FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281633384> ?p ?o ?g. }

• W4281633384 endingPage "156571" @default.
• W4281633384 startingPage "156571" @default.
• W4281633384 abstract "Microplastics (MPs) pollution has been recognized as a threat to sustainable fisheries due to the risks of MPs contamination in the process of feed production and susceptibility of fish to ingest MPs from the aquatic environment. In this study, we applied comprehensive approaches to investigate the impacts of polyethylene microplastics (PE-MPs) on juvenile genetically improved farmed tilapia (GIFT, Oreochromis niloticus) through 9-week dietary exposure based on growth performance, gut microbiota, liver metabolism, and gene expressions in brain and liver tissues. Dietary exposure to two kinds of PE-MPs with different median size (27 μm and 63 μm, respectively) concentration-dependently decreased weight gain (WG), while increased feed conversion ratio (FCR) and hepatosomatic index (HSI) of the tilapia. Dietary administration of PE-MPs also significantly reduced the activities of intestinal protease and amylase. PE-MPs particles of the larger size groups (63 μm) were mainly detected in feces, but those of the smaller ones (27 μm) tended to be accumulated in intestine. PE-MPs ingestion resulted in the alteration of gut microbiota composition, with Fusobacteria, Verrucomicrobia and Firmicutes as the overrepresented bacterial taxa. Metabolomic assays of liver samples in fish fed the diets containing 8 % of PE-MPs revealed the particle size-specific variations in composition of differential metabolites and metabolism pathways such as amino acid and glycerophospholipid metabolism. Gene expressions of brain and liver samples were analyzed by RNA-seq. Photoperiodism and circadian rhythm were the representative biological processes enriched for the differentially expressed genes (DEGs) identified from the brain. Citrate cycle (TCA cycle) was the most enriched pathway revealed by a joint transcriptomic and metabolic pathway analysis for the liver, followed by propanoate and pyruvate metabolism. Furthermore, an integration analysis of the gut microbiome and liver transcriptome data identified significant associations between several pathogenic bacteria taxa and immune pathways. Our findings demonstrated that the sizes and concentrations of PE-MPs are critically related to their toxic impacts on microbiota community, metabolism, gene expressions and thus fish growth." @default.
• W4281633384 created "2022-06-13" @default.
• W4281633384 creator A5001037240 @default.
• W4281633384 creator A5003122975 @default.
• W4281633384 creator A5006492283 @default.
• W4281633384 creator A5015196785 @default.
• W4281633384 creator A5016356014 @default.
• W4281633384 creator A5029410827 @default.
• W4281633384 creator A5031455285 @default.
• W4281633384 creator A5041320129 @default.
• W4281633384 creator A5048769431 @default.
• W4281633384 creator A5056199079 @default.
• W4281633384 creator A5061199142 @default.
• W4281633384 creator A5069836102 @default.
• W4281633384 creator A5079376185 @default.
• W4281633384 date "2022-10-01" @default.
• W4281633384 modified "2023-10-16" @default.
• W4281633384 title "Comprehensive understanding the impacts of dietary exposure to polyethylene microplastics on genetically improved farmed tilapia (Oreochromis niloticus): tracking from growth, microbiota, metabolism to gene expressions" @default.
• W4281633384 cites W1617495083 @default.
• W4281633384 cites W1907916733 @default.
• W4281633384 cites W1988925586 @default.
• W4281633384 cites W1995543670 @default.
• W4281633384 cites W2003022112 @default.
• W4281633384 cites W2009120022 @default.
• W4281633384 cites W2023831182 @default.
• W4281633384 cites W2037496050 @default.
• W4281633384 cites W2081465448 @default.
• W4281633384 cites W2103747630 @default.
• W4281633384 cites W2105423509 @default.
• W4281633384 cites W2117023110 @default.
• W4281633384 cites W2143362587 @default.
• W4281633384 cites W2146074997 @default.
• W4281633384 cites W2159675211 @default.
• W4281633384 cites W2169589032 @default.
• W4281633384 cites W2341820027 @default.
• W4281633384 cites W2401404581 @default.
• W4281633384 cites W2554494350 @default.
• W4281633384 cites W2619963141 @default.
• W4281633384 cites W2620099204 @default.
• W4281633384 cites W2737217596 @default.
• W4281633384 cites W2765421460 @default.
• W4281633384 cites W2766101344 @default.
• W4281633384 cites W2781826559 @default.
• W4281633384 cites W2793554595 @default.
• W4281633384 cites W2886520930 @default.
• W4281633384 cites W2891272139 @default.
• W4281633384 cites W2898009306 @default.
• W4281633384 cites W2901527430 @default.
• W4281633384 cites W2903156431 @default.
• W4281633384 cites W2914833654 @default.
• W4281633384 cites W2929923000 @default.
• W4281633384 cites W2941165419 @default.
• W4281633384 cites W2941515856 @default.
• W4281633384 cites W2944329833 @default.
• W4281633384 cites W2945027391 @default.
• W4281633384 cites W2948033630 @default.
• W4281633384 cites W2952176950 @default.
• W4281633384 cites W2963276645 @default.
• W4281633384 cites W2966347422 @default.
• W4281633384 cites W2981438318 @default.
• W4281633384 cites W2984641305 @default.
• W4281633384 cites W3005753228 @default.
• W4281633384 cites W3017202774 @default.
• W4281633384 cites W3018789581 @default.
• W4281633384 cites W3022235137 @default.
• W4281633384 cites W3022998514 @default.
• W4281633384 cites W3049028620 @default.
• W4281633384 cites W3089110361 @default.
• W4281633384 cites W3092545627 @default.
• W4281633384 cites W3092713087 @default.
• W4281633384 cites W3097928199 @default.
• W4281633384 cites W3105133030 @default.
• W4281633384 cites W3110054816 @default.
• W4281633384 cites W3115071795 @default.
• W4281633384 cites W3122117959 @default.
• W4281633384 cites W3127517865 @default.
• W4281633384 cites W3130946532 @default.
• W4281633384 cites W3132603121 @default.
• W4281633384 cites W3134935511 @default.
• W4281633384 cites W3136411848 @default.
• W4281633384 cites W3146788924 @default.
• W4281633384 cites W3150474329 @default.
• W4281633384 cites W3152813579 @default.
• W4281633384 cites W3159995035 @default.
• W4281633384 cites W3181934357 @default.
• W4281633384 cites W3205733811 @default.
• W4281633384 cites W4210329662 @default.
• W4281633384 cites W4280587540 @default.
• W4281633384 doi "https://doi.org/10.1016/j.scitotenv.2022.156571" @default.
• W4281633384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35688245" @default.
• W4281633384 hasPublicationYear "2022" @default.
• W4281633384 type Work @default.
• W4281633384 citedByCount "8" @default.
• W4281633384 countsByYear W42816333842022 @default.
• W4281633384 countsByYear W42816333842023 @default.
• W4281633384 crossrefType "journal-article" @default.
• W4281633384 hasAuthorship W4281633384A5001037240 @default.
• W4281633384 hasAuthorship W4281633384A5003122975 @default.

• next