Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281676976> ?p ?o ?g. }
- W4281676976 abstract "Ribonuclease S (RNase S) is an enzyme that exhibits anticancer activity by degrading RNAs within cancer cells; however, the cellular uptake efficiency is low due to its small molecular size. Here we generated RNase S-decorated artificial viral capsids with a size of 70-170 nm by self-assembly of the β-annulus-S-peptide followed by reconstitution with S-protein at neutral pH. The RNase S-decorated artificial viral capsids are efficiently taken up by HepG2 cells and exhibit higher RNA degradation activity in cells compared with RNase S alone. Cell viability assays revealed that RNase S-decorated capsids have high anticancer activity comparable to that of standard anticancer drugs." @default.
- W4281676976 created "2022-06-13" @default.
- W4281676976 creator A5021655332 @default.
- W4281676976 creator A5022968244 @default.
- W4281676976 creator A5029885608 @default.
- W4281676976 creator A5061390597 @default.
- W4281676976 creator A5091604953 @default.
- W4281676976 date "2022-06-21" @default.
- W4281676976 modified "2023-10-01" @default.
- W4281676976 title "Anticancer Activity of Reconstituted Ribonuclease S‐Decorated Artificial Viral Capsid" @default.
- W4281676976 cites W1482111439 @default.
- W4281676976 cites W1536908266 @default.
- W4281676976 cites W1891386810 @default.
- W4281676976 cites W1964868410 @default.
- W4281676976 cites W1967369860 @default.
- W4281676976 cites W1979001545 @default.
- W4281676976 cites W1987293699 @default.
- W4281676976 cites W1991479787 @default.
- W4281676976 cites W1994843166 @default.
- W4281676976 cites W2014817855 @default.
- W4281676976 cites W2018447261 @default.
- W4281676976 cites W2021331078 @default.
- W4281676976 cites W2038332628 @default.
- W4281676976 cites W2038573488 @default.
- W4281676976 cites W2043199702 @default.
- W4281676976 cites W2044330296 @default.
- W4281676976 cites W2044592471 @default.
- W4281676976 cites W2047221872 @default.
- W4281676976 cites W2049595125 @default.
- W4281676976 cites W2051546721 @default.
- W4281676976 cites W2053643552 @default.
- W4281676976 cites W2062207310 @default.
- W4281676976 cites W2072639163 @default.
- W4281676976 cites W2076024443 @default.
- W4281676976 cites W2079699168 @default.
- W4281676976 cites W2080199877 @default.
- W4281676976 cites W2108627855 @default.
- W4281676976 cites W2114918609 @default.
- W4281676976 cites W2125249824 @default.
- W4281676976 cites W2127473737 @default.
- W4281676976 cites W2129367712 @default.
- W4281676976 cites W2133148622 @default.
- W4281676976 cites W2151364212 @default.
- W4281676976 cites W2152772492 @default.
- W4281676976 cites W2161319482 @default.
- W4281676976 cites W2171083652 @default.
- W4281676976 cites W2329476392 @default.
- W4281676976 cites W2415183483 @default.
- W4281676976 cites W2433987067 @default.
- W4281676976 cites W2462037018 @default.
- W4281676976 cites W2491008760 @default.
- W4281676976 cites W2605029885 @default.
- W4281676976 cites W2619215515 @default.
- W4281676976 cites W2626437635 @default.
- W4281676976 cites W2643596984 @default.
- W4281676976 cites W2744534591 @default.
- W4281676976 cites W2751561446 @default.
- W4281676976 cites W2779879953 @default.
- W4281676976 cites W2805632495 @default.
- W4281676976 cites W2810916393 @default.
- W4281676976 cites W2887157195 @default.
- W4281676976 cites W2901767113 @default.
- W4281676976 cites W2922989875 @default.
- W4281676976 cites W2942563652 @default.
- W4281676976 cites W2944456503 @default.
- W4281676976 cites W2948273593 @default.
- W4281676976 cites W2951740695 @default.
- W4281676976 cites W2951794355 @default.
- W4281676976 cites W2958679580 @default.
- W4281676976 cites W2981875117 @default.
- W4281676976 cites W2987216513 @default.
- W4281676976 cites W2993083022 @default.
- W4281676976 cites W2996765131 @default.
- W4281676976 cites W3028348779 @default.
- W4281676976 cites W3100255025 @default.
- W4281676976 cites W3100680092 @default.
- W4281676976 cites W3120666775 @default.
- W4281676976 cites W4206540355 @default.
- W4281676976 cites W4211216439 @default.
- W4281676976 cites W4242490633 @default.
- W4281676976 cites W4244926023 @default.
- W4281676976 cites W4281676976 @default.
- W4281676976 doi "https://doi.org/10.1002/cbic.202200220" @default.
- W4281676976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35676201" @default.
- W4281676976 hasPublicationYear "2022" @default.
- W4281676976 type Work @default.
- W4281676976 citedByCount "5" @default.
- W4281676976 countsByYear W42816769762022 @default.
- W4281676976 countsByYear W42816769762023 @default.
- W4281676976 crossrefType "journal-article" @default.
- W4281676976 hasAuthorship W4281676976A5021655332 @default.
- W4281676976 hasAuthorship W4281676976A5022968244 @default.
- W4281676976 hasAuthorship W4281676976A5029885608 @default.
- W4281676976 hasAuthorship W4281676976A5061390597 @default.
- W4281676976 hasAuthorship W4281676976A5091604953 @default.
- W4281676976 hasBestOaLocation W42816769761 @default.
- W4281676976 hasConcept C104317684 @default.
- W4281676976 hasConcept C10879258 @default.
- W4281676976 hasConcept C12554922 @default.
- W4281676976 hasConcept C153911025 @default.