Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281557225> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4281557225 endingPage "256" @default.
- W4281557225 startingPage "250" @default.
- W4281557225 abstract "Abstract High‐dose chemotherapy followed by autologous stem cell transplantation (auto‐SCT) is the standard treatment for young patient ≤65 years with multiple myeloma (MM). The role of auto‐SCT in elderly patients older than 70 years remains controversial in the era of novel agents and especially since the recent introduction of monoclonal antibodies (AbMo). In this study, we evaluated 12 patients with MM over 70 years old undergoing auto‐SCT (elderly graft cohort) in seven centers of GIMEMA Working Group Lazio. We compared the baseline characteristics, treatment and outcome with 97 MM elderly patients who did not receive auto‐SCT (nontransplant patients) from the same registry who were ≥ 70 years old, but did not undergo auto‐SCT. The median progression free survival (PFS) for graft versus no‐graft cohort was 56.4 versus 26.1 months, respectively. There was a trend for better PFS among graft compared to nontransplant patient (p = .1). On the other hand, the median overall survival for transplant versus nontransplant cohort was 107.6 versus 49.5 months (p = .02). Despite the small number of patients aged ≥70 years and ≤74 years, it seems that auto‐SCT is well tolerated, safe and effective. Therefore, we propose that it should be considered an important treatment option in the era of new drugs in elderly fit patients with MM." @default.
- W4281557225 created "2022-05-27" @default.
- W4281557225 creator A5013821677 @default.
- W4281557225 creator A5017014344 @default.
- W4281557225 creator A5019630321 @default.
- W4281557225 creator A5024751474 @default.
- W4281557225 creator A5029736700 @default.
- W4281557225 creator A5041966654 @default.
- W4281557225 creator A5057173456 @default.
- W4281557225 creator A5059892148 @default.
- W4281557225 creator A5069805862 @default.
- W4281557225 creator A5070129134 @default.
- W4281557225 date "2022-06-22" @default.
- W4281557225 modified "2023-09-30" @default.
- W4281557225 title "Autologous stem cell transplantation in multiple myeloma patients over 70 years: A<scp>GIMEMA</scp>Lazio Working Group experience in a retrospective case–control study" @default.
- W4281557225 cites W1607211057 @default.
- W4281557225 cites W1984490319 @default.
- W4281557225 cites W2013484326 @default.
- W4281557225 cites W2026741469 @default.
- W4281557225 cites W2036828114 @default.
- W4281557225 cites W2056804811 @default.
- W4281557225 cites W2061230659 @default.
- W4281557225 cites W2093274439 @default.
- W4281557225 cites W2102591890 @default.
- W4281557225 cites W2264726996 @default.
- W4281557225 cites W2465127936 @default.
- W4281557225 cites W2604776612 @default.
- W4281557225 cites W2772193704 @default.
- W4281557225 cites W2772946231 @default.
- W4281557225 cites W2944434778 @default.
- W4281557225 cites W2947874495 @default.
- W4281557225 cites W3048700896 @default.
- W4281557225 cites W3119254082 @default.
- W4281557225 cites W3145716452 @default.
- W4281557225 cites W3155243093 @default.
- W4281557225 cites W3156166261 @default.
- W4281557225 cites W3156301562 @default.
- W4281557225 cites W3193935692 @default.
- W4281557225 cites W3203154335 @default.
- W4281557225 cites W577255164 @default.
- W4281557225 doi "https://doi.org/10.1111/ejh.13804" @default.
- W4281557225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35617025" @default.
- W4281557225 hasPublicationYear "2022" @default.
- W4281557225 type Work @default.
- W4281557225 citedByCount "2" @default.
- W4281557225 countsByYear W42815572252022 @default.
- W4281557225 crossrefType "journal-article" @default.
- W4281557225 hasAuthorship W4281557225A5013821677 @default.
- W4281557225 hasAuthorship W4281557225A5017014344 @default.
- W4281557225 hasAuthorship W4281557225A5019630321 @default.
- W4281557225 hasAuthorship W4281557225A5024751474 @default.
- W4281557225 hasAuthorship W4281557225A5029736700 @default.
- W4281557225 hasAuthorship W4281557225A5041966654 @default.
- W4281557225 hasAuthorship W4281557225A5057173456 @default.
- W4281557225 hasAuthorship W4281557225A5059892148 @default.
- W4281557225 hasAuthorship W4281557225A5069805862 @default.
- W4281557225 hasAuthorship W4281557225A5070129134 @default.
- W4281557225 hasConcept C126322002 @default.
- W4281557225 hasConcept C141071460 @default.
- W4281557225 hasConcept C167135981 @default.
- W4281557225 hasConcept C187212893 @default.
- W4281557225 hasConcept C2776364478 @default.
- W4281557225 hasConcept C2776694085 @default.
- W4281557225 hasConcept C2779050716 @default.
- W4281557225 hasConcept C2911091166 @default.
- W4281557225 hasConcept C71924100 @default.
- W4281557225 hasConcept C72563966 @default.
- W4281557225 hasConceptScore W4281557225C126322002 @default.
- W4281557225 hasConceptScore W4281557225C141071460 @default.
- W4281557225 hasConceptScore W4281557225C167135981 @default.
- W4281557225 hasConceptScore W4281557225C187212893 @default.
- W4281557225 hasConceptScore W4281557225C2776364478 @default.
- W4281557225 hasConceptScore W4281557225C2776694085 @default.
- W4281557225 hasConceptScore W4281557225C2779050716 @default.
- W4281557225 hasConceptScore W4281557225C2911091166 @default.
- W4281557225 hasConceptScore W4281557225C71924100 @default.
- W4281557225 hasConceptScore W4281557225C72563966 @default.
- W4281557225 hasIssue "3" @default.
- W4281557225 hasLocation W42815572251 @default.
- W4281557225 hasLocation W42815572252 @default.
- W4281557225 hasOpenAccess W4281557225 @default.
- W4281557225 hasPrimaryLocation W42815572251 @default.
- W4281557225 hasRelatedWork W1818467446 @default.
- W4281557225 hasRelatedWork W2025828169 @default.
- W4281557225 hasRelatedWork W2051392159 @default.
- W4281557225 hasRelatedWork W2435256000 @default.
- W4281557225 hasRelatedWork W2582431155 @default.
- W4281557225 hasRelatedWork W2908722838 @default.
- W4281557225 hasRelatedWork W2998580418 @default.
- W4281557225 hasRelatedWork W3087263577 @default.
- W4281557225 hasRelatedWork W4213285176 @default.
- W4281557225 hasRelatedWork W4242486230 @default.
- W4281557225 hasVolume "109" @default.
- W4281557225 isParatext "false" @default.
- W4281557225 isRetracted "false" @default.
- W4281557225 workType "article" @default.