Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281252147> ?p ?o ?g. }
- W4281252147 abstract "It is reported herein that by exploiting the commonly shared bicyclic decahydroquinoline motif, a gold-catalyzed enamide-alkyne cycloisomerization reaction is developed to access tricyclic cores in a simple way. These tricyclic cores further serve as an advanced platform for the divergent enantioselective collective total syntheses of five Lycopodium alkaloids, belonging to three different structural types, in a concise and protecting-group-free fashion. The key transformations in the second phase include: 1) a transannular reductive Heck cyclization for installation of the azepane ring in fawcettidine, fawcettimine, and lycoposerramine Q; 2) a domino Mukaiyama hydration/Grob fragmentation process for construction of the ten-membered lactam system in phlegmariurine B; 3) a Fukuyama one-pot protocol for the construction of the 2-pyridone motif in lycoposerramine R. The newly developed strategy is expected to pave the way for the synthesis of other structurally related Lycopodium alkaloids." @default.
- W4281252147 created "2022-05-23" @default.
- W4281252147 creator A5008674656 @default.
- W4281252147 creator A5033500275 @default.
- W4281252147 creator A5050391884 @default.
- W4281252147 creator A5051656274 @default.
- W4281252147 creator A5054594638 @default.
- W4281252147 creator A5055576965 @default.
- W4281252147 creator A5065454870 @default.
- W4281252147 creator A5085174170 @default.
- W4281252147 date "2022-06-21" @default.
- W4281252147 modified "2023-09-27" @default.
- W4281252147 title "Collective Total Syntheses of Five <i>Lycopodium</i> Alkaloids" @default.
- W4281252147 cites W1536090444 @default.
- W4281252147 cites W1966414555 @default.
- W4281252147 cites W1966878394 @default.
- W4281252147 cites W1990015043 @default.
- W4281252147 cites W1991096030 @default.
- W4281252147 cites W1992593965 @default.
- W4281252147 cites W2003484816 @default.
- W4281252147 cites W2033076450 @default.
- W4281252147 cites W2035118524 @default.
- W4281252147 cites W2043799133 @default.
- W4281252147 cites W2047177391 @default.
- W4281252147 cites W2049069355 @default.
- W4281252147 cites W2053375662 @default.
- W4281252147 cites W2058715195 @default.
- W4281252147 cites W2059838799 @default.
- W4281252147 cites W2060741019 @default.
- W4281252147 cites W2068067410 @default.
- W4281252147 cites W2073550498 @default.
- W4281252147 cites W2075384695 @default.
- W4281252147 cites W2077439800 @default.
- W4281252147 cites W2083712247 @default.
- W4281252147 cites W2127031980 @default.
- W4281252147 cites W2132214379 @default.
- W4281252147 cites W2135857641 @default.
- W4281252147 cites W2136022643 @default.
- W4281252147 cites W2136051187 @default.
- W4281252147 cites W2142981107 @default.
- W4281252147 cites W2148841403 @default.
- W4281252147 cites W2154497450 @default.
- W4281252147 cites W2156597295 @default.
- W4281252147 cites W2160669697 @default.
- W4281252147 cites W2160687522 @default.
- W4281252147 cites W2162879534 @default.
- W4281252147 cites W2170792068 @default.
- W4281252147 cites W2258142940 @default.
- W4281252147 cites W2313409884 @default.
- W4281252147 cites W2326884310 @default.
- W4281252147 cites W2333723080 @default.
- W4281252147 cites W2340610485 @default.
- W4281252147 cites W2470659897 @default.
- W4281252147 cites W2512147243 @default.
- W4281252147 cites W2515897482 @default.
- W4281252147 cites W2561716712 @default.
- W4281252147 cites W2562371084 @default.
- W4281252147 cites W2609537524 @default.
- W4281252147 cites W2615502676 @default.
- W4281252147 cites W2779626377 @default.
- W4281252147 cites W2949179667 @default.
- W4281252147 cites W2950557735 @default.
- W4281252147 cites W2951721940 @default.
- W4281252147 cites W2951765310 @default.
- W4281252147 cites W3081829108 @default.
- W4281252147 cites W3136020043 @default.
- W4281252147 cites W3173194757 @default.
- W4281252147 cites W3203286538 @default.
- W4281252147 cites W4205211565 @default.
- W4281252147 cites W4213382847 @default.
- W4281252147 cites W4243753972 @default.
- W4281252147 cites W4247444974 @default.
- W4281252147 cites W4250011335 @default.
- W4281252147 cites W4254191209 @default.
- W4281252147 cites W4255967654 @default.
- W4281252147 doi "https://doi.org/10.1002/anie.202205439" @default.
- W4281252147 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35596233" @default.
- W4281252147 hasPublicationYear "2022" @default.
- W4281252147 type Work @default.
- W4281252147 citedByCount "5" @default.
- W4281252147 countsByYear W42812521472022 @default.
- W4281252147 countsByYear W42812521472023 @default.
- W4281252147 crossrefType "journal-article" @default.
- W4281252147 hasAuthorship W4281252147A5008674656 @default.
- W4281252147 hasAuthorship W4281252147A5033500275 @default.
- W4281252147 hasAuthorship W4281252147A5050391884 @default.
- W4281252147 hasAuthorship W4281252147A5051656274 @default.
- W4281252147 hasAuthorship W4281252147A5054594638 @default.
- W4281252147 hasAuthorship W4281252147A5055576965 @default.
- W4281252147 hasAuthorship W4281252147A5065454870 @default.
- W4281252147 hasAuthorship W4281252147A5085174170 @default.
- W4281252147 hasConcept C146686406 @default.
- W4281252147 hasConcept C161790260 @default.
- W4281252147 hasConcept C178790620 @default.
- W4281252147 hasConcept C185592680 @default.
- W4281252147 hasConcept C21951064 @default.
- W4281252147 hasConcept C24961977 @default.
- W4281252147 hasConcept C2776416436 @default.
- W4281252147 hasConcept C2776788722 @default.
- W4281252147 hasConcept C2777394570 @default.