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- W4281559273 endingPage "104712" @default.
- W4281559273 startingPage "104712" @default.
- W4281559273 abstract "Organisms ranging from plants to higher mammals have developed 24-hour oscillation rhythms to optimize physiology to environmental changes and regulate a plethora of neuroendocrine and behavioral processes, including neurotransmitter and hormone regulation, stress response and learning and memory function. Compelling evidence indicates that a wide array of memory processes is strongly influenced by stress- and emotional arousal-activated neurobiological systems, including the endocannabinoid system which has been extensively shown to play an integral role in mediating stress effects on memory. Here, we review findings showing how circadian rhythms and time-of-day influence stress systems and memory performance. We report evidence of circadian regulation of memory under stress, focusing on the role of the endocannabinoid system and highlighting its circadian rhythmicity. Our discussion illustrates how the endocannabinoid system mediates stress effects on memory in a circadian-dependent fashion. We suggest that endocannabinoids might regulate molecular mechanisms that control memory function under circadian and stress influence, with potential important clinical implications for both neurodevelopmental disorders and psychiatric conditions involving memory impairments." @default.
- W4281559273 created "2022-05-27" @default.
- W4281559273 creator A5019248299 @default.
- W4281559273 creator A5022185376 @default.
- W4281559273 creator A5081647371 @default.
- W4281559273 date "2022-07-01" @default.
- W4281559273 modified "2023-09-23" @default.
- W4281559273 title "Circadian regulation of memory under stress: Endocannabinoids matter" @default.
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