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• W4281664119 abstract "Heart failure (HF) is a structural, functional cardiac abnormality that causes elevated intracardiac pressure or inadequate cardiac output [ [1] McDonagh T.A. Metra M. Adamo M. Gardner R.S. Baumbach A. Böhm M. et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur. Heart J. 2021; 42: 3599-3726https://doi.org/10.1093/eurheartj/ehab368 Crossref PubMed Scopus (1648) Google Scholar ]. Identifying the etiology of the underlying cardiac dysfunction is crucial to allow adequate treatment [ [1] McDonagh T.A. Metra M. Adamo M. Gardner R.S. Baumbach A. Böhm M. et al. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur. Heart J. 2021; 42: 3599-3726https://doi.org/10.1093/eurheartj/ehab368 Crossref PubMed Scopus (1648) Google Scholar ]. Sex affects the epidemiology, risk factors, pathophysiology, phenotypes, and outcomes of HF (Fig. 1) [ [2] Lam C.S.P. Arnott C. Beale A.L. Chandramouli C. Hilfiker-Kleiner D. Kaye D.M. et al. Sex differences in heart failure. Eur. Heart J. 2019; 40: 3859-3868chttps://doi.org/10.1093/eurheartj/ehz835 Crossref PubMed Scopus (178) Google Scholar ]. HF with reduced ejection fraction (EF) (HFrEF) is more prevalent in men, whereas HF with preserved ejection fraction (HFpEF) is more often observed in women [ [3] Regitz-Zagrosek V. Sex and gender differences in heart failure. Int. J. Heart Fail. 2020; 2: 157-181https://doi.org/10.36628/ijhf.2020.0004 Crossref Google Scholar ]. Furthermore, women are more likely to experience breast cancer-related cardiomyopathy and/or peripartum cardiomyopathy, whereas men are at a higher risk of sudden cardiac arrest and/or ischemic cardiomyopathy [ [2] Lam C.S.P. Arnott C. Beale A.L. Chandramouli C. Hilfiker-Kleiner D. Kaye D.M. et al. Sex differences in heart failure. Eur. Heart J. 2019; 40: 3859-3868chttps://doi.org/10.1093/eurheartj/ehz835 Crossref PubMed Scopus (178) Google Scholar , [3] Regitz-Zagrosek V. Sex and gender differences in heart failure. Int. J. Heart Fail. 2020; 2: 157-181https://doi.org/10.36628/ijhf.2020.0004 Crossref Google Scholar ]. Takotsubo cardiomyopathy also has a female predominance (female-to-male ratio, 9:1). Genetic cardiomyopathies often exhibit sex-related differences in penetrance [ [2] Lam C.S.P. Arnott C. Beale A.L. Chandramouli C. Hilfiker-Kleiner D. Kaye D.M. et al. Sex differences in heart failure. Eur. Heart J. 2019; 40: 3859-3868chttps://doi.org/10.1093/eurheartj/ehz835 Crossref PubMed Scopus (178) Google Scholar ]. Sex-related differences among young adults with heart failure in SwedenInternational Journal of CardiologyVol. 362PreviewDifferences between the sexes among the non-elderly with heart failure (HF) have been insufficiently evaluated. This study aims to investigate sex-related differences in early-onset HF. Full-Text PDF" @default.
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• W4281664119 date "2022-10-01" @default.
• W4281664119 modified "2023-09-25" @default.
• W4281664119 title "Sex-related differences among young adults with heart failure: Does sex matter?" @default.
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• W4281664119 doi "https://doi.org/10.1016/j.ijcard.2022.05.062" @default.
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