FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4281735541> ?p ?o ?g. }

• W4281735541 endingPage "164" @default.
• W4281735541 startingPage "155" @default.
• W4281735541 abstract "Anti-cytokine treatments are used in the treatment of severe COVID-19. Other studies have shown statistical significance with TNF inhibitors but not with other biological/targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARD).Compare the rate of severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) infection and the course and incidence of COVID-19 infection in patients who received b/tsDMARD with control patients.Analytical cross-sectional SETTINGS: Tertiary care hospital PATIENTS AND METHODS: All patients who applied to the rheumatology outpatient clinic between June 2020-March 2021 and received b/tsDMARD were included in the study. All patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis who applied to the rheumatology outpatient clinic in the three months before March 2021 and did not receive b/tsDMARD were included as the control group. History of COVID-19 infection and treatments were recorded. Multivariate analysis was performed to assess factors associated with use of tumor necrosis factor (TNF) inhibitors and differences between specific biologic drugs.Rate of COVID-19 disease among patients using biological/targeted synthetic therapy and non-biological/targeted synthetic therapy. COVID-19 clinical outcomes (hospitalization, intensive care admission, mechanical ventilation and death).533 in total; 341 received b/tsDMARD, 212 in the control group that did not receive b/tsDMARD.One hundred patients (18%) had been infected with SARS-COV-2. The difference in SARS-COV-2 infection between b/tsDMARD and the control was statistically significant (13, 2% vs. 25, 9%, respectively) (P<.001). The hospital stays were longer in the controls (P<.001). Multinomial regression analysis revealed that COVID-19 negative patients were more likely to use tumor necrosis factor (TNF) inhibitors (OR: 2, 911; 95% CI: 1.727-4.908; P<.001) compared to COVID-19 positive participants. Multinomial logistic regression analysis indicated that hospitalized patients were more likely to use TNF inhibitors (OR: 11, 006; 95% CI: 3.447-35.138; P<.001) and there was no significant difference between b/tsDMARDs other than TNF inhibitors in frequency of hospitalization.Patients who were medicated with b/tsDMARD were less likely to be infected with COVID-19 and be hospitalized due to the infection. We have found that this effect was particularly dependent on the use of TNF inhibitors.Conducted in a single center and unable to provide a homogeneous study population.None." @default.
• W4281735541 created "2022-06-13" @default.
• W4281735541 creator A5048659524 @default.
• W4281735541 creator A5051647016 @default.
• W4281735541 date "2022-05-01" @default.
• W4281735541 modified "2023-09-25" @default.
• W4281735541 title "Clinical outcomes of patients with COVID-19 and inflammatory rheumatic diseases receiving biological/targeted therapy" @default.
• W4281735541 cites W2166650533 @default.
• W4281735541 cites W2786782352 @default.
• W4281735541 cites W2935343188 @default.
• W4281735541 cites W3001118548 @default.
• W4281735541 cites W3014050022 @default.
• W4281735541 cites W3015353977 @default.
• W4281735541 cites W3015861468 @default.
• W4281735541 cites W3016936957 @default.
• W4281735541 cites W3021024241 @default.
• W4281735541 cites W3021391038 @default.
• W4281735541 cites W3024016727 @default.
• W4281735541 cites W3024177957 @default.
• W4281735541 cites W3027256113 @default.
• W4281735541 cites W3030371932 @default.
• W4281735541 cites W3035622686 @default.
• W4281735541 cites W3045623013 @default.
• W4281735541 cites W3046565293 @default.
• W4281735541 cites W3047617837 @default.
• W4281735541 cites W3081452237 @default.
• W4281735541 cites W3084628013 @default.
• W4281735541 cites W3093149116 @default.
• W4281735541 cites W3108737232 @default.
• W4281735541 cites W3116391793 @default.
• W4281735541 cites W3124292577 @default.
• W4281735541 cites W3124810175 @default.
• W4281735541 cites W3126416594 @default.
• W4281735541 cites W3129735571 @default.
• W4281735541 cites W3129842474 @default.
• W4281735541 cites W3129869280 @default.
• W4281735541 cites W3134935611 @default.
• W4281735541 cites W3139115512 @default.
• W4281735541 cites W3164519882 @default.
• W4281735541 doi "https://doi.org/10.5144/0256-4947.2022.155" @default.
• W4281735541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35658585" @default.
• W4281735541 hasPublicationYear "2022" @default.
• W4281735541 type Work @default.
• W4281735541 citedByCount "0" @default.
• W4281735541 crossrefType "journal-article" @default.
• W4281735541 hasAuthorship W4281735541A5048659524 @default.
• W4281735541 hasAuthorship W4281735541A5051647016 @default.
• W4281735541 hasBestOaLocation W42817355411 @default.
• W4281735541 hasConcept C120665830 @default.
• W4281735541 hasConcept C121332964 @default.
• W4281735541 hasConcept C126322002 @default.
• W4281735541 hasConcept C198451711 @default.
• W4281735541 hasConcept C2776260265 @default.
• W4281735541 hasConcept C2777138892 @default.
• W4281735541 hasConcept C2777178219 @default.
• W4281735541 hasConcept C2777575956 @default.
• W4281735541 hasConcept C2779134260 @default.
• W4281735541 hasConcept C3020110884 @default.
• W4281735541 hasConcept C61511704 @default.
• W4281735541 hasConcept C71924100 @default.
• W4281735541 hasConceptScore W4281735541C120665830 @default.
• W4281735541 hasConceptScore W4281735541C121332964 @default.
• W4281735541 hasConceptScore W4281735541C126322002 @default.
• W4281735541 hasConceptScore W4281735541C198451711 @default.
• W4281735541 hasConceptScore W4281735541C2776260265 @default.
• W4281735541 hasConceptScore W4281735541C2777138892 @default.
• W4281735541 hasConceptScore W4281735541C2777178219 @default.
• W4281735541 hasConceptScore W4281735541C2777575956 @default.
• W4281735541 hasConceptScore W4281735541C2779134260 @default.
• W4281735541 hasConceptScore W4281735541C3020110884 @default.
• W4281735541 hasConceptScore W4281735541C61511704 @default.
• W4281735541 hasConceptScore W4281735541C71924100 @default.
• W4281735541 hasIssue "3" @default.
• W4281735541 hasLocation W42817355411 @default.
• W4281735541 hasLocation W42817355412 @default.
• W4281735541 hasLocation W42817355413 @default.
• W4281735541 hasLocation W42817355414 @default.
• W4281735541 hasOpenAccess W4281735541 @default.
• W4281735541 hasPrimaryLocation W42817355411 @default.
• W4281735541 hasRelatedWork W1539773147 @default.
• W4281735541 hasRelatedWork W2014287001 @default.
• W4281735541 hasRelatedWork W2025143817 @default.
• W4281735541 hasRelatedWork W2046399730 @default.
• W4281735541 hasRelatedWork W2058910435 @default.
• W4281735541 hasRelatedWork W2091388803 @default.
• W4281735541 hasRelatedWork W2736593664 @default.
• W4281735541 hasRelatedWork W2765385402 @default.
• W4281735541 hasRelatedWork W4252499066 @default.
• W4281735541 hasRelatedWork W4253845763 @default.
• W4281735541 hasVolume "42" @default.
• W4281735541 isParatext "false" @default.
• W4281735541 isRetracted "false" @default.
• W4281735541 workType "article" @default.