FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280641626> ?p ?o ?g. }

• W4280641626 endingPage "144" @default.
• W4280641626 startingPage "133" @default.
• W4280641626 abstract "The role of the 8th American Joint Committee on Cancer (AJCC) pathological prognostic staging (PPS) on treatment-decision making of breast cancer (BC) remains unclear. This study aimed to investigate the predictive effect of the 8th AJCC PPS on the benefit of postmastectomy radiotherapy (PMRT) in N2/N3 BC.We included women with stage N2/3 BC diagnosed between 2010 and 2018 from the Surveillance, Epidemiology, and End Results database. The effect of PMRT on breast cancer-specific survival (BCSS) was evaluated using the multivariate Cox proportional-hazards models.A total of 13,445 patients were identified, including 10,547 (78.4%) patients treated with PMRT. All patients had reassigned stages based on the 8th AJCC PPS. There were 7102 patients (52.8%) that had stage changed, including 1160 patients (8.6%) were upstaged and 5942 patients (44.2%) were downstaged from the 7th AJCC anatomical staging (AS) to the 8th AJCC PPS. Regarding the 7th AJCC AS, 7603 (56.5%), 948 (7.1%), and 4895 (36.4%) were stage IIIA, IIIB, and IIIC diseases, respectively. Using the 8th AJCC PPS, 3525 (26.2%), 460 (3.4%), 1335 (9.9%), 3457 (25.7%), 2169 (19.1%), and 2100 (15.6%) patients were restaged as IB, IIA, IIB, IIIA, IIIB, and IIIC diseases, respectively. The PPS displayed increased prognostic accuracy and improved model fit with respect to BCSS compared to the 7th AS (C-index, 0.731 vs 0.605, P < 0.001; Akaike Information Criterion, 42141 vs 43118). Regarding the AS, the receipt of PMRT was associated with a better BCSS in those with stage IIIA (P = 0.004), IIIB (P = 0.003), and IIIC (P < 0.001) diseases. Using the PPS, the receipt of PMRT was not associated with a better BCSS among patients with stage IB (P = 0.446), IIA (P = 0.140), and IIB (P = 0.248) disease, while the receipt of PMRT was associated with a better BCSS for those with stage IIIA (P = 0.009), IIIB (P < 0.001), and IIIC (P < 0.001) disease.The 8th AJCC staging provides superior risk stratification and a better tool to predict the benefit of PMRT in N2/3 BC." @default.
• W4280641626 created "2022-05-22" @default.
• W4280641626 creator A5009153341 @default.
• W4280641626 creator A5033675801 @default.
• W4280641626 creator A5049262967 @default.
• W4280641626 creator A5071024580 @default.
• W4280641626 creator A5072044103 @default.
• W4280641626 date "2022-05-01" @default.
• W4280641626 modified "2023-09-26" @default.
• W4280641626 title "The Predictive Effect of the 8th AJCC Pathological Prognostic Staging on the Benefit of Postmastectomy Radiotherapy in N2/N3 Breast Cancer" @default.
• W4280641626 cites W1603035123 @default.
• W4280641626 cites W1978125585 @default.
• W4280641626 cites W2016330947 @default.
• W4280641626 cites W2103923235 @default.
• W4280641626 cites W2126446157 @default.
• W4280641626 cites W2128458647 @default.
• W4280641626 cites W2129825983 @default.
• W4280641626 cites W2140978771 @default.
• W4280641626 cites W2142457016 @default.
• W4280641626 cites W2142635246 @default.
• W4280641626 cites W2181117014 @default.
• W4280641626 cites W2209296130 @default.
• W4280641626 cites W2521999419 @default.
• W4280641626 cites W2574924994 @default.
• W4280641626 cites W2603868227 @default.
• W4280641626 cites W2767018984 @default.
• W4280641626 cites W2767892428 @default.
• W4280641626 cites W2773099418 @default.
• W4280641626 cites W2775795219 @default.
• W4280641626 cites W2797944286 @default.
• W4280641626 cites W2801231311 @default.
• W4280641626 cites W2804380739 @default.
• W4280641626 cites W2883015238 @default.
• W4280641626 cites W2889646458 @default.
• W4280641626 cites W2896848320 @default.
• W4280641626 cites W2912709508 @default.
• W4280641626 cites W2924191771 @default.
• W4280641626 cites W2932713653 @default.
• W4280641626 cites W2999417355 @default.
• W4280641626 cites W3000584661 @default.
• W4280641626 cites W3009236820 @default.
• W4280641626 cites W3011364267 @default.
• W4280641626 cites W3034106482 @default.
• W4280641626 cites W3097344029 @default.
• W4280641626 cites W3140951331 @default.
• W4280641626 cites W3193353606 @default.
• W4280641626 cites W3195966818 @default.
• W4280641626 cites W4200517423 @default.
• W4280641626 cites W4211005384 @default.
• W4280641626 cites W4211123279 @default.
• W4280641626 doi "https://doi.org/10.2147/bctt.s362355" @default.
• W4280641626 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35592354" @default.
• W4280641626 hasPublicationYear "2022" @default.
• W4280641626 type Work @default.
• W4280641626 citedByCount "1" @default.
• W4280641626 countsByYear W42806416262022 @default.
• W4280641626 crossrefType "journal-article" @default.
• W4280641626 hasAuthorship W4280641626A5009153341 @default.
• W4280641626 hasAuthorship W4280641626A5033675801 @default.
• W4280641626 hasAuthorship W4280641626A5049262967 @default.
• W4280641626 hasAuthorship W4280641626A5071024580 @default.
• W4280641626 hasAuthorship W4280641626A5072044103 @default.
• W4280641626 hasBestOaLocation W42806416261 @default.
• W4280641626 hasConcept C107130276 @default.
• W4280641626 hasConcept C121608353 @default.
• W4280641626 hasConcept C126322002 @default.
• W4280641626 hasConcept C143998085 @default.
• W4280641626 hasConcept C146357865 @default.
• W4280641626 hasConcept C151730666 @default.
• W4280641626 hasConcept C207886595 @default.
• W4280641626 hasConcept C2778527826 @default.
• W4280641626 hasConcept C2779391198 @default.
• W4280641626 hasConcept C2779660593 @default.
• W4280641626 hasConcept C29456083 @default.
• W4280641626 hasConcept C2993415550 @default.
• W4280641626 hasConcept C50382708 @default.
• W4280641626 hasConcept C509974204 @default.
• W4280641626 hasConcept C530470458 @default.
• W4280641626 hasConcept C71924100 @default.
• W4280641626 hasConcept C86803240 @default.
• W4280641626 hasConceptScore W4280641626C107130276 @default.
• W4280641626 hasConceptScore W4280641626C121608353 @default.
• W4280641626 hasConceptScore W4280641626C126322002 @default.
• W4280641626 hasConceptScore W4280641626C143998085 @default.
• W4280641626 hasConceptScore W4280641626C146357865 @default.
• W4280641626 hasConceptScore W4280641626C151730666 @default.
• W4280641626 hasConceptScore W4280641626C207886595 @default.
• W4280641626 hasConceptScore W4280641626C2778527826 @default.
• W4280641626 hasConceptScore W4280641626C2779391198 @default.
• W4280641626 hasConceptScore W4280641626C2779660593 @default.
• W4280641626 hasConceptScore W4280641626C29456083 @default.
• W4280641626 hasConceptScore W4280641626C2993415550 @default.
• W4280641626 hasConceptScore W4280641626C50382708 @default.
• W4280641626 hasConceptScore W4280641626C509974204 @default.
• W4280641626 hasConceptScore W4280641626C530470458 @default.
• W4280641626 hasConceptScore W4280641626C71924100 @default.
• W4280641626 hasConceptScore W4280641626C86803240 @default.
• W4280641626 hasLocation W42806416261 @default.

• next