FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281486952> ?p ?o ?g. }

• W4281486952 endingPage "469" @default.
• W4281486952 startingPage "452" @default.
• W4281486952 abstract "Neoadjuvant chemotherapy (NACT) combined with surgery is regarded as an effective treatment for advanced gastric cancer (AGC). Laparoscopic surgery represents the mainstream of minimally invasive surgery. Currently, surgeons focus more on surgical safety and oncological outcomes of laparoscopic gastrectomy after NACT. Thus, we sought to evaluate short- and long-term outcomes between laparoscopic total gastrectomy (LTG) and open total gastrectomy (OTG) after NACT.To compare the short and long-term outcomes between LTG and OTG for AGC after NACT.We retrospectively collected the clinicopathological data of 136 patients who accepted gastrectomy after NACT from June 2012 to June 2019, including 61 patients who underwent LTG and 75 who underwent OTG. Clinicopathological characteristics between the LTG and OTG groups showed no significant difference. SPSS 26.0, R software, and GraphPad PRISM 8.0 were used to perform statistical analyses.Of the 136 patients included, eight acquired pathological complete response, and the objective response rate was 47.8% (65/136). The LTG group had longer operation time (P = 0.015), less blood loss (P = 0.003), shorter days to first flatus (P < 0.001), and shorter postoperative hospitalization days (P < 0.001). LTG spent more surgical cost than OTG (P < 0.001), while total hospitalized cost of LTG was less than OTG (P < 0.001). 21 (28.0%) patients in the OTG group and 14 (23.0%) in the LTG group had 30-d postoperative complications, but there was no significant difference between the two groups (P = 0.503). The 3-year overall survival (OS) rate was 60.6% and 64.6% in the LTG and OTG groups, respectively [hazard ratio (HR) = 0.859, 95% confidence interval (CI): 0.522-1.412, P = 0.546], while the 3-year disease-free survival (DFS) rate was 54.5% and 51.8% in the LTG and OTG group, respectively (HR = 0.947, 95%CI: 0.582-1.539, P = 0.823). Multivariate cox analysis showed that body mass index and pTNM stage were independent risk factors for OS while vascular invasion and pTNM stage were independent risk factors for DFS (P < 0.05).After NACT, LTG shows comparable 30-d postoperative morbidity as well as 3-year OS and DFS rate to OTG. We recommend that experienced surgeons select LTG other than OTG for proper AGC patients after NACT." @default.
• W4281486952 created "2022-05-26" @default.
• W4281486952 creator A5008659449 @default.
• W4281486952 creator A5013382392 @default.
• W4281486952 creator A5014672382 @default.
• W4281486952 creator A5014711277 @default.
• W4281486952 creator A5020727273 @default.
• W4281486952 creator A5053463786 @default.
• W4281486952 creator A5068900082 @default.
• W4281486952 creator A5072011654 @default.
• W4281486952 creator A5078143614 @default.
• W4281486952 creator A5084644971 @default.
• W4281486952 date "2022-05-27" @default.
• W4281486952 modified "2023-10-18" @default.
• W4281486952 title "Short and long-term outcomes between laparoscopic and open total gastrectomy for advanced gastric cancer after neoadjuvant chemotherapy" @default.
• W4281486952 cites W1550510598 @default.
• W4281486952 cites W185544211 @default.
• W4281486952 cites W2013554663 @default.
• W4281486952 cites W2019607817 @default.
• W4281486952 cites W2099557520 @default.
• W4281486952 cites W2115072149 @default.
• W4281486952 cites W2610372626 @default.
• W4281486952 cites W2612587561 @default.
• W4281486952 cites W2789313832 @default.
• W4281486952 cites W2893508330 @default.
• W4281486952 cites W2902168235 @default.
• W4281486952 cites W2938774982 @default.
• W4281486952 cites W2947862269 @default.
• W4281486952 cites W2954693483 @default.
• W4281486952 cites W2969272124 @default.
• W4281486952 cites W2976491173 @default.
• W4281486952 cites W2990486250 @default.
• W4281486952 cites W3009868088 @default.
• W4281486952 cites W3015462383 @default.
• W4281486952 cites W3023840002 @default.
• W4281486952 cites W3024204649 @default.
• W4281486952 cites W3033307600 @default.
• W4281486952 cites W3046380630 @default.
• W4281486952 cites W3047594669 @default.
• W4281486952 cites W3056694921 @default.
• W4281486952 cites W3101548194 @default.
• W4281486952 cites W3120903788 @default.
• W4281486952 cites W3128646645 @default.
• W4281486952 cites W3158652977 @default.
• W4281486952 cites W3173726000 @default.
• W4281486952 cites W3179103786 @default.
• W4281486952 cites W4250948394 @default.
• W4281486952 doi "https://doi.org/10.4240/wjgs.v14.i5.452" @default.
• W4281486952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35734616" @default.
• W4281486952 hasPublicationYear "2022" @default.
• W4281486952 type Work @default.
• W4281486952 citedByCount "4" @default.
• W4281486952 countsByYear W42814869522022 @default.
• W4281486952 countsByYear W42814869522023 @default.
• W4281486952 crossrefType "journal-article" @default.
• W4281486952 hasAuthorship W4281486952A5008659449 @default.
• W4281486952 hasAuthorship W4281486952A5013382392 @default.
• W4281486952 hasAuthorship W4281486952A5014672382 @default.
• W4281486952 hasAuthorship W4281486952A5014711277 @default.
• W4281486952 hasAuthorship W4281486952A5020727273 @default.
• W4281486952 hasAuthorship W4281486952A5053463786 @default.
• W4281486952 hasAuthorship W4281486952A5068900082 @default.
• W4281486952 hasAuthorship W4281486952A5072011654 @default.
• W4281486952 hasAuthorship W4281486952A5078143614 @default.
• W4281486952 hasAuthorship W4281486952A5084644971 @default.
• W4281486952 hasBestOaLocation W42814869521 @default.
• W4281486952 hasConcept C121608353 @default.
• W4281486952 hasConcept C126322002 @default.
• W4281486952 hasConcept C141071460 @default.
• W4281486952 hasConcept C207886595 @default.
• W4281486952 hasConcept C2776111594 @default.
• W4281486952 hasConcept C2776694085 @default.
• W4281486952 hasConcept C2780047204 @default.
• W4281486952 hasConcept C2780470880 @default.
• W4281486952 hasConcept C61434518 @default.
• W4281486952 hasConcept C71924100 @default.
• W4281486952 hasConceptScore W4281486952C121608353 @default.
• W4281486952 hasConceptScore W4281486952C126322002 @default.
• W4281486952 hasConceptScore W4281486952C141071460 @default.
• W4281486952 hasConceptScore W4281486952C207886595 @default.
• W4281486952 hasConceptScore W4281486952C2776111594 @default.
• W4281486952 hasConceptScore W4281486952C2776694085 @default.
• W4281486952 hasConceptScore W4281486952C2780047204 @default.
• W4281486952 hasConceptScore W4281486952C2780470880 @default.
• W4281486952 hasConceptScore W4281486952C61434518 @default.
• W4281486952 hasConceptScore W4281486952C71924100 @default.
• W4281486952 hasIssue "5" @default.
• W4281486952 hasLocation W42814869521 @default.
• W4281486952 hasLocation W42814869522 @default.
• W4281486952 hasLocation W42814869523 @default.
• W4281486952 hasOpenAccess W4281486952 @default.
• W4281486952 hasPrimaryLocation W42814869521 @default.
• W4281486952 hasRelatedWork W2014688068 @default.
• W4281486952 hasRelatedWork W2050609593 @default.
• W4281486952 hasRelatedWork W2411853482 @default.
• W4281486952 hasRelatedWork W2412448412 @default.
• W4281486952 hasRelatedWork W2414633359 @default.
• W4281486952 hasRelatedWork W2418395142 @default.

• next