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• W4281551116 abstract "The outflow tract (OT) regions of the ventricles are a common location of origin for idiopathic ventricular arrhythmias (VA). Non-contact mapping (NCM) with a multi-electrode balloon catheter Ensite-Array enables three-dimensional reconstruction of the geometry of the cardiac chambers and accurate mapping of the propagation map, based on a single beat analysis, facilitating the ablation and contributing procedure success. Assessment of the feasibility and long-term outcomes following NCM-guided OT VA ablation. Single center retrospective analysis of patients admitted for symptomatic OT VA ablation. Demographic and clinical characteristics of patients, procedure data and long-term outcomes were assessed. Fifty-eight patients (79.3% female, age 43.9±17.6 years) were considered, 89.7% without structural heart disease. In 85.7% of the cases left ventricle ejection fraction (LVEF) was preserved (LVEF≥50%), 8.6% had mild systolic dysfunction (LVEF 40%-49%) and 5.7% had moderate systolic dysfunction (LVEF 30%-39%). Twenty-four-hour Holter recording documented sustained VA episodes in 12.1% of the patients, non-sustained VA in 31.0%, and >10 000 premature ventricular complex (PVC)/24 h in 56.9%, with an ECG suggesting right ventricular OT origin in 84.5%. There was total elimination of PVC in 87.9% cases and a significant reduction in 3.4%. During a mean follow-up of 5.5 years, 87.9% patients remained asymptomatic without medication, 12.1% underwent re-ablation due to symptomatic PVC recurrence, and two cases underwent a third successful intervention. Non-contact mapping-guided multi-electrode balloon catheter VA ablation is a highly effective and safe procedure, with a low rate of long-term recurrence. As câmaras de saída (CS) ventriculares são uma localização comum de origem de arritmias ventriculares (AV). O mapeamento não contacto (MNC) por balão multi-elétrodos Ensite-Array permite uma reconstrução geométrica tridimensional das câmaras cardíacas e um mapeamento preciso do mapa de propagação, baseado na análise de um único batimento, facilitando o procedimento de ablação e contribuindo para o seu sucesso. Avaliação da viabilidade e outcomes em longo prazo após ablação de AV da CS guiada por MNC. Análise retrospetiva de pacientes admitidos num único centro para ablação de AV da CS sintomáticas. As caraterísticas demográficas e clínicas dos pacientes, dados do procedimento e outcomes em longo prazo foram avaliados. Foram considerados 58 pacientes (79,3% mulheres, idade 43,9±17,6 anos) foram considerados, 89,7% sem doença cardíaca estrutural. Em 85,7% dos casos a fração de ejeção ventricular esquerda estava preservada (FEVE ≥ 50%), 8,6% tinham disfunção sistólica ligeira (FEVE 40%-49%) e 5,7% tinham disfunção sistólica moderada (FEVE 30%-39%). O Holter 24-horas documentou episódios de AV mantidas em 12,1% dos pacientes, AV não mantidas em 31,0% e >10.000 complexos ectópicos ventriculares (CEV)/24 h em 56,9%, com um ECG sugerindo uma origem na CS ventricular direita em 84,5%. Houve uma total eliminação dos CEV em 87,9% dos casos e uma redução significativa em 3,4%. Durante um follow-up médio de 5,5 anos, 87,9% dos pacientes permaneceram assintomáticos sem medicação, 12,2% foram submetidos a reablação devido a recorrência sintomática de CEV e dois casos fizeram uma terceira intervenção bem-sucedida. A ablação de AV baseada no mapeamento não contacto por balão multi-elétrodos é um procedimento altamente eficaz e seguro, com uma baixa taxa de recorrência em longo prazo." @default.
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• W4281551116 date "2022-05-01" @default.
• W4281551116 modified "2023-10-16" @default.
• W4281551116 title "Long-term outcomes of non-contact multi-electrode balloon catheter mapping-guided ablation of ventricular arrhythmias originating from the outflow tract" @default.
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• W4281551116 doi "https://doi.org/10.1016/j.repc.2021.06.019" @default.
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