR) remains an important issue affecting the balance between treatment and occupational life of workers with chronic hepatitis C virus (HCV) infection in Japan. Here, we aimed to evaluate the hepatocellular carcinoma (HCC) reducing effect and risk factors for developing HCC after SVR in patients treated with direct-acting antiviral agents (DAAs) among the working population.We studied 2579 working patients with chronic HCV infection who achieved SVR after antiviral treatment. We compared the difference in the cumulative incidence of post-SVR HCC between the interferon (IFN)-based n = 1615 and DAA (n = 964) groups. The risk factors for post-SVR HCC development were determined in the DAA group.After propensity score matching (n = 644 in each group), the HCC development rates were not significantly different between the groups (P = 0.186). Multivariate Cox regression and the cutoff values determined by the receiver operating characteristic curve analyses revealed that age ≥61 years, diabetes, lower serum albumin levels <4.0 g/dL at 24 weeks after the end of treatment (EOT), and higher serum α-fetoprotein levels ≥4.1 ng/mL at 24 weeks after the EOT were associated with the development of HCC.The HCC suppressing effect after SVR through DAA treatment is equivalent to that of IFN treatment in patients in the working population. Intensive follow-up is required after SVR with DAA treatment in Japanese workers with these risk factors to ensure the promotion of health and employment support." @default.
• W4280581579 created "2022-05-22" @default.
• W4280581579 creator A5001674051 @default.
• W4280581579 creator A5004646439 @default.
• W4280581579 creator A5014582936 @default.
• W4280581579 creator A5023392452 @default.
• W4280581579 creator A5043496840 @default.
• W4280581579 creator A5043501912 @default.
• W4280581579 creator A5044782515 @default.
• W4280581579 creator A5047212753 @default.
• W4280581579 creator A5061405035 @default.
• W4280581579 creator A5071291796 @default.
• W4280581579 creator A5088118861 @default.
• W4280581579 date "2022-05-18" @default.
• W4280581579 modified "2023-09-27" @default.
• W4280581579 title "Incidence and risk factors of hepatocellular carcinoma in patients with hepatitis C who achieved a sustained virological response through direct‐acting antiviral agents among the working population in Japan" @default.
• W4280581579 cites W1490922209 @default.
• W4280581579 cites W1760890369 @default.
• W4280581579 cites W1966804887 @default.
• W4280581579 cites W1969898114 @default.
• W4280581579 cites W2012002512 @default.
• W4280581579 cites W2022040029 @default.
• W4280581579 cites W2026778931 @default.
• W4280581579 cites W2049003089 @default.
• W4280581579 cites W2154189955 @default.
• W4280581579 cites W2162078710 @default.
• W4280581579 cites W2291726879 @default.
• W4280581579 cites W2417045008 @default.
• W4280581579 cites W2536609598 @default.
• W4280581579 cites W2556470174 @default.
• W4280581579 cites W2909402739 @default.
• W4280581579 cites W2922250370 @default.
• W4280581579 cites W2963303825 @default.
• W4280581579 cites W3000074215 @default.
• W4280581579 cites W3017997372 @default.
• W4280581579 cites W3041833990 @default.
• W4280581579 cites W3105077308 @default.
• W4280581579 cites W3107386594 @default.
• W4280581579 cites W3199798640 @default.
• W4280581579 doi "https://doi.org/10.1002/jgh3.12745" @default.
• W4280581579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35774345" @default.
• W4280581579 hasPublicationYear "2022" @default.
• W4280581579 type Work @default.
• W4280581579 citedByCount "0" @default.
• W4280581579 crossrefType "journal-article" @default.
• W4280581579 hasAuthorship W4280581579A5001674051 @default.
• W4280581579 hasAuthorship W4280581579A5004646439 @default.
• W4280581579 hasAuthorship W4280581579A5014582936 @default.
• W4280581579 hasAuthorship W4280581579A5023392452 @default.
• W4280581579 hasAuthorship W4280581579A5043496840 @default.
• W4280581579 hasAuthorship W4280581579A5043501912 @default.
• W4280581579 hasAuthorship W4280581579A5044782515 @default.
• W4280581579 hasAuthorship W4280581579A5047212753 @default.
• W4280581579 hasAuthorship W4280581579A5061405035 @default.
• W4280581579 hasAuthorship W4280581579A5071291796 @default.
• W4280581579 hasAuthorship W4280581579A5088118861 @default.
• W4280581579 hasBestOaLocation W42805815791 @default.
• W4280581579 hasConcept C120665830 @default.
• W4280581579 hasConcept C121332964 @default.
• W4280581579 hasConcept C126322002 @default.
• W4280581579 hasConcept C143998085 @default.
• W4280581579 hasConcept C203014093 @default.
• W4280581579 hasConcept C2522874641 @default.
• W4280581579 hasConcept C2776408679 @default.
• W4280581579 hasConcept C2776455275 @default.
• W4280581579 hasConcept C2778019345 @default.
• W4280581579 hasConcept C2780593183 @default.
• W4280581579 hasConcept C2908647359 @default.
• W4280581579 hasConcept C61511704 @default.
• W4280581579 hasConcept C71924100 @default.
• W4280581579 hasConcept C90924648 @default.
• W4280581579 hasConcept C99454951 @default.
• W4280581579 hasConceptScore W4280581579C120665830 @default.
• W4280581579 hasConceptScore W4280581579C121332964 @default.
• W4280581579 hasConceptScore W4280581579C126322002 @default.
• W4280581579 hasConceptScore W4280581579C143998085 @default.
• W4280581579 hasConceptScore W4280581579C203014093 @default.
• W4280581579 hasConceptScore W4280581579C2522874641 @default.
• W4280581579 hasConceptScore W4280581579C2776408679 @default.
• W4280581579 hasConceptScore W4280581579C2776455275 @default.
• W4280581579 hasConceptScore W4280581579C2778019345 @default.
• W4280581579 hasConceptScore W4280581579C2780593183 @default.
• W4280581579 hasConceptScore W4280581579C2908647359 @default.
• W4280581579 hasConceptScore W4280581579C61511704 @default.
• W4280581579 hasConceptScore W4280581579C71924100 @default.
• W4280581579 hasConceptScore W4280581579C90924648 @default.
• W4280581579 hasConceptScore W4280581579C99454951 @default.
• W4280581579 hasIssue "6" @default.
• W4280581579 hasLocation W42805815791 @default.
• W4280581579 hasLocation W42805815792 @default.
• W4280581579 hasLocation W42805815793 @default.
• W4280581579 hasLocation W42805815794 @default.
• W4280581579 hasOpenAccess W4280581579 @default.
• W4280581579 hasPrimaryLocation W42805815791 @default.
• W4280581579 hasRelatedWork W1841796848 @default.
• W4280581579 hasRelatedWork W1999271042 @default.
• W4280581579 hasRelatedWork W2008626862 @default.
• W4280581579 hasRelatedWork W2055402791 @default.

• next