Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281561570> ?p ?o ?g. }
- W4281561570 abstract "The occurrence and development of diabetic nephropathy (DN) are closely related to gut microbiota. Paecilomyces cicadae is a medicinal and edible fungus. Radix astragali is a therapeutic material for unifying Chinese Qi. They can delay the occurrence and development of kidney disease. In recent years, solid-state fermentation of edible fungi and traditional Chinese medicine has become a hot issue. Hypothesis/Gap Statement. We assumed that solid-state fermentation products of R. astragali and Paecilomyces cicadidae (RPF) could ameliorate diabetic nephropathy and modulate gut microbiota composition. We aimed to study the function and mechanism of the RPF for ameliorating DN in mice. We investigated the effect of the potential roles of RPF in DN mice and interaction between DN and gut microbiota using animal experiments and gut microbiota measurements. We found that RPF dramatically reduced urine protein, serum creatinine and blood urea nitrogen in DN mice. Furthermore, RPF ameliorated the physiological condition of DN mice by regulating the abundance of intestinal microbiota such as Ruminococcaceae_UCG-014 , Allobaculum , Unclassified_f__Lachnospiraceae Alloprevotella and Bacteroides . RPF can ameliorate diabetic nephropathy and modulate gut microbiota composition." @default.
- W4281561570 created "2022-05-27" @default.
- W4281561570 creator A5005071507 @default.
- W4281561570 creator A5016010074 @default.
- W4281561570 creator A5021728252 @default.
- W4281561570 creator A5032983325 @default.
- W4281561570 creator A5039100506 @default.
- W4281561570 creator A5039412958 @default.
- W4281561570 creator A5048488410 @default.
- W4281561570 creator A5062133977 @default.
- W4281561570 creator A5068605641 @default.
- W4281561570 creator A5089007155 @default.
- W4281561570 date "2022-05-26" @default.
- W4281561570 modified "2023-09-24" @default.
- W4281561570 title "Paecilomyces cicadae-fermented Radix astragali ameliorate diabetic nephropathy in mice by modulating the gut microbiota" @default.
- W4281561570 cites W1672110167 @default.
- W4281561570 cites W1972686367 @default.
- W4281561570 cites W1999500451 @default.
- W4281561570 cites W2046296664 @default.
- W4281561570 cites W2053039168 @default.
- W4281561570 cites W2054194835 @default.
- W4281561570 cites W2086275477 @default.
- W4281561570 cites W2095854550 @default.
- W4281561570 cites W2108702111 @default.
- W4281561570 cites W2118987172 @default.
- W4281561570 cites W2135989088 @default.
- W4281561570 cites W2149573313 @default.
- W4281561570 cites W2149711855 @default.
- W4281561570 cites W2150350691 @default.
- W4281561570 cites W2162454095 @default.
- W4281561570 cites W2275810086 @default.
- W4281561570 cites W2596939106 @default.
- W4281561570 cites W2604727490 @default.
- W4281561570 cites W2608753124 @default.
- W4281561570 cites W2738598016 @default.
- W4281561570 cites W2774633776 @default.
- W4281561570 cites W2799300982 @default.
- W4281561570 cites W2799381775 @default.
- W4281561570 cites W2801275609 @default.
- W4281561570 cites W2904387867 @default.
- W4281561570 cites W2905103360 @default.
- W4281561570 cites W2914244078 @default.
- W4281561570 cites W2938586145 @default.
- W4281561570 cites W2942080882 @default.
- W4281561570 cites W2953704411 @default.
- W4281561570 cites W2966228008 @default.
- W4281561570 cites W2968199413 @default.
- W4281561570 cites W2990492011 @default.
- W4281561570 cites W3002773615 @default.
- W4281561570 cites W3027329600 @default.
- W4281561570 doi "https://doi.org/10.1099/jmm.0.001535" @default.
- W4281561570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35617337" @default.
- W4281561570 hasPublicationYear "2022" @default.
- W4281561570 type Work @default.
- W4281561570 citedByCount "0" @default.
- W4281561570 crossrefType "journal-article" @default.
- W4281561570 hasAuthorship W4281561570A5005071507 @default.
- W4281561570 hasAuthorship W4281561570A5016010074 @default.
- W4281561570 hasAuthorship W4281561570A5021728252 @default.
- W4281561570 hasAuthorship W4281561570A5032983325 @default.
- W4281561570 hasAuthorship W4281561570A5039100506 @default.
- W4281561570 hasAuthorship W4281561570A5039412958 @default.
- W4281561570 hasAuthorship W4281561570A5048488410 @default.
- W4281561570 hasAuthorship W4281561570A5062133977 @default.
- W4281561570 hasAuthorship W4281561570A5068605641 @default.
- W4281561570 hasAuthorship W4281561570A5089007155 @default.
- W4281561570 hasConcept C104317684 @default.
- W4281561570 hasConcept C134018914 @default.
- W4281561570 hasConcept C203014093 @default.
- W4281561570 hasConcept C2777695942 @default.
- W4281561570 hasConcept C2778168646 @default.
- W4281561570 hasConcept C2779704485 @default.
- W4281561570 hasConcept C2779922275 @default.
- W4281561570 hasConcept C2780091579 @default.
- W4281561570 hasConcept C2781184683 @default.
- W4281561570 hasConcept C42062724 @default.
- W4281561570 hasConcept C523546767 @default.
- W4281561570 hasConcept C539455810 @default.
- W4281561570 hasConcept C54355233 @default.
- W4281561570 hasConcept C55493867 @default.
- W4281561570 hasConcept C555293320 @default.
- W4281561570 hasConcept C86803240 @default.
- W4281561570 hasConcept C98274493 @default.
- W4281561570 hasConceptScore W4281561570C104317684 @default.
- W4281561570 hasConceptScore W4281561570C134018914 @default.
- W4281561570 hasConceptScore W4281561570C203014093 @default.
- W4281561570 hasConceptScore W4281561570C2777695942 @default.
- W4281561570 hasConceptScore W4281561570C2778168646 @default.
- W4281561570 hasConceptScore W4281561570C2779704485 @default.
- W4281561570 hasConceptScore W4281561570C2779922275 @default.
- W4281561570 hasConceptScore W4281561570C2780091579 @default.
- W4281561570 hasConceptScore W4281561570C2781184683 @default.
- W4281561570 hasConceptScore W4281561570C42062724 @default.
- W4281561570 hasConceptScore W4281561570C523546767 @default.
- W4281561570 hasConceptScore W4281561570C539455810 @default.
- W4281561570 hasConceptScore W4281561570C54355233 @default.
- W4281561570 hasConceptScore W4281561570C55493867 @default.
- W4281561570 hasConceptScore W4281561570C555293320 @default.
- W4281561570 hasConceptScore W4281561570C86803240 @default.
- W4281561570 hasConceptScore W4281561570C98274493 @default.