Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281673766> ?p ?o ?g. }
- W4281673766 abstract "Over the past two decades, unique and comprehensive cancer treatment has ushered new hope in the holistic management of the disease. Cancer immunotherapy, which harnesses the immune system of the patient to attack the cancer cells in a targeted manner, scores over others by being less debilitating compared to the existing treatment strategies. Significant advancements in the knowledge of immune surveillance in the last few decades have led to the development of several types of immune therapy like monoclonal antibodies, cancer vaccines, immune checkpoint inhibitors, T-cell transfer therapy or adoptive cell therapy (ACT) and immune system modulators. Intensive research has established cancer immunotherapy to be a safe and effective method for improving survival and the quality of a patient’s life. However, numerous issues with respect to site-specific delivery, resistance to immunotherapy, and escape of cancer cells from immune responses, need to be addressed for expanding and utilizing this therapy as a regular mode in the clinical treatment. Development in the field of nanotechnology has augmented the therapeutic efficiency of treatment modalities of immunotherapy. Nanocarriers could be used as vehicles because of their advantages such as increased surface areas, targeted delivery, controlled surface and release chemistry, enhanced permeation and retention effect, etc. They could enhance the function of immune cells by incorporating immunomodulatory agents that influence the tumor microenvironment, thus enabling antitumor immunity. Robust validation of the combined effect of nanotechnology and immunotherapy techniques in the clinics has paved the way for a better treatment option for cancer than the already existing procedures such as chemotherapy and radiotherapy. In this review, we discuss the current applications of nanoparticles in the development of ‘smart’ cancer immunotherapeutic agents like ACT, cancer vaccines, monoclonal antibodies, their site-specific delivery, and modulation of other endogenous immune cells. We also highlight the immense possibilities of using nanotechnology to accomplish leveraging the coordinated and adaptive immune system of a patient to tackle the complexity of treating unique disease conditions and provide future prospects in the field of cancer immunotherapy." @default.
- W4281673766 created "2022-06-13" @default.
- W4281673766 creator A5057599185 @default.
- W4281673766 creator A5060133330 @default.
- W4281673766 creator A5080022344 @default.
- W4281673766 creator A5086010447 @default.
- W4281673766 date "2022-06-08" @default.
- W4281673766 modified "2023-10-16" @default.
- W4281673766 title "Tracing New Landscapes in the Arena of Nanoparticle-Based Cancer Immunotherapy" @default.
- W4281673766 cites W1483194800 @default.
- W4281673766 cites W1550626755 @default.
- W4281673766 cites W1570644230 @default.
- W4281673766 cites W1600015917 @default.
- W4281673766 cites W1683956275 @default.
- W4281673766 cites W1913328895 @default.
- W4281673766 cites W1924252729 @default.
- W4281673766 cites W1927075449 @default.
- W4281673766 cites W1963991141 @default.
- W4281673766 cites W1965979673 @default.
- W4281673766 cites W1966347675 @default.
- W4281673766 cites W1971416592 @default.
- W4281673766 cites W1976915466 @default.
- W4281673766 cites W1978640331 @default.
- W4281673766 cites W1979835088 @default.
- W4281673766 cites W1982902233 @default.
- W4281673766 cites W1983412131 @default.
- W4281673766 cites W1988789252 @default.
- W4281673766 cites W1990338386 @default.
- W4281673766 cites W1990602451 @default.
- W4281673766 cites W1992909341 @default.
- W4281673766 cites W1994993231 @default.
- W4281673766 cites W2000266809 @default.
- W4281673766 cites W2006729360 @default.
- W4281673766 cites W2007894099 @default.
- W4281673766 cites W2008039399 @default.
- W4281673766 cites W2014760202 @default.
- W4281673766 cites W2015164743 @default.
- W4281673766 cites W2016829755 @default.
- W4281673766 cites W2025989684 @default.
- W4281673766 cites W2026571103 @default.
- W4281673766 cites W2030712838 @default.
- W4281673766 cites W2033278321 @default.
- W4281673766 cites W2036050007 @default.
- W4281673766 cites W2036627567 @default.
- W4281673766 cites W2039938599 @default.
- W4281673766 cites W2040237389 @default.
- W4281673766 cites W2044835625 @default.
- W4281673766 cites W2045226967 @default.
- W4281673766 cites W2048357750 @default.
- W4281673766 cites W2050216284 @default.
- W4281673766 cites W2050417053 @default.
- W4281673766 cites W2050632372 @default.
- W4281673766 cites W2052382519 @default.
- W4281673766 cites W2054410308 @default.
- W4281673766 cites W2057874822 @default.
- W4281673766 cites W2070660250 @default.
- W4281673766 cites W2073948759 @default.
- W4281673766 cites W2074272681 @default.
- W4281673766 cites W2076226743 @default.
- W4281673766 cites W2079554681 @default.
- W4281673766 cites W2080528582 @default.
- W4281673766 cites W2081030263 @default.
- W4281673766 cites W2083500661 @default.
- W4281673766 cites W2086073469 @default.
- W4281673766 cites W2087013294 @default.
- W4281673766 cites W2087979436 @default.
- W4281673766 cites W2088027633 @default.
- W4281673766 cites W2088317237 @default.
- W4281673766 cites W2090360437 @default.
- W4281673766 cites W2090872648 @default.
- W4281673766 cites W2096295815 @default.
- W4281673766 cites W2096322385 @default.
- W4281673766 cites W2097492202 @default.
- W4281673766 cites W2098414192 @default.
- W4281673766 cites W2099965474 @default.
- W4281673766 cites W2109386630 @default.
- W4281673766 cites W2113302343 @default.
- W4281673766 cites W2113588421 @default.
- W4281673766 cites W2115583652 @default.
- W4281673766 cites W2118083360 @default.
- W4281673766 cites W2120350838 @default.
- W4281673766 cites W2120377744 @default.
- W4281673766 cites W2122718122 @default.
- W4281673766 cites W2124514746 @default.
- W4281673766 cites W2125439441 @default.
- W4281673766 cites W2126043466 @default.
- W4281673766 cites W2130166533 @default.
- W4281673766 cites W2130830673 @default.
- W4281673766 cites W2132923173 @default.
- W4281673766 cites W2134638467 @default.
- W4281673766 cites W2135561906 @default.
- W4281673766 cites W2137289789 @default.
- W4281673766 cites W2138715808 @default.
- W4281673766 cites W2139169365 @default.
- W4281673766 cites W2143026251 @default.
- W4281673766 cites W2143163879 @default.
- W4281673766 cites W2143749967 @default.
- W4281673766 cites W2150692883 @default.
- W4281673766 cites W2153771870 @default.
- W4281673766 cites W2156123588 @default.