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• W4281707034 abstract "Objective This study aimed to evaluate the effects of resistance training (RT) combined with prebiotic β-glucan (BG) ingestion (Saccharomyces cerevisiae) in ovariectomized (OVX) mice.Methods Forty-eight mice were divided into six treatments: SHAM group and five OVX groups treated with saline (SAL), alendronate (ALE) (0.1 mg/kg), BG (62.5 mg/kg), RT (climbing a ladder with load) and the combination of BG + RT. All treatments were performed three times per week for 8 weeks starting 38 days after ovariectomy.Results OVX effectiveness was confirmed by a reduction in uterus mass (p < 0.05). Femur weight was higher in the SHAM group, followed by the ALE and RT groups with intermediate values and the BG + RT, BG and SAL groups with the lowest values (p < 0.05). The bone mineral density (BMDDEXA) results were higher for the SHAM and RT groups compared to the other groups (p < 0.05). RT provided similar bone mass and resistance to fracture to ALE and SHAM. We found a similar number of osteocytes in the RT and SHAM groups, which was significantly higher than that found in animals receiving BG (p < 0.05). The BG + RT combination increased calcium bone concentration.Conclusion RT promoted benefits on bone health in the OVX model, which were not complemented by the consumption of BG." @default.
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• W4281707034 date "2022-06-02" @default.
• W4281707034 modified "2023-10-16" @default.
• W4281707034 title "Effect of resistance training combined with β-glucan ingestion on bone of ovariectomized mice" @default.
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• W4281707034 doi "https://doi.org/10.1080/13697137.2022.2077097" @default.
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