Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281621501> ?p ?o ?g. }
- W4281621501 abstract "Type 2 diabetes mellitus (T2DM) increases the risk of worse long-term outcomes in patients with non-ischemic dilated cardiomyopathy (NIDCM). However, the additive effects of T2DM on left ventricular (LV) function in NIDCM remain unclear. Accordingly, we aimed to investigate the impact of comorbid T2DM on LV deformation in NIDCM individuals.Three hundred forty-two NIDCM patients without T2DM [NIDCM (T2DM-)], 93 with T2DM [NIDCM (T2DM+)] and 80 age- and sex-matched normal controls who underwent cardiac magnetic resonance scanning were included. LV geometry, function, and LV global strains, including peak strain (PS), peak systolic strain rate (PSSR) and peak diastolic strain rate (PDSR) in the radial, circumferential and longitudinal directions, were measured. NIDCM (T2DM+) patients were divided into two subgroups based on the HbA1c level (< 7.0% and ≥ 7.0%). The determinants of reduced LV myocardial strain for all NIDCM individuals and NIDCM (T2DM+) patients were assessed using multivariable linear regression analyses.Compared with normal controls, both NIDCM (T2DM -) and NIDCM (T2DM+) patients exhibited increased LV end-diastolic and end-systolic volume index and decreased LV ejection fraction. LV global strains progressively declined from the normal controls to the NIDCM (T2DM-) group to the NIDCM (T2DM+) group (all p < 0.017), except for radial PDSR and PSSR. Subgroup analysis showed that LV global radial PS and longitudinal PS, PSSR-L and PDSR-L were worse in NIDCM patients with poor glycemic control than in those with good glycemic control (p < 0.017). T2DM was an independent determinant of reduced LV global circumferential PS and longitudinal PS in patients with NIDCM (both p < 0.05). An increased HbA1c level was independently associated with a decreased global radial PS (β = - 0.285, p < 0.01) and longitudinal PS (β = 0.320, p < 0.01) in NIDCM (T2DM+) patients.T2DM has an additive deleterious effect on LV systolic and diastolic function in NIDCM patients. Among NIDCM patients with T2DM, HbA1c was found to be associated with reduced LV myocardial strain." @default.
- W4281621501 created "2022-06-13" @default.
- W4281621501 creator A5020100539 @default.
- W4281621501 creator A5026345757 @default.
- W4281621501 creator A5037188418 @default.
- W4281621501 creator A5046600167 @default.
- W4281621501 creator A5047030842 @default.
- W4281621501 creator A5057135582 @default.
- W4281621501 creator A5088757206 @default.
- W4281621501 date "2022-06-04" @default.
- W4281621501 modified "2023-10-13" @default.
- W4281621501 title "Impact of type 2 diabetes mellitus on left ventricular deformation in non-ischemic dilated cardiomyopathy patients assessed by cardiac magnetic resonance imaging" @default.
- W4281621501 cites W1489130191 @default.
- W4281621501 cites W1810825951 @default.
- W4281621501 cites W1821804635 @default.
- W4281621501 cites W1966815453 @default.
- W4281621501 cites W1971093878 @default.
- W4281621501 cites W1987229393 @default.
- W4281621501 cites W2007398545 @default.
- W4281621501 cites W2039943743 @default.
- W4281621501 cites W2043926420 @default.
- W4281621501 cites W2051082763 @default.
- W4281621501 cites W2051608025 @default.
- W4281621501 cites W2054005523 @default.
- W4281621501 cites W2100336830 @default.
- W4281621501 cites W2120934972 @default.
- W4281621501 cites W2123640306 @default.
- W4281621501 cites W2263251763 @default.
- W4281621501 cites W2282571861 @default.
- W4281621501 cites W2292946576 @default.
- W4281621501 cites W2335788856 @default.
- W4281621501 cites W2525284752 @default.
- W4281621501 cites W2541421079 @default.
- W4281621501 cites W2780741330 @default.
- W4281621501 cites W2791670199 @default.
- W4281621501 cites W2792805849 @default.
- W4281621501 cites W2809812205 @default.
- W4281621501 cites W2917743074 @default.
- W4281621501 cites W2964946260 @default.
- W4281621501 cites W3022620965 @default.
- W4281621501 cites W3032289146 @default.
- W4281621501 cites W3034347219 @default.
- W4281621501 cites W3035079254 @default.
- W4281621501 cites W3122992747 @default.
- W4281621501 cites W3137002396 @default.
- W4281621501 cites W3179529940 @default.
- W4281621501 cites W3204656588 @default.
- W4281621501 cites W3210081391 @default.
- W4281621501 doi "https://doi.org/10.1186/s12933-022-01533-5" @default.
- W4281621501 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35659302" @default.
- W4281621501 hasPublicationYear "2022" @default.
- W4281621501 type Work @default.
- W4281621501 citedByCount "2" @default.
- W4281621501 countsByYear W42816215012023 @default.
- W4281621501 crossrefType "journal-article" @default.
- W4281621501 hasAuthorship W4281621501A5020100539 @default.
- W4281621501 hasAuthorship W4281621501A5026345757 @default.
- W4281621501 hasAuthorship W4281621501A5037188418 @default.
- W4281621501 hasAuthorship W4281621501A5046600167 @default.
- W4281621501 hasAuthorship W4281621501A5047030842 @default.
- W4281621501 hasAuthorship W4281621501A5057135582 @default.
- W4281621501 hasAuthorship W4281621501A5088757206 @default.
- W4281621501 hasBestOaLocation W42816215011 @default.
- W4281621501 hasConcept C126322002 @default.
- W4281621501 hasConcept C126838900 @default.
- W4281621501 hasConcept C134018914 @default.
- W4281621501 hasConcept C143409427 @default.
- W4281621501 hasConcept C164705383 @default.
- W4281621501 hasConcept C2776383484 @default.
- W4281621501 hasConcept C2776553924 @default.
- W4281621501 hasConcept C2778198053 @default.
- W4281621501 hasConcept C2778797674 @default.
- W4281621501 hasConcept C2779306644 @default.
- W4281621501 hasConcept C2780473172 @default.
- W4281621501 hasConcept C2910068830 @default.
- W4281621501 hasConcept C555293320 @default.
- W4281621501 hasConcept C71924100 @default.
- W4281621501 hasConcept C78085059 @default.
- W4281621501 hasConceptScore W4281621501C126322002 @default.
- W4281621501 hasConceptScore W4281621501C126838900 @default.
- W4281621501 hasConceptScore W4281621501C134018914 @default.
- W4281621501 hasConceptScore W4281621501C143409427 @default.
- W4281621501 hasConceptScore W4281621501C164705383 @default.
- W4281621501 hasConceptScore W4281621501C2776383484 @default.
- W4281621501 hasConceptScore W4281621501C2776553924 @default.
- W4281621501 hasConceptScore W4281621501C2778198053 @default.
- W4281621501 hasConceptScore W4281621501C2778797674 @default.
- W4281621501 hasConceptScore W4281621501C2779306644 @default.
- W4281621501 hasConceptScore W4281621501C2780473172 @default.
- W4281621501 hasConceptScore W4281621501C2910068830 @default.
- W4281621501 hasConceptScore W4281621501C555293320 @default.
- W4281621501 hasConceptScore W4281621501C71924100 @default.
- W4281621501 hasConceptScore W4281621501C78085059 @default.
- W4281621501 hasFunder F4320321001 @default.
- W4281621501 hasIssue "1" @default.
- W4281621501 hasLocation W42816215011 @default.
- W4281621501 hasLocation W42816215012 @default.
- W4281621501 hasLocation W42816215013 @default.
- W4281621501 hasOpenAccess W4281621501 @default.
- W4281621501 hasPrimaryLocation W42816215011 @default.