Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281386870> ?p ?o ?g. }
- W4281386870 endingPage "135022" @default.
- W4281386870 startingPage "135022" @default.
- W4281386870 abstract "Pharmaceutical residues are released in the aquatic environment due to incomplete removal from wastewater. With the presence of multiple chemicals in sewage waters, contaminants may adversely affect the effectiveness of a wastewater treatment plant (WWTP). In certain cases, discharged metabolites are transformed back into their pristine structure and become bioactive again. Other compounds are persistent and can withstand conventional wastewater treatment. When WWTP effluents are released in surface waters, pristine and persistent chemicals can affect the aquatic environment. To complement WWTPs and circumvent incomplete removal of unwanted chemicals or pharmaceuticals, on-site wastewater treatment can contribute to their removal. Advanced oxidation processes (AOPs) are very powerful techniques for the abatement of pharmaceuticals, however, under certain circumstances reactive toxic by-products can be produced. We studied the application of on-site AOPs in a laboratory setting. It is expected that treatment at the contamination source can eliminate the worst polluters. Thermal plasma and UV/H2O2 oxidation were applied on simulation matrices, Milli-Q and synthetic sewage water spiked with 10 different pharmaceuticals in a range of 0.1 up to 2400 μg/L. In addition, untreated end-of-pipe hospital effluent was also subjected to oxidative treatment. The matrices were activated for 180 min and added to cultured HeLa cells. The cells were 24 h and 48 h exposed at 37 °C and subsequently markers for oxidative stress and viability were measured. During the UV/H2O2 treatment periods no toxicity was observed. After thermal plasma activation of Milli-Q water (150 and 180 min) toxicity was observed. Direct application of thermal plasma treatment in hospital sewage water caused elimination of toxic substances. The low cytotoxicity of treated pharmaceutical residues is likely to become negligible if plasma pre-treated on-site wastewater is further diluted with other sewage water streams, before reaching the WWTP. Our study suggests that AOPs may be promising technologies to remove a substantial portion of pharmaceutical components by degradation at the source. Further studies will have to be performed to verify the feasibility of upscaling this technology from the benchtop to practice." @default.
- W4281386870 created "2022-05-25" @default.
- W4281386870 creator A5008048278 @default.
- W4281386870 creator A5008996848 @default.
- W4281386870 creator A5028519945 @default.
- W4281386870 creator A5034621061 @default.
- W4281386870 creator A5038739372 @default.
- W4281386870 creator A5039187069 @default.
- W4281386870 creator A5048155734 @default.
- W4281386870 creator A5078158475 @default.
- W4281386870 date "2022-09-01" @default.
- W4281386870 modified "2023-09-23" @default.
- W4281386870 title "Determination of cytotoxicity following oxidative treatment of pharmaceutical residues in wastewater" @default.
- W4281386870 cites W180053460 @default.
- W4281386870 cites W1862690475 @default.
- W4281386870 cites W1978474340 @default.
- W4281386870 cites W1983116264 @default.
- W4281386870 cites W1987152934 @default.
- W4281386870 cites W1995118546 @default.
- W4281386870 cites W2022811030 @default.
- W4281386870 cites W2026404822 @default.
- W4281386870 cites W2034980524 @default.
- W4281386870 cites W2036501192 @default.
- W4281386870 cites W2039109202 @default.
- W4281386870 cites W2048255582 @default.
- W4281386870 cites W2049287823 @default.
- W4281386870 cites W2056055328 @default.
- W4281386870 cites W2145819020 @default.
- W4281386870 cites W2145937475 @default.
- W4281386870 cites W2182766101 @default.
- W4281386870 cites W2312266417 @default.
- W4281386870 cites W2323580420 @default.
- W4281386870 cites W2326449022 @default.
- W4281386870 cites W2345499649 @default.
- W4281386870 cites W2398202111 @default.
- W4281386870 cites W2544753069 @default.
- W4281386870 cites W2550604964 @default.
- W4281386870 cites W2555988357 @default.
- W4281386870 cites W2597495002 @default.
- W4281386870 cites W2747212840 @default.
- W4281386870 cites W2749172718 @default.
- W4281386870 cites W2772768566 @default.
- W4281386870 cites W2791356649 @default.
- W4281386870 cites W2791713766 @default.
- W4281386870 cites W2793355316 @default.
- W4281386870 cites W2799633917 @default.
- W4281386870 cites W2808931055 @default.
- W4281386870 cites W2884362544 @default.
- W4281386870 cites W2908412131 @default.
- W4281386870 cites W2934724291 @default.
- W4281386870 cites W2951234620 @default.
- W4281386870 cites W2953283988 @default.
- W4281386870 cites W2965777707 @default.
- W4281386870 cites W2996663534 @default.
- W4281386870 cites W3014473008 @default.
- W4281386870 cites W3040024577 @default.
- W4281386870 cites W3090283221 @default.
- W4281386870 cites W3130643567 @default.
- W4281386870 cites W3195697170 @default.
- W4281386870 doi "https://doi.org/10.1016/j.chemosphere.2022.135022" @default.
- W4281386870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35618071" @default.
- W4281386870 hasPublicationYear "2022" @default.
- W4281386870 type Work @default.
- W4281386870 citedByCount "2" @default.
- W4281386870 countsByYear W42813868702022 @default.
- W4281386870 countsByYear W42813868702023 @default.
- W4281386870 crossrefType "journal-article" @default.
- W4281386870 hasAuthorship W4281386870A5008048278 @default.
- W4281386870 hasAuthorship W4281386870A5008996848 @default.
- W4281386870 hasAuthorship W4281386870A5028519945 @default.
- W4281386870 hasAuthorship W4281386870A5034621061 @default.
- W4281386870 hasAuthorship W4281386870A5038739372 @default.
- W4281386870 hasAuthorship W4281386870A5039187069 @default.
- W4281386870 hasAuthorship W4281386870A5048155734 @default.
- W4281386870 hasAuthorship W4281386870A5078158475 @default.
- W4281386870 hasBestOaLocation W42813868702 @default.
- W4281386870 hasConcept C107872376 @default.
- W4281386870 hasConcept C112570922 @default.
- W4281386870 hasConcept C127413603 @default.
- W4281386870 hasConcept C147455438 @default.
- W4281386870 hasConcept C178790620 @default.
- W4281386870 hasConcept C185592680 @default.
- W4281386870 hasConcept C18903297 @default.
- W4281386870 hasConcept C29730261 @default.
- W4281386870 hasConcept C39432304 @default.
- W4281386870 hasConcept C528095902 @default.
- W4281386870 hasConcept C548081761 @default.
- W4281386870 hasConcept C57442070 @default.
- W4281386870 hasConcept C58790150 @default.
- W4281386870 hasConcept C82685317 @default.
- W4281386870 hasConcept C8625798 @default.
- W4281386870 hasConcept C86803240 @default.
- W4281386870 hasConcept C87717796 @default.
- W4281386870 hasConcept C94061648 @default.
- W4281386870 hasConceptScore W4281386870C107872376 @default.
- W4281386870 hasConceptScore W4281386870C112570922 @default.
- W4281386870 hasConceptScore W4281386870C127413603 @default.
- W4281386870 hasConceptScore W4281386870C147455438 @default.