Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281481602> ?p ?o ?g. }
- W4281481602 abstract "Abstract A novel and facile post-mortem interval (PMI) biosensor was fabricated using a double-label strategy to detect the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) biomarker. A monoclonal anti-GAPDH antibody was immobilized on a surface label containing cadmium selenide quantum dots (CdSe QDs) on a cysteamine graphene oxide (Cys-GO) self-assembled monolayer. Glucose oxidase (GOx) was used as a signal label to conjugate with GAPDH. GAPDH recognition was achieved through the dissolution of the surface-attached CdSe QDs by hydrogen peroxide generated through GAPDH-conjugated GOx-catalyzed β -glucose oxidation. To enhance sensitivity, a competitive interaction was introduced between free and conjugated GAPDH to the active site of the anti-GAPDH antibody. The electrochemical response due to CdSe dissolution decreased proportionally with the concentration of free GAPDH. Differential pulsed voltammetry was conducted to determine the analytical characteristics of the immunosensor, including the limit of detection, linear dynamic range, target selectivity, system stability, and applicability toward the analysis of real samples." @default.
- W4281481602 created "2022-05-26" @default.
- W4281481602 creator A5000794048 @default.
- W4281481602 creator A5021187140 @default.
- W4281481602 creator A5021367217 @default.
- W4281481602 creator A5054647892 @default.
- W4281481602 creator A5061526791 @default.
- W4281481602 creator A5064954990 @default.
- W4281481602 creator A5087166893 @default.
- W4281481602 date "2022-05-25" @default.
- W4281481602 modified "2023-09-25" @default.
- W4281481602 title "Novel electrochemical PMI marker biosensor based on quantum dot dissolution using a double-label strategy" @default.
- W4281481602 cites W1909628715 @default.
- W4281481602 cites W1966288401 @default.
- W4281481602 cites W1971748079 @default.
- W4281481602 cites W1975860847 @default.
- W4281481602 cites W1977882828 @default.
- W4281481602 cites W1983469218 @default.
- W4281481602 cites W2024978079 @default.
- W4281481602 cites W2031734182 @default.
- W4281481602 cites W2037318709 @default.
- W4281481602 cites W2038019957 @default.
- W4281481602 cites W2038789448 @default.
- W4281481602 cites W2043648791 @default.
- W4281481602 cites W2044348063 @default.
- W4281481602 cites W2045448020 @default.
- W4281481602 cites W2059598700 @default.
- W4281481602 cites W2071462605 @default.
- W4281481602 cites W2081839060 @default.
- W4281481602 cites W2085582511 @default.
- W4281481602 cites W2086702244 @default.
- W4281481602 cites W2086798258 @default.
- W4281481602 cites W2165495099 @default.
- W4281481602 cites W2239222407 @default.
- W4281481602 cites W2313242677 @default.
- W4281481602 cites W2320298918 @default.
- W4281481602 cites W2334035222 @default.
- W4281481602 cites W2516278450 @default.
- W4281481602 cites W2573607231 @default.
- W4281481602 cites W2616187906 @default.
- W4281481602 cites W2969948464 @default.
- W4281481602 cites W3198527505 @default.
- W4281481602 cites W3206788854 @default.
- W4281481602 cites W4200424894 @default.
- W4281481602 cites W4205165621 @default.
- W4281481602 cites W4206373033 @default.
- W4281481602 cites W4210759909 @default.
- W4281481602 cites W4212861600 @default.
- W4281481602 cites W4220935456 @default.
- W4281481602 doi "https://doi.org/10.1038/s41598-022-12444-6" @default.
- W4281481602 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35614074" @default.
- W4281481602 hasPublicationYear "2022" @default.
- W4281481602 type Work @default.
- W4281481602 citedByCount "1" @default.
- W4281481602 countsByYear W42814816022023 @default.
- W4281481602 crossrefType "journal-article" @default.
- W4281481602 hasAuthorship W4281481602A5000794048 @default.
- W4281481602 hasAuthorship W4281481602A5021187140 @default.
- W4281481602 hasAuthorship W4281481602A5021367217 @default.
- W4281481602 hasAuthorship W4281481602A5054647892 @default.
- W4281481602 hasAuthorship W4281481602A5061526791 @default.
- W4281481602 hasAuthorship W4281481602A5064954990 @default.
- W4281481602 hasAuthorship W4281481602A5087166893 @default.
- W4281481602 hasBestOaLocation W42814816021 @default.
- W4281481602 hasConcept C119128265 @default.
- W4281481602 hasConcept C124657808 @default.
- W4281481602 hasConcept C134792803 @default.
- W4281481602 hasConcept C139369640 @default.
- W4281481602 hasConcept C147789679 @default.
- W4281481602 hasConcept C160756335 @default.
- W4281481602 hasConcept C171250308 @default.
- W4281481602 hasConcept C17525397 @default.
- W4281481602 hasConcept C181199279 @default.
- W4281481602 hasConcept C185592680 @default.
- W4281481602 hasConcept C192562407 @default.
- W4281481602 hasConcept C2776317432 @default.
- W4281481602 hasConcept C2777869211 @default.
- W4281481602 hasConcept C2779525745 @default.
- W4281481602 hasConcept C43617362 @default.
- W4281481602 hasConcept C52859227 @default.
- W4281481602 hasConcept C55493867 @default.
- W4281481602 hasConceptScore W4281481602C119128265 @default.
- W4281481602 hasConceptScore W4281481602C124657808 @default.
- W4281481602 hasConceptScore W4281481602C134792803 @default.
- W4281481602 hasConceptScore W4281481602C139369640 @default.
- W4281481602 hasConceptScore W4281481602C147789679 @default.
- W4281481602 hasConceptScore W4281481602C160756335 @default.
- W4281481602 hasConceptScore W4281481602C171250308 @default.
- W4281481602 hasConceptScore W4281481602C17525397 @default.
- W4281481602 hasConceptScore W4281481602C181199279 @default.
- W4281481602 hasConceptScore W4281481602C185592680 @default.
- W4281481602 hasConceptScore W4281481602C192562407 @default.
- W4281481602 hasConceptScore W4281481602C2776317432 @default.
- W4281481602 hasConceptScore W4281481602C2777869211 @default.
- W4281481602 hasConceptScore W4281481602C2779525745 @default.
- W4281481602 hasConceptScore W4281481602C43617362 @default.
- W4281481602 hasConceptScore W4281481602C52859227 @default.
- W4281481602 hasConceptScore W4281481602C55493867 @default.
- W4281481602 hasFunder F4320321204 @default.
- W4281481602 hasFunder F4320322030 @default.