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• W4281709175 endingPage "98" @default.
• W4281709175 startingPage "89" @default.
• W4281709175 abstract "Diabetes mellitus (DM) is associated with musculoskeletal complications-including tendon dysfunction and injury. Patients with DM show altered foot and ankle mechanics that have been attributed to tendon dysfunction as well as impaired recovery post-tendon injury. Despite the problem of DM-related tendon complications, treatment guidelines specific to this population of individuals are lacking. DM impairs tendon structure, function, and healing capacity in tendons throughout the body, but the Achilles tendon is of particular concern and most studied in the diabetic foot. At macroscopic levels, asymptomatic, diabetic Achilles tendons may show morphological abnormalities such as thickening, collagen disorganization, and/or calcific changes at the tendon enthesis. At smaller length scales, DM affects collagen sliding and discrete plasticity due to glycation of collagen. However, how these alterations translate to mechanical deficits observed at larger length scales is an area of continued investigation. In addition to dysfunction of the extracellular matrix, tendon cells such as tenocytes and tendon stem/progenitor cells show significant abnormalities in proliferation, apoptosis, and remodeling capacity in the presence of hyperglycemia and advanced glycation end-products, thus contributing to the disruption of tendon homeostasis and healing. Improving our understanding of the effects of DM on tendons-from molecular pathways to patients-will progress toward targeted therapies in this group at high risk of foot and ankle morbidity." @default.
• W4281709175 created "2022-06-13" @default.
• W4281709175 creator A5000531118 @default.
• W4281709175 creator A5017401858 @default.
• W4281709175 creator A5032196334 @default.
• W4281709175 date "2022-06-02" @default.
• W4281709175 modified "2023-10-16" @default.
• W4281709175 title "Effect of Diabetes on Tendon Structure and Function: Not Limited to Collagen Crosslinking" @default.
• W4281709175 cites W1481180598 @default.
• W4281709175 cites W1512474466 @default.
• W4281709175 cites W1517715606 @default.
• W4281709175 cites W1665067149 @default.
• W4281709175 cites W1876475213 @default.
• W4281709175 cites W1921978279 @default.
• W4281709175 cites W1963699711 @default.
• W4281709175 cites W1966234811 @default.
• W4281709175 cites W1969774185 @default.
• W4281709175 cites W1977802341 @default.
• W4281709175 cites W1980559273 @default.
• W4281709175 cites W1994955098 @default.
• W4281709175 cites W1996014502 @default.
• W4281709175 cites W2013079326 @default.
• W4281709175 cites W2018135697 @default.
• W4281709175 cites W2018620079 @default.
• W4281709175 cites W2024305546 @default.
• W4281709175 cites W2027348958 @default.
• W4281709175 cites W2028703531 @default.
• W4281709175 cites W2034138847 @default.
• W4281709175 cites W2034374758 @default.
• W4281709175 cites W2036743645 @default.
• W4281709175 cites W2042787906 @default.
• W4281709175 cites W2043397658 @default.
• W4281709175 cites W2044437167 @default.
• W4281709175 cites W2045351385 @default.
• W4281709175 cites W2058076354 @default.
• W4281709175 cites W2059934579 @default.
• W4281709175 cites W2064843795 @default.
• W4281709175 cites W2067377927 @default.
• W4281709175 cites W2069718021 @default.
• W4281709175 cites W2074794423 @default.
• W4281709175 cites W2079883205 @default.
• W4281709175 cites W2080439666 @default.
• W4281709175 cites W2082590725 @default.
• W4281709175 cites W2084306805 @default.
• W4281709175 cites W2084536221 @default.
• W4281709175 cites W2085683596 @default.
• W4281709175 cites W2085987545 @default.
• W4281709175 cites W2086327676 @default.
• W4281709175 cites W2087169849 @default.
• W4281709175 cites W2089443962 @default.
• W4281709175 cites W2093227477 @default.
• W4281709175 cites W2095950008 @default.
• W4281709175 cites W2098764018 @default.
• W4281709175 cites W2100322364 @default.
• W4281709175 cites W2106216311 @default.
• W4281709175 cites W2113278103 @default.
• W4281709175 cites W2123560318 @default.
• W4281709175 cites W2123576169 @default.
• W4281709175 cites W2126328491 @default.
• W4281709175 cites W2127661946 @default.
• W4281709175 cites W2128978108 @default.
• W4281709175 cites W2131009584 @default.
• W4281709175 cites W2131990101 @default.
• W4281709175 cites W2133576538 @default.
• W4281709175 cites W2133979481 @default.
• W4281709175 cites W2141399449 @default.
• W4281709175 cites W2150596432 @default.
• W4281709175 cites W2153249592 @default.
• W4281709175 cites W2158837806 @default.
• W4281709175 cites W2162497204 @default.
• W4281709175 cites W2173199507 @default.
• W4281709175 cites W2199076548 @default.
• W4281709175 cites W2319489233 @default.
• W4281709175 cites W2336222708 @default.
• W4281709175 cites W2342205525 @default.
• W4281709175 cites W2403259545 @default.
• W4281709175 cites W2485838710 @default.
• W4281709175 cites W2518854129 @default.
• W4281709175 cites W2530969110 @default.
• W4281709175 cites W2589762027 @default.
• W4281709175 cites W2591988798 @default.
• W4281709175 cites W2615689853 @default.
• W4281709175 cites W2626556529 @default.
• W4281709175 cites W2680717638 @default.
• W4281709175 cites W2767236797 @default.
• W4281709175 cites W2767429408 @default.
• W4281709175 cites W2777182833 @default.
• W4281709175 cites W2778958187 @default.
• W4281709175 cites W2800720885 @default.
• W4281709175 cites W2802765480 @default.
• W4281709175 cites W2805193110 @default.
• W4281709175 cites W2806103936 @default.
• W4281709175 cites W2808080300 @default.
• W4281709175 cites W2808141153 @default.
• W4281709175 cites W2907956254 @default.
• W4281709175 cites W2909287514 @default.
• W4281709175 cites W2921919452 @default.
• W4281709175 cites W2970375682 @default.

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