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- W4281298032 abstract "Loss of bone and muscle mass is a frequent aging condition and has become a growing public health problem. The term osteosarcopenia denotes close links between bone and muscle. Mechanical exercise was once thought to be the only mechanism of crosstalk between muscle and bone. Sclerostin is an important player in the process of unloading-induced bone loss and plays an important role in mechanotransduction in the bone. Furthermore, bones and muscles are categorized as endocrine organs because they produce hormone-like substances, resulting in bone-muscle crosstalk. Sclerostin, an inhibitor of bone development, has recently been shown to play a role in myogenesis. This review discusses the importance of sclerostin in bone-muscle crosstalk." @default.
- W4281298032 created "2022-05-24" @default.
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- W4281298032 date "2022-06-30" @default.
- W4281298032 modified "2023-09-28" @default.
- W4281298032 title "Importance of Sclerostin as Bone-Muscle Mediator Crosstalk" @default.
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- W4281298032 doi "https://doi.org/10.4235/agmr.22.0036" @default.
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