Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281680745> ?p ?o ?g. }
- W4281680745 endingPage "100877" @default.
- W4281680745 startingPage "100877" @default.
- W4281680745 abstract "The purpose of this review is to describe the existing literature regarding the relationship between the vaginal microbiome, human papillomavirus persistence, and cervical cancer risk, as well as to discuss factors that mediate these relationships. Data suggest that alterations in the vaginal microbiome affect the risk of human papillomavirus infection and persistence, which has downstream effects on cervical dysplasia and cancer risk. The homeostatic Lactobillus species L. crispatus, L. gasseri, L. jensenii act to promote a healthy vaginal environment, while L. iners and pathogens causing bacterial vaginosis are associated with increased inflammation, human papillomavirus infection, cervical dysplasia, and potentially cancer. There are, however, still several large gaps in the literature, particularly related to the modifiable and non-modifiable factors that affect the vaginal microbiome and ensuing risk of pre-cancerous and cancerous lesions. Evidence currently suggests that endogenous and exogenous hormones, tobacco products, and sexual practices influence vaginal microbiome composition, but the nuances of these relationships and how changes in these factors affect dysplasia risk are yet to be delineated. Other studies examining how diet, exercise, race, socioeconomic status, and genetic factors influence the vaginal microbiome are difficult to interpret in the setting of multiple confounders. Future studies should focus on how changes in these modulatory factors might promote a healthy vaginal microbiome to prevent or treat dysplasia in the lower female genital tract." @default.
- W4281680745 created "2022-06-13" @default.
- W4281680745 creator A5002522260 @default.
- W4281680745 creator A5015732636 @default.
- W4281680745 creator A5023103534 @default.
- W4281680745 creator A5043044043 @default.
- W4281680745 date "2022-08-01" @default.
- W4281680745 modified "2023-09-30" @default.
- W4281680745 title "The vaginal microbiome: A complex milieu affecting risk of human papillomavirus persistence and cervical cancer" @default.
- W4281680745 cites W1519033599 @default.
- W4281680745 cites W1769099349 @default.
- W4281680745 cites W1910585352 @default.
- W4281680745 cites W1919603305 @default.
- W4281680745 cites W1952594819 @default.
- W4281680745 cites W1963567457 @default.
- W4281680745 cites W1969732431 @default.
- W4281680745 cites W1969795550 @default.
- W4281680745 cites W1972528270 @default.
- W4281680745 cites W1972996919 @default.
- W4281680745 cites W1977179183 @default.
- W4281680745 cites W1981221946 @default.
- W4281680745 cites W1986223387 @default.
- W4281680745 cites W1989231157 @default.
- W4281680745 cites W1991191092 @default.
- W4281680745 cites W1992519297 @default.
- W4281680745 cites W2002903900 @default.
- W4281680745 cites W2004522065 @default.
- W4281680745 cites W2006826127 @default.
- W4281680745 cites W2007401297 @default.
- W4281680745 cites W2008732636 @default.
- W4281680745 cites W2013371150 @default.
- W4281680745 cites W2014139466 @default.
- W4281680745 cites W2017153096 @default.
- W4281680745 cites W2023506796 @default.
- W4281680745 cites W2024580195 @default.
- W4281680745 cites W2027297424 @default.
- W4281680745 cites W2028835702 @default.
- W4281680745 cites W2029010517 @default.
- W4281680745 cites W2034235918 @default.
- W4281680745 cites W2036351016 @default.
- W4281680745 cites W2037270914 @default.
- W4281680745 cites W2037455811 @default.
- W4281680745 cites W2038125204 @default.
- W4281680745 cites W2039194112 @default.
- W4281680745 cites W2040891942 @default.
- W4281680745 cites W2041307935 @default.
- W4281680745 cites W2048325355 @default.
- W4281680745 cites W2050317906 @default.
- W4281680745 cites W2050664909 @default.
- W4281680745 cites W2051033048 @default.
- W4281680745 cites W2052303436 @default.
- W4281680745 cites W2052969143 @default.
- W4281680745 cites W2067361562 @default.
- W4281680745 cites W2067973725 @default.
- W4281680745 cites W2070338467 @default.
- W4281680745 cites W2073417582 @default.
- W4281680745 cites W2073545106 @default.
- W4281680745 cites W2077048092 @default.
- W4281680745 cites W2081065988 @default.
- W4281680745 cites W2081831291 @default.
- W4281680745 cites W2084070275 @default.
- W4281680745 cites W2087019729 @default.
- W4281680745 cites W2088090700 @default.
- W4281680745 cites W2090301155 @default.
- W4281680745 cites W2095794160 @default.
- W4281680745 cites W2096360080 @default.
- W4281680745 cites W2097493772 @default.
- W4281680745 cites W2098491904 @default.
- W4281680745 cites W2100466857 @default.
- W4281680745 cites W2102100232 @default.
- W4281680745 cites W2105182622 @default.
- W4281680745 cites W2111415362 @default.
- W4281680745 cites W2112804729 @default.
- W4281680745 cites W2114813165 @default.
- W4281680745 cites W2117845405 @default.
- W4281680745 cites W2117874572 @default.
- W4281680745 cites W2117995803 @default.
- W4281680745 cites W2119731982 @default.
- W4281680745 cites W2120467821 @default.
- W4281680745 cites W2128281435 @default.
- W4281680745 cites W2129650487 @default.
- W4281680745 cites W2130121301 @default.
- W4281680745 cites W2131255017 @default.
- W4281680745 cites W2133206252 @default.
- W4281680745 cites W2134931724 @default.
- W4281680745 cites W2136236728 @default.
- W4281680745 cites W2136303292 @default.
- W4281680745 cites W2140455334 @default.
- W4281680745 cites W2142116340 @default.
- W4281680745 cites W2145224687 @default.
- W4281680745 cites W2145530051 @default.
- W4281680745 cites W2147540401 @default.
- W4281680745 cites W2149302632 @default.
- W4281680745 cites W2149967357 @default.
- W4281680745 cites W2152821355 @default.
- W4281680745 cites W2156591001 @default.
- W4281680745 cites W2158902491 @default.
- W4281680745 cites W2162088345 @default.