Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281491818> ?p ?o ?g. }
- W4281491818 abstract "This study reports two strategies for preparing O-alkyl derivatives of 6-substituted-4-(trifluoromethyl)pyrimidin-(1H)-ones: a linear protocol of alkylation, using a CCC-building block followed by [3 + 3]-type cyclocondensation with 2-methylisothiourea sulfate and a convergent protocol based on direct alkylation, using 4-(iodomethyl)-2-(methylthio)-6-(trihalomethyl)pyrimidines. It was found that the cyclocondensation strategy is not feasible; thus, the direct chemoselective O-alkylation was performed, and 18 derivatives of the targeted pyrimidines were obtained in 70-98% yields. The structure of the products was unambiguously determined via single crystal X-ray analyses and two-dimensional nuclear magnetic resonance experiments." @default.
- W4281491818 created "2022-05-26" @default.
- W4281491818 creator A5001048702 @default.
- W4281491818 creator A5003745821 @default.
- W4281491818 creator A5045484604 @default.
- W4281491818 creator A5047140133 @default.
- W4281491818 creator A5060048679 @default.
- W4281491818 creator A5067435918 @default.
- W4281491818 date "2022-05-24" @default.
- W4281491818 modified "2023-09-29" @default.
- W4281491818 title "Chemoselective <i>O</i>-Alkylation of 4-(Trifluoromethyl)pyrimidin-2(1<i>H</i>)-ones Using 4-(Iodomethyl)pyrimidines" @default.
- W4281491818 cites W1965484687 @default.
- W4281491818 cites W1966236072 @default.
- W4281491818 cites W1970172272 @default.
- W4281491818 cites W1971393276 @default.
- W4281491818 cites W1997360594 @default.
- W4281491818 cites W2005062578 @default.
- W4281491818 cites W2009556878 @default.
- W4281491818 cites W2017103398 @default.
- W4281491818 cites W2020450416 @default.
- W4281491818 cites W2040555277 @default.
- W4281491818 cites W2049134228 @default.
- W4281491818 cites W2050861035 @default.
- W4281491818 cites W2054975603 @default.
- W4281491818 cites W2059205366 @default.
- W4281491818 cites W2059212997 @default.
- W4281491818 cites W2060526483 @default.
- W4281491818 cites W2071738646 @default.
- W4281491818 cites W2078496466 @default.
- W4281491818 cites W2079876150 @default.
- W4281491818 cites W2083558918 @default.
- W4281491818 cites W2095319881 @default.
- W4281491818 cites W2095455597 @default.
- W4281491818 cites W2098193863 @default.
- W4281491818 cites W2105314926 @default.
- W4281491818 cites W2105673413 @default.
- W4281491818 cites W2142787097 @default.
- W4281491818 cites W2145950951 @default.
- W4281491818 cites W2152227223 @default.
- W4281491818 cites W2167800804 @default.
- W4281491818 cites W2177659439 @default.
- W4281491818 cites W2314794418 @default.
- W4281491818 cites W2340875718 @default.
- W4281491818 cites W2586227998 @default.
- W4281491818 cites W2750639882 @default.
- W4281491818 cites W2752367871 @default.
- W4281491818 cites W2762788515 @default.
- W4281491818 cites W2769596623 @default.
- W4281491818 cites W2774558641 @default.
- W4281491818 cites W2807021797 @default.
- W4281491818 cites W2905148758 @default.
- W4281491818 cites W2916479732 @default.
- W4281491818 cites W2950248725 @default.
- W4281491818 cites W2950839732 @default.
- W4281491818 cites W2950896063 @default.
- W4281491818 cites W2951084971 @default.
- W4281491818 cites W2952157133 @default.
- W4281491818 cites W2952471044 @default.
- W4281491818 cites W2952495566 @default.
- W4281491818 cites W2953128671 @default.
- W4281491818 cites W2953171785 @default.
- W4281491818 cites W2966336835 @default.
- W4281491818 cites W3017217373 @default.
- W4281491818 cites W3087359629 @default.
- W4281491818 cites W3127604451 @default.
- W4281491818 cites W3164972029 @default.
- W4281491818 cites W3183225456 @default.
- W4281491818 cites W4220988668 @default.
- W4281491818 doi "https://doi.org/10.1021/acsomega.2c01925" @default.
- W4281491818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35694463" @default.
- W4281491818 hasPublicationYear "2022" @default.
- W4281491818 type Work @default.
- W4281491818 citedByCount "1" @default.
- W4281491818 countsByYear W42814918182023 @default.
- W4281491818 crossrefType "journal-article" @default.
- W4281491818 hasAuthorship W4281491818A5001048702 @default.
- W4281491818 hasAuthorship W4281491818A5003745821 @default.
- W4281491818 hasAuthorship W4281491818A5045484604 @default.
- W4281491818 hasAuthorship W4281491818A5047140133 @default.
- W4281491818 hasAuthorship W4281491818A5060048679 @default.
- W4281491818 hasAuthorship W4281491818A5067435918 @default.
- W4281491818 hasBestOaLocation W42814918182 @default.
- W4281491818 hasConcept C155647269 @default.
- W4281491818 hasConcept C161790260 @default.
- W4281491818 hasConcept C164361826 @default.
- W4281491818 hasConcept C178790620 @default.
- W4281491818 hasConcept C185592680 @default.
- W4281491818 hasConcept C21951064 @default.
- W4281491818 hasConcept C2524010 @default.
- W4281491818 hasConcept C2776442012 @default.
- W4281491818 hasConcept C2777210771 @default.
- W4281491818 hasConcept C2780263894 @default.
- W4281491818 hasConcept C33923547 @default.
- W4281491818 hasConceptScore W4281491818C155647269 @default.
- W4281491818 hasConceptScore W4281491818C161790260 @default.
- W4281491818 hasConceptScore W4281491818C164361826 @default.
- W4281491818 hasConceptScore W4281491818C178790620 @default.
- W4281491818 hasConceptScore W4281491818C185592680 @default.
- W4281491818 hasConceptScore W4281491818C21951064 @default.
- W4281491818 hasConceptScore W4281491818C2524010 @default.