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- W4281552425 endingPage "102259" @default.
- W4281552425 startingPage "102259" @default.
- W4281552425 abstract "The orexin (hypocretin) is one of the hypothalamic neuropeptides that plays a critical role in some behaviors including feeding, sleep, arousal, reward processing, and drug addiction. This variety of functions can be described by a united function for orexins in translating states of heightened motivation, for example during physiological requirement states or following exposure to reward opportunities, into planned goal-directed behaviors. An addicted state is characterized by robust activation of orexin neurons from the environment, which triggers downstream circuits to facilitate behavior directed towards obtaining the drug. Two orexin receptors 1 (OX1R) and 2 (OX2R) are widely distributed in the brain. Here, we will introduce and describe the cortical and subcortical brain areas involved in addictive-like behaviors and the impact of orexin on addiction." @default.
- W4281552425 created "2022-05-27" @default.
- W4281552425 creator A5013944286 @default.
- W4281552425 creator A5018763030 @default.
- W4281552425 creator A5054597386 @default.
- W4281552425 creator A5081365706 @default.
- W4281552425 date "2022-10-01" @default.
- W4281552425 modified "2023-10-16" @default.
- W4281552425 title "Neural correlates and potential targets for the contribution of orexin to addiction in cortical and subcortical areas" @default.
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