Matches in SemOpenAlex for { <https://semopenalex.org/work/W4280642379> ?p ?o ?g. }
- W4280642379 endingPage "5507" @default.
- W4280642379 startingPage "5507" @default.
- W4280642379 abstract "The efficacy of skin substitutes is established for the treatment of burn injuries, but its use is not limited to this condition. This technology has the potential to improve the treatment of various conditions by offering highly advanced and personalized treatments. In vivo studies are challenging but essential to move to clinical use in humans. Mice are the most widely used species in preclinical studies, but the main drawback of this model is the limited surface area of the graft in long-term transplantation studies caused by the displacement and the contraction of the graft. We improved the conventional surgical procedures by stabilizing the chamber covering the graft with intramuscular sutures and by adding a tie-over bolster dressing. The current study was therefore performed to compare outcomes of skin grafts between the conventional and optimized skin graft model. Human self-assembled skin substitutes (SASSs) were prepared and grafted to athymic mice either by the conventional method or by the new grafting method. Graft healing and complications were assessed using digital photographs on postoperative days 7, 14, and 21. Similar structure and organization were observed by histological staining. The new grafting method reduced medium and large displacement events by 1.26-fold and medium and large contraction events by 1.8-fold, leading to a 1.6-fold increase in graft surface area compared to skin substitutes grafted with the usual method. This innovation ensures better reproducibility and consistency of skin substitute transplants on mice." @default.
- W4280642379 created "2022-05-22" @default.
- W4280642379 creator A5019256075 @default.
- W4280642379 creator A5033131271 @default.
- W4280642379 creator A5033352837 @default.
- W4280642379 creator A5053347721 @default.
- W4280642379 creator A5056145699 @default.
- W4280642379 creator A5065230255 @default.
- W4280642379 creator A5080192469 @default.
- W4280642379 creator A5091775041 @default.
- W4280642379 date "2022-05-14" @default.
- W4280642379 modified "2023-10-14" @default.
- W4280642379 title "Tie-Over Bolster Pressure Dressing Improves Outcomes of Skin Substitutes Xenografts on Athymic Mice" @default.
- W4280642379 cites W1213660979 @default.
- W4280642379 cites W1598728286 @default.
- W4280642379 cites W1791493718 @default.
- W4280642379 cites W1946268515 @default.
- W4280642379 cites W1963484569 @default.
- W4280642379 cites W1968870498 @default.
- W4280642379 cites W1969188337 @default.
- W4280642379 cites W1969722682 @default.
- W4280642379 cites W1970206229 @default.
- W4280642379 cites W1976555930 @default.
- W4280642379 cites W1976732802 @default.
- W4280642379 cites W1983030187 @default.
- W4280642379 cites W1990875443 @default.
- W4280642379 cites W1991479248 @default.
- W4280642379 cites W1993159495 @default.
- W4280642379 cites W1994290424 @default.
- W4280642379 cites W2011862370 @default.
- W4280642379 cites W2025742313 @default.
- W4280642379 cites W2029154524 @default.
- W4280642379 cites W2029497643 @default.
- W4280642379 cites W2032554052 @default.
- W4280642379 cites W2032679708 @default.
- W4280642379 cites W2034604550 @default.
- W4280642379 cites W2036097231 @default.
- W4280642379 cites W2036445618 @default.
- W4280642379 cites W2044687169 @default.
- W4280642379 cites W2051498845 @default.
- W4280642379 cites W2052724055 @default.
- W4280642379 cites W2053795936 @default.
- W4280642379 cites W2055524515 @default.
- W4280642379 cites W2065843100 @default.
- W4280642379 cites W2072369387 @default.
- W4280642379 cites W2074121444 @default.
- W4280642379 cites W2077446787 @default.
- W4280642379 cites W2079028650 @default.
- W4280642379 cites W2083644239 @default.
- W4280642379 cites W2085512015 @default.
- W4280642379 cites W2087759495 @default.
- W4280642379 cites W2098335153 @default.
- W4280642379 cites W2099424615 @default.
- W4280642379 cites W2107782876 @default.
- W4280642379 cites W2109963121 @default.
- W4280642379 cites W2122335200 @default.
- W4280642379 cites W2134801560 @default.
- W4280642379 cites W2135922435 @default.
- W4280642379 cites W2136264312 @default.
- W4280642379 cites W2140496117 @default.
- W4280642379 cites W2156782167 @default.
- W4280642379 cites W2160787125 @default.
- W4280642379 cites W2162140499 @default.
- W4280642379 cites W2163981842 @default.
- W4280642379 cites W2194592358 @default.
- W4280642379 cites W2334256277 @default.
- W4280642379 cites W2400736620 @default.
- W4280642379 cites W2413763249 @default.
- W4280642379 cites W2540334618 @default.
- W4280642379 cites W2560952256 @default.
- W4280642379 cites W2562307513 @default.
- W4280642379 cites W2591278555 @default.
- W4280642379 cites W2602547279 @default.
- W4280642379 cites W2602676411 @default.
- W4280642379 cites W2605720641 @default.
- W4280642379 cites W2619488398 @default.
- W4280642379 cites W2706195878 @default.
- W4280642379 cites W2760173530 @default.
- W4280642379 cites W2780153520 @default.
- W4280642379 cites W2809371277 @default.
- W4280642379 cites W2891442361 @default.
- W4280642379 cites W2898378414 @default.
- W4280642379 cites W2914857359 @default.
- W4280642379 cites W2975440314 @default.
- W4280642379 cites W2990724791 @default.
- W4280642379 cites W3016306795 @default.
- W4280642379 cites W3039129550 @default.
- W4280642379 cites W3112078483 @default.
- W4280642379 cites W4252601044 @default.
- W4280642379 cites W1976044017 @default.
- W4280642379 doi "https://doi.org/10.3390/ijms23105507" @default.
- W4280642379 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35628318" @default.
- W4280642379 hasPublicationYear "2022" @default.
- W4280642379 type Work @default.
- W4280642379 citedByCount "1" @default.
- W4280642379 countsByYear W42806423792023 @default.
- W4280642379 crossrefType "journal-article" @default.
- W4280642379 hasAuthorship W4280642379A5019256075 @default.