FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281681504> ?p ?o ?g. }

• W4281681504 abstract "Background: Pre-eclampsia is a serious consideration for women with type 1 diabetes mellitus (T1DM) planning pregnancy. Risk stratification strategies, such as biomarkers measured in the first trimester of pregnancy, could help identify high-risk women. The literature on T1DM-specific pre-eclampsia biomarkers is expanding. We aimed to provide a narrative review of recently published evidence to identify the most promising biomarker candidates that could be targeted for clinical implementation in existing PE models. Methods: A search using MeSH terms was carried out of Medline, EMBASE, Maternity and Infant Care, Web of Science, and Scopus for relevant papers published since 2015 inclusive and in English. The time limit was applied from the publication of the preceding systematic review in this field. Included studies had pre-eclampsia as a primary outcome, measured one or more serum, plasma or urine biomarkers at any time during pregnancy, and had a distinct group of women with T1DM who developed pre-eclampsia. Studies with pre-eclampsia as a composite outcome were not considered. No restrictions on study types were applied. A narrative synthesis approach was adopted for analysis. Results: A total of 510 records were screened yielding 18 eligible studies relating to 32 different biomarkers. Higher first-trimester levels of HbA1c and urinary albumin were associated with an increased risk of pre-eclampsia development in women with T1DM. Urinary neutrophil gelatinase-associated lipocalin and adipokines were novel biomarkers showing moderate predictive ability before 15 gestational weeks. Two T1DM-specific pre-eclampsia prediction models were proposed, measuring adipokines or urinary neutrophil gelatinase-associated lipocalin together with easily attainable maternal clinical characteristics. Contradicting previous literature, pre-eclampsia risk in women with T1DM was correlated with vitamin D levels and atherogenic lipid profile in the context of haptoglobin phenotype 2-2. Pregnancy-associated plasma protein-A and soluble endoglin did not predict pre-eclampsia in women with T1DM, and soluble Fms-like tyrosine kinase 1 only predicted pre-eclampsia from the third trimester. Conclusion: Maternally derived biomarkers reflecting glycemic control, insulin resistance and renal dysfunction performed better as PE predictors among women with T1DM than those derived from the placenta. These biomarkers could be trialed in current PE prediction algorithms to tailor them for women with T1DM." @default.
• W4281681504 created "2022-06-13" @default.
• W4281681504 creator A5002507101 @default.
• W4281681504 creator A5040078827 @default.
• W4281681504 creator A5052868080 @default.
• W4281681504 creator A5090157445 @default.
• W4281681504 date "2022-05-26" @default.
• W4281681504 modified "2023-10-14" @default.
• W4281681504 title "Pre-Eclampsia Biomarkers for Women With Type 1 Diabetes Mellitus: A Comprehensive Review of Recent Literature" @default.
• W4281681504 cites W1492212171 @default.
• W4281681504 cites W1580167980 @default.
• W4281681504 cites W1602374922 @default.
• W4281681504 cites W1926159205 @default.
• W4281681504 cites W1963894856 @default.
• W4281681504 cites W1970616831 @default.
• W4281681504 cites W1984013931 @default.
• W4281681504 cites W1984076846 @default.
• W4281681504 cites W1986022761 @default.
• W4281681504 cites W1992568131 @default.
• W4281681504 cites W2023396695 @default.
• W4281681504 cites W2031471245 @default.
• W4281681504 cites W2036954961 @default.
• W4281681504 cites W2037642647 @default.
• W4281681504 cites W2039573830 @default.
• W4281681504 cites W2044074790 @default.
• W4281681504 cites W2044437167 @default.
• W4281681504 cites W2045838083 @default.
• W4281681504 cites W2051354670 @default.
• W4281681504 cites W2060481095 @default.
• W4281681504 cites W2072466774 @default.
• W4281681504 cites W2118358710 @default.
• W4281681504 cites W2122059901 @default.
• W4281681504 cites W2133189589 @default.
• W4281681504 cites W2150157189 @default.
• W4281681504 cites W2163935256 @default.
• W4281681504 cites W2169826348 @default.
• W4281681504 cites W2186073284 @default.
• W4281681504 cites W2187025414 @default.
• W4281681504 cites W2262812493 @default.
• W4281681504 cites W2271332509 @default.
• W4281681504 cites W2283512836 @default.
• W4281681504 cites W2332128238 @default.
• W4281681504 cites W2410125730 @default.
• W4281681504 cites W2513494484 @default.
• W4281681504 cites W2519045228 @default.
• W4281681504 cites W2550032207 @default.
• W4281681504 cites W2621290943 @default.
• W4281681504 cites W2624543460 @default.
• W4281681504 cites W2730504020 @default.
• W4281681504 cites W2750839862 @default.
• W4281681504 cites W2752892555 @default.
• W4281681504 cites W2763419546 @default.
• W4281681504 cites W2767403471 @default.
• W4281681504 cites W2773708894 @default.
• W4281681504 cites W2774435616 @default.
• W4281681504 cites W2795370579 @default.
• W4281681504 cites W2897808103 @default.
• W4281681504 cites W2915039200 @default.
• W4281681504 cites W2943955530 @default.
• W4281681504 cites W2949184859 @default.
• W4281681504 cites W2980131600 @default.
• W4281681504 cites W2981069599 @default.
• W4281681504 cites W3003132229 @default.
• W4281681504 cites W3013853501 @default.
• W4281681504 cites W3015922023 @default.
• W4281681504 cites W3039401173 @default.
• W4281681504 cites W3041992880 @default.
• W4281681504 cites W3042661563 @default.
• W4281681504 cites W3208479355 @default.
• W4281681504 cites W4211123156 @default.
• W4281681504 cites W4251118184 @default.
• W4281681504 cites W4382916220 @default.
• W4281681504 doi "https://doi.org/10.3389/fbioe.2022.809528" @default.
• W4281681504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35721866" @default.
• W4281681504 hasPublicationYear "2022" @default.
• W4281681504 type Work @default.
• W4281681504 citedByCount "1" @default.
• W4281681504 countsByYear W42816815042022 @default.
• W4281681504 crossrefType "journal-article" @default.
• W4281681504 hasAuthorship W4281681504A5002507101 @default.
• W4281681504 hasAuthorship W4281681504A5040078827 @default.
• W4281681504 hasAuthorship W4281681504A5052868080 @default.
• W4281681504 hasAuthorship W4281681504A5090157445 @default.
• W4281681504 hasBestOaLocation W42816815041 @default.
• W4281681504 hasConcept C126322002 @default.
• W4281681504 hasConcept C131872663 @default.
• W4281681504 hasConcept C134018914 @default.
• W4281681504 hasConcept C2779234561 @default.
• W4281681504 hasConcept C2779434492 @default.
• W4281681504 hasConcept C2781197716 @default.
• W4281681504 hasConcept C2781232474 @default.
• W4281681504 hasConcept C2781276381 @default.
• W4281681504 hasConcept C46973012 @default.
• W4281681504 hasConcept C54355233 @default.
• W4281681504 hasConcept C55493867 @default.
• W4281681504 hasConcept C555293320 @default.
• W4281681504 hasConcept C71924100 @default.
• W4281681504 hasConcept C77411442 @default.
• W4281681504 hasConcept C86803240 @default.
• W4281681504 hasConceptScore W4281681504C126322002 @default.

• next