Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281480607> ?p ?o ?g. }
- W4281480607 endingPage "203" @default.
- W4281480607 startingPage "192" @default.
- W4281480607 abstract "Chimeric antigen receptor (CAR) T cell therapy is an effective treatment for hematological malignancies, which have experienced the development of CD19 CAR-T cells for B lymphoblastic leukemia and lymphoma, B cell maturation antigen (BCMA) CAR-T cells for multiple myeloid, and more recently, the development of CD7 CAR-T cells for T cell malignancies. There are more obstacles for myeloid malignancies compared to other hematological malignancies in this field, thus concerning researches are in more diverse ways. In order to obtain more effective clinical CAR-T cells with lower side effects, scientists have developed multi-target CAR-T cells, universal CAR-T cells, as well as CAR-T cells, CAR-NK cells, CAR-iMac cells derived from induced pluripotent stem cells (iPSC) by genetic engineering. Chinese scientists have made significant contribution to the invention and manufacture of origin CAR-T cells and the establishment of an intact clinical research system. This review introduces the latest progress involving CAR-T cell therapy for hematological malignancies including B lymphoblastic malignancies, T lymphoblastic malignancies and myeloid malignancies, and also discuss the future developments including multi-target, universal and iPSC-derived CAR-related cell therapy." @default.
- W4281480607 created "2022-05-26" @default.
- W4281480607 creator A5011150668 @default.
- W4281480607 creator A5023955459 @default.
- W4281480607 creator A5034750589 @default.
- W4281480607 creator A5057403645 @default.
- W4281480607 creator A5064376232 @default.
- W4281480607 date "2022-04-01" @default.
- W4281480607 modified "2023-09-25" @default.
- W4281480607 title "Progress on CAR-T cell therapy for hematological malignancies" @default.
- W4281480607 cites W1881216623 @default.
- W4281480607 cites W1967995010 @default.
- W4281480607 cites W1976400767 @default.
- W4281480607 cites W2028069487 @default.
- W4281480607 cites W2028460943 @default.
- W4281480607 cites W2028645361 @default.
- W4281480607 cites W2046160219 @default.
- W4281480607 cites W2047205338 @default.
- W4281480607 cites W2068173904 @default.
- W4281480607 cites W2077994554 @default.
- W4281480607 cites W2084647551 @default.
- W4281480607 cites W2084996241 @default.
- W4281480607 cites W2107806760 @default.
- W4281480607 cites W2113802879 @default.
- W4281480607 cites W2118796952 @default.
- W4281480607 cites W2138977668 @default.
- W4281480607 cites W2155781172 @default.
- W4281480607 cites W2415765055 @default.
- W4281480607 cites W2558503402 @default.
- W4281480607 cites W2560105972 @default.
- W4281480607 cites W2560739488 @default.
- W4281480607 cites W2561777634 @default.
- W4281480607 cites W2579192242 @default.
- W4281480607 cites W2593086395 @default.
- W4281480607 cites W2617763104 @default.
- W4281480607 cites W2621998980 @default.
- W4281480607 cites W2773804840 @default.
- W4281480607 cites W2775982617 @default.
- W4281480607 cites W2787301955 @default.
- W4281480607 cites W2787621143 @default.
- W4281480607 cites W2788920241 @default.
- W4281480607 cites W2802646364 @default.
- W4281480607 cites W2810715813 @default.
- W4281480607 cites W2916124977 @default.
- W4281480607 cites W2943335541 @default.
- W4281480607 cites W2965223724 @default.
- W4281480607 cites W2969348242 @default.
- W4281480607 cites W2982584762 @default.
- W4281480607 cites W2982859960 @default.
- W4281480607 cites W2984531044 @default.
- W4281480607 cites W2987673820 @default.
- W4281480607 cites W2987933200 @default.
- W4281480607 cites W2997100125 @default.
- W4281480607 cites W3021616332 @default.
- W4281480607 cites W3022543485 @default.
- W4281480607 cites W3036279197 @default.
- W4281480607 cites W3038359909 @default.
- W4281480607 cites W3043369050 @default.
- W4281480607 cites W3082855561 @default.
- W4281480607 cites W3089727781 @default.
- W4281480607 cites W3094079847 @default.
- W4281480607 cites W3106079805 @default.
- W4281480607 cites W3130050285 @default.
- W4281480607 cites W3132062361 @default.
- W4281480607 cites W3133229959 @default.
- W4281480607 cites W3142830907 @default.
- W4281480607 cites W3158872906 @default.
- W4281480607 cites W3159345813 @default.
- W4281480607 cites W3165125118 @default.
- W4281480607 cites W3173305141 @default.
- W4281480607 cites W3183792933 @default.
- W4281480607 cites W3185250096 @default.
- W4281480607 cites W3186480626 @default.
- W4281480607 cites W3201013983 @default.
- W4281480607 cites W3204328954 @default.
- W4281480607 cites W3206783250 @default.
- W4281480607 cites W3211534843 @default.
- W4281480607 cites W3212997432 @default.
- W4281480607 cites W3214115566 @default.
- W4281480607 cites W3216840960 @default.
- W4281480607 cites W4210589143 @default.
- W4281480607 cites W4226034445 @default.
- W4281480607 doi "https://doi.org/10.3724/zdxbyxb-2022-0055" @default.
- W4281480607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36161291" @default.
- W4281480607 hasPublicationYear "2022" @default.
- W4281480607 type Work @default.
- W4281480607 citedByCount "1" @default.
- W4281480607 countsByYear W42814806072023 @default.
- W4281480607 crossrefType "journal-article" @default.
- W4281480607 hasAuthorship W4281480607A5011150668 @default.
- W4281480607 hasAuthorship W4281480607A5023955459 @default.
- W4281480607 hasAuthorship W4281480607A5034750589 @default.
- W4281480607 hasAuthorship W4281480607A5057403645 @default.
- W4281480607 hasAuthorship W4281480607A5064376232 @default.
- W4281480607 hasBestOaLocation W42814806072 @default.
- W4281480607 hasConcept C104317684 @default.
- W4281480607 hasConcept C107459253 @default.
- W4281480607 hasConcept C10882517 @default.