Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281396880> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W4281396880 endingPage "319" @default.
- W4281396880 startingPage "315" @default.
- W4281396880 abstract "In early December 2020, the antifungal medication, itraconazole (ITCZ), was mistakenly contaminated with rilmazafone in Japan. Healthcare professionals reported adverse drug reaction reports associated with ITCZ and included central nervous system-depression symptoms such as dizziness, lightheadedness, loss of consciousness, and intense drowsiness.We examined ITCZ-associated suspicious cases using the Japanese Adverse Drug Event Report (JADER) database to determine the impact of adverse drug reaction reporting on post-marketing safety measures.Adverse drug reaction reports in which the suspicious or concomitant medication was ITCZ or fluconazole (FLCZ) were extracted from the JADER dataset. The number of adverse drug reaction reports associated with central nervous system-depression adverse drug reactions were counted, and chronological changes were compared with ITCZ and FLCZ.Of the 713,893 adverse drug reaction reports in the JADER database, 5048 cases were associated with ITCZ and 6007 cases with FLCZ. When ITCZ contamination occurred, the number of adverse drug reaction reports associated with ITCZ increased rapidly, while those with FLCZ did not. In addition, the proportion of central nervous system-depression adverse drug reactions increased only in the ITCZ-associated report.An incident of ITCZ contamination with rilmazafone was detected on the JADER retrospectively. This case highlights the importance of spontaneous adverse drug reaction reporting, even if the causal relationship between the drug and adverse drug reaction is unknown." @default.
- W4281396880 created "2022-05-25" @default.
- W4281396880 creator A5001383498 @default.
- W4281396880 creator A5034834224 @default.
- W4281396880 creator A5063732330 @default.
- W4281396880 date "2022-05-23" @default.
- W4281396880 modified "2023-10-09" @default.
- W4281396880 title "Itraconazole Contaminated with Rilmazafone in Japan: A Retrospective Analysis Using the Japanese Adverse Drug Event Report Database" @default.
- W4281396880 cites W1562265147 @default.
- W4281396880 cites W2057676788 @default.
- W4281396880 cites W2732137101 @default.
- W4281396880 cites W2889572106 @default.
- W4281396880 cites W2995674745 @default.
- W4281396880 cites W3004468240 @default.
- W4281396880 cites W3026508938 @default.
- W4281396880 cites W3141665404 @default.
- W4281396880 doi "https://doi.org/10.1007/s40801-022-00306-6" @default.
- W4281396880 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35606678" @default.
- W4281396880 hasPublicationYear "2022" @default.
- W4281396880 type Work @default.
- W4281396880 citedByCount "2" @default.
- W4281396880 countsByYear W42813968802022 @default.
- W4281396880 countsByYear W42813968802023 @default.
- W4281396880 crossrefType "journal-article" @default.
- W4281396880 hasAuthorship W4281396880A5001383498 @default.
- W4281396880 hasAuthorship W4281396880A5034834224 @default.
- W4281396880 hasAuthorship W4281396880A5063732330 @default.
- W4281396880 hasBestOaLocation W42813968801 @default.
- W4281396880 hasConcept C139719470 @default.
- W4281396880 hasConcept C16005928 @default.
- W4281396880 hasConcept C162324750 @default.
- W4281396880 hasConcept C197934379 @default.
- W4281396880 hasConcept C2776867660 @default.
- W4281396880 hasConcept C2777071850 @default.
- W4281396880 hasConcept C2779548794 @default.
- W4281396880 hasConcept C2780035454 @default.
- W4281396880 hasConcept C2780542314 @default.
- W4281396880 hasConcept C71924100 @default.
- W4281396880 hasConcept C98274493 @default.
- W4281396880 hasConceptScore W4281396880C139719470 @default.
- W4281396880 hasConceptScore W4281396880C16005928 @default.
- W4281396880 hasConceptScore W4281396880C162324750 @default.
- W4281396880 hasConceptScore W4281396880C197934379 @default.
- W4281396880 hasConceptScore W4281396880C2776867660 @default.
- W4281396880 hasConceptScore W4281396880C2777071850 @default.
- W4281396880 hasConceptScore W4281396880C2779548794 @default.
- W4281396880 hasConceptScore W4281396880C2780035454 @default.
- W4281396880 hasConceptScore W4281396880C2780542314 @default.
- W4281396880 hasConceptScore W4281396880C71924100 @default.
- W4281396880 hasConceptScore W4281396880C98274493 @default.
- W4281396880 hasFunder F4320311405 @default.
- W4281396880 hasIssue "3" @default.
- W4281396880 hasLocation W42813968801 @default.
- W4281396880 hasLocation W42813968802 @default.
- W4281396880 hasLocation W42813968803 @default.
- W4281396880 hasOpenAccess W4281396880 @default.
- W4281396880 hasPrimaryLocation W42813968801 @default.
- W4281396880 hasRelatedWork W1589946262 @default.
- W4281396880 hasRelatedWork W2351435130 @default.
- W4281396880 hasRelatedWork W2368117378 @default.
- W4281396880 hasRelatedWork W2373673832 @default.
- W4281396880 hasRelatedWork W2375393165 @default.
- W4281396880 hasRelatedWork W2377211821 @default.
- W4281396880 hasRelatedWork W2736011018 @default.
- W4281396880 hasRelatedWork W2913598963 @default.
- W4281396880 hasRelatedWork W3031362645 @default.
- W4281396880 hasRelatedWork W4281396880 @default.
- W4281396880 hasVolume "9" @default.
- W4281396880 isParatext "false" @default.
- W4281396880 isRetracted "false" @default.
- W4281396880 workType "article" @default.