FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281652016> ?p ?o ?g. }

• W4281652016 abstract "The incidence of tularemia has recently increased throughout Europe. Pediatric tularemia typically presents with ulceroglandular or glandular disease and requires antimicrobial therapy not used in the empirical management of childhood acute lymphadenitis. We describe the clinical presentation and course in a case series comprising 20 patients.This is a retrospective analysis of a single-center case series of microbiologically confirmed tularemia in patients <16 years of age diagnosed between 2010 and 2021.Nineteen patients (95%) presented with ulceroglandular (n = 14) or glandular disease (n = 5), respectively. A characteristic entry site lesion (eschar) was present in 14 (74%). Fever was present at illness onset in 15 patients (75%) and disappeared in all patients before targeted therapy was initiated. The diagnosis was confirmed by serology in 18 patients (90%). While immunochromatography was positive as early as on day 7, a microagglutination test titer 1:≥160 was found no earlier than on day 13. Sixteen patients (80%) were initially treated with an antimicrobial agent ineffective against F. tularensis. The median delay (range) from illness onset to initiation of targeted therapy was 12 (6-40) days. Surgical incision and drainage were ultimately performed in 12 patients (60%).Pediatric tularemia in Switzerland usually presents with early, self-limiting fever and a characteristic entry site lesion with regional lymphadenopathy draining the scalp or legs. Particularly in association with a tick exposure history, this presentation may allow early first-line therapy with an agent specifically targeting F. tularensis, potentially obviating the need for surgical therapy." @default.
• W4281652016 created "2022-06-13" @default.
• W4281652016 creator A5009559850 @default.
• W4281652016 creator A5017550230 @default.
• W4281652016 creator A5045479053 @default.
• W4281652016 creator A5052791618 @default.
• W4281652016 creator A5079523694 @default.
• W4281652016 creator A5082054723 @default.
• W4281652016 creator A5082417498 @default.
• W4281652016 creator A5084264424 @default.
• W4281652016 creator A5091281566 @default.
• W4281652016 date "2022-06-11" @default.
• W4281652016 modified "2023-10-05" @default.
• W4281652016 title "Pediatric Tularemia—A Case Series From a Single Center in Switzerland" @default.
• W4281652016 cites W125909366 @default.
• W4281652016 cites W1975239204 @default.
• W4281652016 cites W1990912380 @default.
• W4281652016 cites W1993180997 @default.
• W4281652016 cites W1999488299 @default.
• W4281652016 cites W2017174215 @default.
• W4281652016 cites W2020301583 @default.
• W4281652016 cites W2033872995 @default.
• W4281652016 cites W2036783575 @default.
• W4281652016 cites W2047822804 @default.
• W4281652016 cites W2055255507 @default.
• W4281652016 cites W2059107560 @default.
• W4281652016 cites W2068992857 @default.
• W4281652016 cites W2071590885 @default.
• W4281652016 cites W2073969833 @default.
• W4281652016 cites W2085044529 @default.
• W4281652016 cites W2086165973 @default.
• W4281652016 cites W2119398406 @default.
• W4281652016 cites W2125739051 @default.
• W4281652016 cites W2128732404 @default.
• W4281652016 cites W2129329210 @default.
• W4281652016 cites W2130545727 @default.
• W4281652016 cites W2131148090 @default.
• W4281652016 cites W2131612579 @default.
• W4281652016 cites W2135676710 @default.
• W4281652016 cites W2144993686 @default.
• W4281652016 cites W2209488973 @default.
• W4281652016 cites W2332052962 @default.
• W4281652016 cites W2406855382 @default.
• W4281652016 cites W2605948848 @default.
• W4281652016 cites W2609516802 @default.
• W4281652016 cites W2785764054 @default.
• W4281652016 cites W2789664868 @default.
• W4281652016 cites W2802457263 @default.
• W4281652016 cites W2910671553 @default.
• W4281652016 cites W2944056928 @default.
• W4281652016 cites W2958666821 @default.
• W4281652016 cites W2989259251 @default.
• W4281652016 cites W3088442014 @default.
• W4281652016 cites W3090590860 @default.
• W4281652016 cites W3092688052 @default.
• W4281652016 cites W3097276306 @default.
• W4281652016 cites W3136727513 @default.
• W4281652016 cites W3200241037 @default.
• W4281652016 cites W3201482987 @default.
• W4281652016 cites W342222860 @default.
• W4281652016 cites W4206748152 @default.
• W4281652016 cites W4211067865 @default.
• W4281652016 cites W4429191 @default.
• W4281652016 doi "https://doi.org/10.1093/ofid/ofac292" @default.
• W4281652016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35873298" @default.
• W4281652016 hasPublicationYear "2022" @default.
• W4281652016 type Work @default.
• W4281652016 citedByCount "1" @default.
• W4281652016 countsByYear W42816520162023 @default.
• W4281652016 crossrefType "journal-article" @default.
• W4281652016 hasAuthorship W4281652016A5009559850 @default.
• W4281652016 hasAuthorship W4281652016A5017550230 @default.
• W4281652016 hasAuthorship W4281652016A5045479053 @default.
• W4281652016 hasAuthorship W4281652016A5052791618 @default.
• W4281652016 hasAuthorship W4281652016A5079523694 @default.
• W4281652016 hasAuthorship W4281652016A5082054723 @default.
• W4281652016 hasAuthorship W4281652016A5082417498 @default.
• W4281652016 hasAuthorship W4281652016A5084264424 @default.
• W4281652016 hasAuthorship W4281652016A5091281566 @default.
• W4281652016 hasBestOaLocation W42816520161 @default.
• W4281652016 hasConcept C101265243 @default.
• W4281652016 hasConcept C104317684 @default.
• W4281652016 hasConcept C120665830 @default.
• W4281652016 hasConcept C121332964 @default.
• W4281652016 hasConcept C141071460 @default.
• W4281652016 hasConcept C142724271 @default.
• W4281652016 hasConcept C159654299 @default.
• W4281652016 hasConcept C16005928 @default.
• W4281652016 hasConcept C185592680 @default.
• W4281652016 hasConcept C187212893 @default.
• W4281652016 hasConcept C203014093 @default.
• W4281652016 hasConcept C204787440 @default.
• W4281652016 hasConcept C2775983634 @default.
• W4281652016 hasConcept C2778907293 @default.
• W4281652016 hasConcept C2780206043 @default.
• W4281652016 hasConcept C2780467176 @default.
• W4281652016 hasConcept C45189115 @default.
• W4281652016 hasConcept C501593827 @default.
• W4281652016 hasConcept C55493867 @default.
• W4281652016 hasConcept C60987743 @default.

• next